Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Josmar Salas-Hernández"'
Autor:
Laura Ciuffreda, José M. Lorenzo-Salazar, Diego García-Martínez de Artola, Helena Gil-Campesino, Julia Alcoba-Florez, Héctor Rodríguez-Pérez, Antonio Íñigo-Campos, Josmar Salas-Hernández, Julia Rodríguez-Nuñez, Adrián Muñoz-Barrera, Agustín Valenzuela-Fernández, Oscar Díez-Gil, Rafaela González-Montelongo, Carlos Flores
Publikováno v:
Emerging Microbes and Infections, Vol 12, Iss 1 (2023)
ABSTRACTThe emergence of the Omicron SARS-CoV-2 variant of concern has changed the COVID-19 scenario as this variant is characterized by high transmissibility and immune evasion ability. To evaluate the impact of this variant on the Canary Islands (S
Externí odkaz:
https://doaj.org/article/b927988f0fa748fcb75e935e9b1af6ff
Autor:
Adrián Muñoz-Barrera, Laura Ciuffreda, Julia Alcoba-Florez, Luis A. Rubio-Rodríguez, Héctor Rodríguez-Pérez, Helena Gil-Campesino, Diego García-Martínez de Artola, Josmar Salas-Hernández, Julia Rodríguez-Núñez, Antonio Íñigo-Campos, Víctor García-Olivares, Oscar Díez-Gil, Rafaela González-Montelongo, Agustín Valenzuela-Fernández, José M. Lorenzo-Salazar, Carlos Flores
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 2197-2203 (2023)
On July 23, 2022, monkeypox disease (mpox) was declared a Public Emergency of International Concern (PHEIC) by the World Health Organization (WHO) due to a multicountry outbreak. In Europe, several cases of mpox virus (MPXV) infection related to this
Externí odkaz:
https://doaj.org/article/51086f1e709c4d128c66965fc267d64c
Autor:
Pedro Barroso-Chinea, Ignacio Cruz-Muros, Domingo Afonso-Oramas, Javier Castro-Hernández, Josmar Salas-Hernández, Abdelwahed Chtarto, Diego Luis-Ravelo, Marie Humbert-Claude, Liliane Tenenbaum, Tomás González-Hernández
Publikováno v:
Neurobiology of Disease, Vol 88, Iss , Pp 44-54 (2016)
The dopamine (DA) transporter (DAT) is a plasma membrane glycoprotein expressed in dopaminergic (DA-) cells that takes back DA into presynaptic neurons after its release. DAT dysfunction has been involved in different neuro-psychiatric disorders incl
Externí odkaz:
https://doaj.org/article/e4b338257bdd4dbba1852aa469aa5533
Autor:
Javier Castro-Hernández, Domingo Afonso-Oramas, Ignacio Cruz-Muros, Josmar Salas-Hernández, Pedro Barroso-Chinea, Rosario Moratalla, Mark J. Millan, Tomás González-Hernández
Publikováno v:
Neurobiology of Disease, Vol 74, Iss , Pp 325-335 (2015)
The dopamine (DA) transporter (DAT), a membrane glycoprotein expressed in dopaminergic neurons, clears DA from extracellular space and is regulated by diverse presynaptic proteins like protein kinases, α-synuclein, D2 and D3 autoreceptors. DAT dysfu
Externí odkaz:
https://doaj.org/article/86c1405b04d6459ebf7d6a71220e721d
Autor:
Domingo Afonso-Oramas, Ignacio Cruz-Muros, Pedro Barroso-Chinea, Diego Álvarez de la Rosa, Javier Castro-Hernández, Josmar Salas-Hernández, Teresa Giráldez, Tomás González-Hernández
Publikováno v:
Neurobiology of Disease, Vol 40, Iss 3, Pp 518-530 (2010)
The dopamine transporter (DAT) is a transmembrane glycoprotein responsible for dopamine (DA) uptake, which has been shown to be involved in DA-cell degeneration in Parkinson's disease (PD). At the same time, some studies suggest that DAT may be regul
Externí odkaz:
https://doaj.org/article/8a1ddd039da040858b819440b32ecfaa
Autor:
Domingo Afonso-Oramas, Ignacio Cruz-Muros, Diego Álvarez de la Rosa, Pedro Abreu, Teresa Giráldez, Javier Castro-Hernández, Josmar Salas-Hernández, José L. Lanciego, Manuel Rodríguez, Tomas González-Hernández
Publikováno v:
Neurobiology of Disease, Vol 36, Iss 3, Pp 494-508 (2009)
The dopamine transporter (DAT) is a membrane glycoprotein responsible for dopamine (DA) uptake, which has been involved in the degeneration of DA cells in Parkinson's disease (PD). Given that DAT activity depends on its glycosylation status and membr
Externí odkaz:
https://doaj.org/article/3f9d72e6ec2a4facbb948ef46facb6be
Autor:
Tomás González-Hernández, Ignacio Cruz-Muros, Domingo Afonso-Oramas, Josmar Salas-Hernández, Javier CastroHernández
Publikováno v:
Frontiers in Neuroanatomy, Vol 4 (2010)
The term vulnerability was first associated with the midbrain dopaminergic neurons eighty-five years ago, before they were identified as monoaminergic neurons, when Foix and Nicolesco (1925) reported the loss of neuromelanin containing neurons in the
Externí odkaz:
https://doaj.org/article/c79d68c63bf64228a35abcba87660bcc
Autor:
V. Mesa-Infante, Pedro Barroso-Chinea, Josmar Salas-Hernández, Domingo Afonso-Oramas, Julia Rodriguez-Nuñez
Publikováno v:
Molecular and cellular neurosciences. 118
Glial cell line-derived neurotrophic factor (GDNF) promotes differentiation, proliferation, and survival in different cell types, including dopaminergic neurons. Thus, GDNF has been proposed as a promising neuroprotective therapy in Parkinson's disea
Autor:
Domingo Afonso-Oramas, Rosario Moratalla, Alejandro Febles-Casquero, Pedro Barroso-Chinea, Ignacio Cruz-Muros, Felipe Fumagallo-Reading, Javier Castro-Hernández, Millan Mark, Josmar Salas-Hernández, Diego Luis-Ravelo, Pedro Abreu-Gonzalez, Julia Rodriguez-Nuñez, Tomás González-Hernández
Publikováno v:
Autophagy
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
Growing evidence shows that autophagy is deficient in neurodegenerative and psychiatric diseases, and that its induction may have beneficial effects in these conditions. However, as autophagy shares signaling pathways with cell death and interferes w
Autor:
Julia Rodriguez-Nuñez, Virginia Mesa-Infante, Josmar Salas-Hernández, Alejandro Febles-Casquero, Ignacio Cruz-Muros, Diego Luis-Ravelo, Pedro Barroso-Chinea, Javier Castro-Hernández, Tomás González-Hernández, Domingo Afonso-Oramas, Felipe Fumagallo-Reading
Publikováno v:
Pharmacological Research. 165:105434
The dopamine transporter (DAT) is a membrane glycoprotein in dopaminergic neurons, which modulates extracellular and intracellular dopamine levels. DAT is regulated by different presynaptic proteins, including dopamine D2 (D2R) and D3 (D3R) receptors