Chemical Proteomics Identifies SLC25A20 as a Functional Target of the Ingenol Class of Actinic Keratosis Drugs.

Autor: Parker CG; Department of Molecular Medicine, The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California 92037, United States., Kuttruff CA; Department of Chemistry, The Scripps Research Institute, La Jolla, California 92037, United States., Galmozzi A; Department of Molecular Medicine, The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California 92037, United States., Jørgensen L; Research & Development, LEO Pharma, DK-2750 Ballerup, Denmark., Yeh CH; Department of Chemistry, The Scripps Research Institute, La Jolla, California 92037, United States., Hermanson DJ; Department of Molecular Medicine, The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California 92037, United States., Wang Y; Department of Molecular Medicine, The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California 92037, United States., Artola M; Department of Chemistry, The Scripps Research Institute, La Jolla, California 92037, United States., McKerrall SJ; Department of Chemistry, The Scripps Research Institute, La Jolla, California 92037, United States., Josyln CM; Department of Molecular Medicine, The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California 92037, United States., Nørremark B; Research & Development, LEO Pharma, DK-2750 Ballerup, Denmark., Dünstl G; Research & Development, LEO Pharma, DK-2750 Ballerup, Denmark., Felding J; Research & Development, LEO Pharma, DK-2750 Ballerup, Denmark., Saez E; Department of Molecular Medicine, The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California 92037, United States., Baran PS; Department of Chemistry, The Scripps Research Institute, La Jolla, California 92037, United States., Cravatt BF; Department of Molecular Medicine, The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California 92037, United States.

Publikováno v: ACS central science [ACS Cent Sci] 2017 Dec 27; Vol. 3 (12), pp. 1276-1285. Date of Electronic Publication: 2017 Dec 06.