Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Josué da Costa Lima-Junior"'
Autor:
Ada da Silva Matos, Isabela Ferreira Soares, Rodrigo Nunes Rodrigues-da-Silva, Cinthia Magalhães Rodolphi, Letusa Albrecht, Rafael Amaral Donassolo, Cesar Lopez-Camacho, Ana Paula Dinis Ano Bom, Patrícia Cristina da Costa Neves, Fernando de Paiva Conte, Lilian Rose Pratt-Riccio, Cláudio Tadeu Daniel-Ribeiro, Paulo Renato Rivas Totino, Josué da Costa Lima-Junior
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
In the Americas, P. vivax is the predominant causative species of malaria, a debilitating and economically significant disease. Due to the complexity of the malaria parasite life cycle, a vaccine formulation with multiple antigens expressed in variou
Externí odkaz:
https://doaj.org/article/beb207a3a85f4e0ea688e8e6c4a1ea29
Autor:
Cinthia Magalhães Rodolphi, Isabela Ferreira Soares, Ada da Silva Matos, Rodrigo Nunes Rodrigues-da-Silva, Marcelo Urbano Ferreira, Lilian Rose Pratt-Riccio, Paulo Renato Rivas Totino, Kézia Katiani Gorza Scopel, Josué da Costa Lima-Junior
Publikováno v:
Antibodies, Vol 13, Iss 3, p 69 (2024)
Malaria is a serious health problem worldwide affecting mainly children and socially vulnerable people. The biological particularities of P. vivax, such as the ability to generate dormant liver stages, the rapid maturation of gametocytes, and the eme
Externí odkaz:
https://doaj.org/article/089ca110c9dd4df093e7ea19ecdc4da0
Publikováno v:
Vaccines, Vol 11, Iss 11, p 1632 (2023)
In the 18th century, English physician Edward Jenner laid the foundation for modern vaccination by achieving protection against variola [...]
Externí odkaz:
https://doaj.org/article/007a43ec25dc4fd69ecdf5f956454ba1
Autor:
Ada da Silva Matos, Isabela Ferreira Soares, Barbara de Oliveira Baptista, Hugo Amorim dos Santos de Souza, Lana Bitencourt Chaves, Daiana de Souza Perce-da-Silva, Evelyn Kety Pratt Riccio, Letusa Albrecht, Paulo Renato Rivas Totino, Rodrigo Nunes Rodrigues-da-Silva, Cláudio Tadeu Daniel-Ribeiro, Lilian Rose Pratt-Riccio, Josué da Costa Lima-Junior
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 14, p 11571 (2023)
The PvCelTOS, PvCyRPA, and Pvs25 proteins play important roles during the three stages of the P. vivax lifecycle. In this study, we designed and expressed a P. vivax recombinant modular chimeric protein (PvRMC-1) composed of the main antigenic region
Externí odkaz:
https://doaj.org/article/3064eb2def1c48c986a32cfa46d0151b
Autor:
Edlainne Pinheiro Ferreira-Sena, Daiana de Jesus Hardoim, Flavia de Oliveira Cardoso, Luiz Ney d’Escoffier, Isabela Ferreira Soares, João Pedro Rangel da Silva Carvalho, Ricardo Almir Angnes, Stenio Perdigão Fragoso, Carlos Roberto Alves, Salvatore Giovanni De-Simone, Josué da Costa Lima-Junior, Alvaro Luiz Bertho, Tânia Zaverucha-do-Valle, Franklin Souza da Silva, Kátia da Silva Calabrese
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5972 (2023)
Leishmaniasis represents a complex of diseases with a broad clinical spectrum and epidemiological diversity, considered a major public health problem. Although there is treatment, there are still no vaccines for cutaneous leishmaniasis. Because Leish
Externí odkaz:
https://doaj.org/article/257484197f2144789477e83632e2e248
Autor:
Laura Sant’Anna Ataides, Fernanda de Moraes Maia, Fernando Paiva Conte, Lourdes Isaac, Angela Silva Barbosa, Josué da Costa Lima-Junior, Kátia Eliane Santos Avelar, Rodrigo Nunes Rodrigues-da-Silva
Publikováno v:
Vaccines, Vol 11, Iss 2, p 359 (2023)
Sphingomyelin is a major constituent of eukaryotic cell membranes, and if degraded by bacteria sphingomyelinases may contribute to the pathogenesis of infection. Among Leptospira spp., there are five sphingomyelinases exclusively expressed by pathoge
Externí odkaz:
https://doaj.org/article/5a239d73031f46a4bba57576416bc2b8
Autor:
Barbara de Oliveira Baptista, Ana Beatriz Lopes de Souza, Luana Santos de Oliveira, Hugo Amorim dos Santos de Souza, Jenifer Peixoto de Barros, Lucas Tavares de Queiroz, Rodrigo Medeiros de Souza, Linda Eva Amoah, Susheel Kumar Singh, Michael Theisen, Rodrigo Nunes Rodrigues-da-Silva, Evelyn Kety Pratt Riccio, Paulo Renato Rivas Totino, Josué da Costa Lima-Junior, Cláudio Tadeu Daniel-Ribeiro, Lilian Rose Pratt-Riccio
Publikováno v:
Vaccines, Vol 11, Iss 2, p 446 (2023)
The GMZ2.6c malaria vaccine candidate is a multi-stage P. falciparum chimeric protein that contains a fragment of the sexual-stage Pfs48/45-6C protein genetically fused to GMZ2, an asexual-stage vaccine construction consisting of the N-terminal regio
Externí odkaz:
https://doaj.org/article/8501a8e5505541e0829e525f7026017b
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/c57a8f55c4144ad4a0165cc6aa2ae3d8
Autor:
Otto Castro Nogueira, Mariana Gandini, Natasha Cabral, Vilma de Figueiredo, Rodrigo Nunes Rodrigues-da-Silva, Josué da Costa Lima-Junior, Roberta Olmo Pinheiro, Geraldo Moura Batista Pereira, Maria Cristina Vidal Pessolani, Cristiana Santos de Macedo
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Despite being treatable, leprosy still represents a major public health problem, and many mechanisms that drive leprosy immunopathogenesis still need to be elucidated. B cells play important roles in immune defense, being classified in different subg
Externí odkaz:
https://doaj.org/article/e54a798f6bfd4bde8279f649fc62e34b
Autor:
Hugo Amorim dos Santos de Souza, Victor Fernandes Escafa, Carolina Moreira Blanco, Bárbara de Oliveira Baptista, Jenifer Peixoto de Barros, Evelyn Ketty Pratt Riccio, Aline Beatriz Mello Rodrigues, Gisely Cardoso de Melo, Marcus Vinícius Guimarães de Lacerda, Rodrigo Medeiros de Souza, Josué da Costa Lima-Junior, Ana Carolina Ramos Guimarães, Fabio Faria da Mota, João Hermínio Martins da Silva, Cláudio Tadeu Daniel-Ribeiro, Lilian Rose Pratt-Riccio, Paulo Renato Rivas Totino
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 116 (2021)
In the present study, we investigated the genetic diversity of Plasmodium vivax metacaspase 1 (PvMCA1) catalytic domain in two municipalities of the main malaria hotspot in Brazil, i.e., the Juruá Valley, and observed complete sequence identity amon
Externí odkaz:
https://doaj.org/article/786f2a1e08334cd0a75c4a0b425b730f