Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Josival Emanuel Ferreira Alves"'
Autor:
Gleyton Leonel Silva Sousa, Thiago da Silva Honório, Priscila de Souza Furtado, Alice Simon, Lucio Mendes Cabral, Gabriel Rodrigues Coutinho Pereira, Josival Emanuel Ferreira Alves, Sinara Mônica Vitalino de Almeida, Valdenizia Rodrigues Silva, Luciano de Souza Santos, Daniel Pereira Bezerra, Rosane Nora Castro, Ricardo Olímpio de Moura, Arthur Eugen Kümmerle
Publikováno v:
Results in Chemistry, Vol 7, Iss , Pp 101371- (2024)
Thiosemicarbazone-acridine hybrids are prominent inhibitors of topoisomerases II. This study reports the design, synthesis, and antiproliferative evaluation of eighteen new acridine–thiosemicarbazone derivatives as possible inhibitors of topoisomer
Externí odkaz:
https://doaj.org/article/a135da7c6124486eb2fa2c1d4a7db52a
Autor:
Keriolaine Lima dos Santos, Sinara Mônica Vitalino de Almeida, Josival Emanuel Ferreira Alves, Iris Trindade Tenório Jacob, Rafael David Souto de Azevedo, Cindy Juliane da Silva Ferreira, Jéssica Celerino dos Santos, Maria do Carmo Alves de Lima, José Cleberson Santos Soares, Amélia Galdino Ribeiro
Publikováno v:
Medicinal Chemistry Research. 30:1469-1495
Albumin is an abundant protein in nature with several biological functions. In the human body, both in health and in illness, its transport function is highlighted by the binding to medicinal drugs and consequent distribution in the bloodstream to th
Autor:
Luiz Bezerra de Carvalho Júnior, Túlio Ricardo Couto de Lima Souza, Ricardo Olímpio de Moura, Josival Emanuel Ferreira Alves, Jamerson Ferreira de Oliveira, Sinara Mônica Vitalino de Almeida, Maria do Carmo Alves de Lima
Publikováno v:
International Journal of Biological Macromolecules. 170:622-635
In this study, we report the synthesis of eight novel indole-thiazole and indole-thiazolidinone derivatives, as well as their ability to interact with DNA, analysed through the UV–vis absorption, fluorescence, circular dichroism (CD), viscosity tec
Autor:
Thais de Freitas Souza, Josival Emanuel Ferreira Alves, Amélia Galdino Ribeiro, Jamerson Ferreira de Oliveira, Luiz Bezerra de Carvalho Júnior, Sinara Mônica Vitalino de Almeida, Ricardo Olímpio de Moura, Maria do Carmo Alves de Lima, Túlio Ricardo Couto de Lima Souza, Francivaldo Araújo da Silva Filho
Publikováno v:
International Journal of Biological Macromolecules. 138:582-589
In the present study, acridine-thiosemicarbazones (ATD) derivatives were tested for their interaction properties with BSA through UV–Vis absorption and fluorescence spectroscopic studies. Both hyperchromic and hypochromic effects, as well as red or
Autor:
Luiz Bezerra de Carvalho Júnior, Sinara Mônica Vitalino de Almeida, Antônio Edson de Souza Lucena, Gleyton Leonel Silva Sousa, Josival Emanuel Ferreira Alves, Aurenice Arruda Dutra das Merces, Rafael David Souto de Azevedo, Maria Luiza Cavalcanti Lucena, Maria do Carmo Alves de Lima, Ricardo Olímpio de Moura
Publikováno v:
International journal of biological macromolecules. 192
This work aimed to develop a simple and low-cost method to obtain human serum albumin (HSA) and its consequent application for in vitro drug interaction assays. The HSA was purified by classic principles of plasma precipitation and thermocoagulation,
Autor:
Amélia Galdino Ribeiro, Maria do Carmo Alves de Lima, Keriolaine Lima dos Santos, Cindy Juliane da Silva Ferreira, José Cleberson Santos Soares, Jamerson Ferreira de Oliveira, Iris Trindade Tenório Jacob, Jéssica Celerino dos Santos, Josival Emanuel Ferreira Alves, Luiz Bezerra de Carvalho Júnior, Sinara Mônica Vitalino de Almeida
Publikováno v:
Bioorganic & Medicinal Chemistry
Graphical abstract
Urgent treatments, in any modality, to fight SARS-CoV-2 infections are desired by society in general, by health professionals, by Estate-leaders and, mainly, by the scientific community, because one thing is certain amidst the
Urgent treatments, in any modality, to fight SARS-CoV-2 infections are desired by society in general, by health professionals, by Estate-leaders and, mainly, by the scientific community, because one thing is certain amidst the
Autor:
Jamerson Ferreira de Oliveira, Josival Emanuel Ferreira Alves, Sinara Mônica Vitalino de Almeida, Amélia Galdino Ribeiro, Maria do Carmo Alves de Lima, Geilza Carla de Lima Silva, Luiz Bezerra de Carvalho, Eduardo Isidoro Carneiro Beltrão
Publikováno v:
Biomedicinepharmacotherapy = Biomedecinepharmacotherapie. 96
DNA is considered one of the most promising targets of molecules with anticancer activity potential. Its key role in various cell division mechanisms, which commands the intense multiplication of tumor cells, is considered in studies with compounds w