Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Jothilingam Sivapackiam"'
Autor:
Yeawon Kim, Chuang Li, Chenjian Gu, Yili Fang, Eric Tycksen, Anuradhika Puri, Terri A. Pietka, Jothilingam Sivapackiam, Kendrah Kidd, Sun-Ji Park, Bryce G. Johnson, Stanislav Kmoch, Jeremy S. Duffield, Anthony J. Bleyer, Meredith E. Jackrel, Fumihiko Urano, Vijay Sharma, Maria Lindahl, Ying Maggie Chen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
Abstract Misfolded protein aggregates may cause toxic proteinopathy, including autosomal dominant tubulointerstitial kidney disease due to uromodulin mutations (ADTKD-UMOD), a leading hereditary kidney disease. There are no targeted therapies. In our
Externí odkaz:
https://doaj.org/article/72c2d4d2fcd54509bc61bc5046fee857
Autor:
Jothilingam Sivapackiam, Fuyi Liao, Dequan Zhou, Kooresh I. Shoghi, Robert J. Gropler, Andrew E. Gelman, Vijay Sharma
Publikováno v:
Redox Biology, Vol 37, Iss , Pp 101690- (2020)
Overproduction of reactive oxygen species (ROS) is a well-established indicator of ongoing tissue inflammation. However, there is a scarcity of molecular imaging probes capable of providing noninvasive sensitive detection of ROS for allowing longitud
Externí odkaz:
https://doaj.org/article/1304ed9823a34fb09c298ec72cf8f7e3
68Ga-Galmydar: A PET imaging tracer for noninvasive detection of Doxorubicin-induced cardiotoxicity.
Autor:
Jothilingam Sivapackiam, Shivesh Kabra, Sylvia Speidel, Monica Sharma, Richard Laforest, Amber Salter, Michael P Rettig, Vijay Sharma
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0215579 (2019)
BackgroundCancer patients undergoing Doxorubicin (DOX) treatment are susceptible to acute and chronic cardiac anomalies, including aberrant arrhythmias, ventricular dysfunction, and heart failure. To stratify patients at high risk for DOX -related he
Externí odkaz:
https://doaj.org/article/f1b897dd2ea64f42a735776d98b9b366
Autor:
Vijay Sharma, Jothilingam Sivapackiam, Scott E Harpstrite, Julie L Prior, Hannah Gu, Nigam P Rath, David Piwnica-Worms
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109361 (2014)
Lipophilic cationic technetium-99m-complexes are widely used for myocardial perfusion imaging (MPI). However, inherent uncertainties in the supply chain of molybdenum-99, the parent isotope required for manufacturing 99Mo/99mTc generators, intensifie
Externí odkaz:
https://doaj.org/article/4f97e51d704e4f9bb1f27eeb9a2b3966
Publikováno v:
International Journal of Cardiology.
Autor:
Katherine N. Weilbaecher, Gregory M. Lanza, Deborah J. Veis, Samuel Achilefu, Vijay Sharma, James A.J. Fitzpatrick, Suzanne J. Bakewell, Christopher A. Maher, Sheila A. Stewart, Jothilingam Sivapackiam, Ha X. Dang, Kristen Pagliai, Elizabeth Cordell, Alison K. Esser, Jingyu Xiang, Francesca Fontana, Michael H. Ross, Kristin A. Kwakwa, Yalin Xu, Jennifer L. Davis, Xinming Su, Gregory C. Fox
Flow cytometric analysis of integrin β3 staining on breast cancer cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43e9581b72d1638425a68a9cf4116a21
https://doi.org/10.1158/1535-7163.22521954
https://doi.org/10.1158/1535-7163.22521954
Autor:
Katherine N. Weilbaecher, Gregory M. Lanza, Deborah J. Veis, Samuel Achilefu, Vijay Sharma, James A.J. Fitzpatrick, Suzanne J. Bakewell, Christopher A. Maher, Sheila A. Stewart, Jothilingam Sivapackiam, Ha X. Dang, Kristen Pagliai, Elizabeth Cordell, Alison K. Esser, Jingyu Xiang, Francesca Fontana, Michael H. Ross, Kristin A. Kwakwa, Yalin Xu, Jennifer L. Davis, Xinming Su, Gregory C. Fox
Breast cancer bone metastases are common and incurable. Tumoral integrin β3 (β3) expression is induced through interaction with the bone microenvironment. Although β3 is known to promote bone colonization, its functional role during therapy of est
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e9742668dcb390c0c8c105e42940932
https://doi.org/10.1158/1535-7163.c.6543234.v1
https://doi.org/10.1158/1535-7163.c.6543234.v1
Autor:
Katherine N. Weilbaecher, Gregory M. Lanza, Deborah J. Veis, Samuel Achilefu, Vijay Sharma, James A.J. Fitzpatrick, Suzanne J. Bakewell, Christopher A. Maher, Sheila A. Stewart, Jothilingam Sivapackiam, Ha X. Dang, Kristen Pagliai, Elizabeth Cordell, Alison K. Esser, Jingyu Xiang, Francesca Fontana, Michael H. Ross, Kristin A. Kwakwa, Yalin Xu, Jennifer L. Davis, Xinming Su, Gregory C. Fox
Additional details for methods and materials.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9309dd7771e5cd446cd418e97885e924
https://doi.org/10.1158/1535-7163.22521936.v1
https://doi.org/10.1158/1535-7163.22521936.v1
Autor:
Sun-Ji Park, Yeawon Kim, Chuang Li, Junwoo Suh, Jothilingam Sivapackiam, Tassia M. Goncalves, George Jarad, Guoyan Zhao, Fumihiko Urano, Vijay Sharma, Ying Maggie Chen
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(35)
Albuminuria is a hallmark of glomerular disease of various etiologies. It is not only a symptom of glomerular disease but also a cause leading to glomerulosclerosis, interstitial fibrosis, and eventually, a decline in kidney function. The molecular m
Autor:
Samuel Achilefu, Michael H. Ross, Jingyu Xiang, Kristin A. Kwakwa, Elizabeth Cordell, Alison K. Esser, Vivek Sharma, Kristen Pagliai, Francesca Fontana, Jennifer L. Davis, Deborah J. Veis, Suzanne J. Bakewell, Xinming Su, Gregory M. Lanza, Katherine N. Weilbaecher, Gregory C. Fox, Christopher G. Maher, Jothilingam Sivapackiam, James A. J. Fitzpatrick, Yalin Xu, Ha X. Dang, Sheila A. Stewart
Publikováno v:
Mol Cancer Ther
Breast cancer bone metastases are common and incurable. Tumoral integrin β3 (β3) expression is induced through interaction with the bone microenvironment. Although β3 is known to promote bone colonization, its functional role during therapy of est