Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Joslyn L. Mangal"'
Autor:
Sahil Inamdar, Abhirami P. Suresh, Joslyn L. Mangal, Nathan D. Ng, Alison Sundem, Christopher Wu, Kelly Lintecum, Abhirami Thumsi, Taravat Khodaei, Michelle Halim, Nicole Appel, Madhan Mohan Chandra Sekhar Jaggarapu, Arezoo Esrafili, Jordan R. Yaron, Marion Curtis, Abhinav P. Acharya
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Inhibition of glycolysis in immune cells and cancer cells diminishes their activity, and thus combining immunotherapies with glycolytic inhibitors is challenging. Herein, a strategy is presented where glycolysis is inhibited in cancer cells
Externí odkaz:
https://doaj.org/article/1b742fa55db040f2888e0d48066e3a19
Publikováno v:
Bioengineering & Translational Medicine, Vol 7, Iss 1, Pp n/a-n/a (2022)
Abstract The systemic pharmacotherapeutic efficacy of immunomodulatory drugs is heavily influenced by its route of administration. A few common routes for the systemic delivery of immunotherapeutics are intravenous, intraperitoneal, and intramuscular
Externí odkaz:
https://doaj.org/article/1c51e7f5d2284b66b0b52e770c894238
Autor:
Sahil Inamdar, Abhirami P. Suresh, Joslyn L. Mangal, Nathan D. Ng, Alison Sundem, Hoda Shokrollahzadeh Behbahani, Thomas E. Rubino, Xiaojian Shi, Sharon T. Loa, Jordan R. Yaron, Taro Hitosugi, Matthew Green, Haiwei Gu, Marion Curtis, Abhinav P. Acharya
Publikováno v:
Journal of Controlled Release. 358:541-554
Autor:
Joslyn L. Mangal, Sahil Inamdar, Abhirami P. Suresh, Madhan Mohan Chandra Sekhar Jaggarapu, Arezoo Esrafili, Nathan D. Ng, Abhinav P. Acharya
Publikováno v:
Biomaterials Science. 10:6688-6697
Activated effector T cells induce pro-inflammatory responses in rheumatoid arthritis (RA) which then lead to inflammation of the joints. In this report, we demonstrate that polymeric nanoparticles with alpha keto-glutarate (aKG) in their polymer back
Autor:
Abhirami Thumsi, Srivatsan J. Swaminathan, Joslyn L. Mangal, Abhirami P. Suresh, Abhinav P. Acharya
Publikováno v:
Drug Delivery and Translational Research.
Autor:
Madhan M. C. S. Jaggarapu, Deepanjan Ghosh, Tyler Johnston, Jordan R. Yaron, Joslyn L. Mangal, Sahil Inamdar, Mallikarjun Gosangi, Kaushal Rege, Abhinav P. Acharya
Publikováno v:
Journal of Biomedical Materials Research Part A.
Autor:
Joslyn L. Mangal, Sidnee Mcmillian, Mamta Wankhede, Riccardo Gottardi, Sahil Inamdar, Jamie L Handlos, Abhinav P. Acharya, Arezoo Esrafili
Publikováno v:
Cancers, Vol 13, Iss 1123, p 1123 (2021)
Cancers
Cancers
Simple Summary This review paper here describes the recent progress that has been made in chimeric antigen receptor (CAR) -based therapies for treatment of tumors and the role of metabolism in the tumor microenvironment in relation to these therapies
Autor:
Kaushal Rege, Abhinav P. Acharya, Sahil Inamdar, Subhadeep Dutta, Joslyn L. Mangal, Matthew D. Green, Marion Curtis, Haiwei Gu, Mamta Wankhede, Yi Yang, Xiaojian Shi
Publikováno v:
J Mater Chem B
Metabolites control immune cell functions, and delivery of these metabolites in a sustained manner may be able to modulate function of the immune cells . In this study, alpha-ketoglutarate (aKG) and diol based polymeric-microparticles (termed paKG MP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c12a1c47dd8044ff3130af7f59505d45
https://europepmc.org/articles/PMC8294829/
https://europepmc.org/articles/PMC8294829/