Výsledky vyhledávání - "Josipa Skelin"

Akademický článek

Analysis of Primary Chronic Lymphocytic Leukemia Cells’ Signaling Pathways

Autor: Josipa Skelin, Maja Matulić, Lidija Milković, Darko Heckel, Jelena Skoko, Kristina Ana Škreb, Biljana Jelić Puškarić, Ika Kardum-Skelin, Lipa Čičin-Šain, Delfa Radić-Krišto, Mariastefania Antica

Publikováno v: Biomedicines, Vol 12, Iss 3, p 524 (2024)

Chronic lymphocytic leukemia (CLL) is a lymphoproliferative disorder characterized by a specific expansion of mature B-cell clones. We hypothesized that the disease has a heterogeneous clinical outcome that depends on the genes and signaling pathways

Externí odkaz: https://doaj.org/article/bb85a3313e2b4e2a8da98e1fdc05d944

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Akademický článek

Comparative Analysis of Alpha and Beta HPV E6 Oncoproteins: Insights into Functional Distinctions and Divergent Mechanisms of Pathogenesis

Autor: Josipa Skelin, Vjekoslav Tomaić

Publikováno v: Viruses, Vol 15, Iss 11, p 2253 (2023)

Human papillomaviruses (HPVs) represent a diverse group of DNA viruses that infect epithelial cells of mucosal and cutaneous tissues, leading to a wide spectrum of clinical outcomes. Among various HPVs, alpha (α) and beta (β) types have garnered si

Externí odkaz: https://doaj.org/article/a6dc0007cc6c498b920079b25f1b1218

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Akademický článek

HPV16 Impacts NHERF2 Expression in Oropharyngeal Cancers

Autor: Lucija Lulić, Antonia Jakovčević, Iva Kovačić, Luka Manojlović, Emil Dediol, Josipa Skelin, Vjekoslav Tomaić

Publikováno v: Pathogens, Vol 12, Iss 8, p 1013 (2023)

Infection with human papillomaviruses (HPVs), in particular with HPV type 16, is now considered to be a key risk factor for the development of a subset of oropharyngeal squamous cell carcinomas (OPSCC) that show different epidemiological, clinical, a

Externí odkaz: https://doaj.org/article/42a59112cd714136a5d617588071a17a

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Akademický článek

Do or Die: HPV E5, E6 and E7 in Cell Death Evasion

Autor: Josipa Skelin, Ivan Sabol, Vjekoslav Tomaić

Publikováno v: Pathogens, Vol 11, Iss 9, p 1027 (2022)

Human papillomaviruses (HPVs) infect the dividing cells of human epithelia and hijack the cellular replication machinery to ensure their own propagation. In the effort to adapt the cell to suit their own reproductive needs, the virus changes a number

Externí odkaz: https://doaj.org/article/19dbdf5e9477479a9537486b5329960e

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Akademický článek

Notch pathway connections in primary leukaemia samples of limited size

Autor: Luka Horvat, Josipa Skelin, Biljana Jelić Puškarić, Isidoro Feliciello, Darko Heckel, Josip Madunić, Ika Kardum-Skelin, Maja Matulić, Delfa Radić-Krišto, Mariastefania Antica

Publikováno v: Translational Medicine Communications, Vol 3, Iss 1, Pp 1-9 (2018)

Abstract Background The Notch pathway combined with other signalling molecules acts specifically for the development of each blood cell type and differentiation stage. A causative role of Notch dysfunction in leukaemia development has been found in m

Externí odkaz: https://doaj.org/article/504e88bf4ee342458df3787e423f01a0

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Akademický článek

Human Papillomaviruses-Associated Cancers: An Update of Current Knowledge

Autor: Ena Pešut, Anamaria Đukić, Lucija Lulić, Josipa Skelin, Ivana Šimić, Nina Milutin Gašperov, Vjekoslav Tomaić, Ivan Sabol, Magdalena Grce

Publikováno v: Viruses, Vol 13, Iss 11, p 2234 (2021)

Human papillomaviruses (HPVs), which are small, double-stranded, circular DNA viruses infecting human epithelial cells, are associated with various benign and malignant lesions of mucosa and skin. Intensive research on the oncogenic potential of HPVs

Externí odkaz: https://doaj.org/article/4a207d0516cb4b708d43cf68ad57bccd

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Akademický článek

HPV Oncoproteins and the Ubiquitin Proteasome System: A Signature of Malignancy?

Autor: Anamaria Đukić, Lucija Lulić, Miranda Thomas, Josipa Skelin, Nathaniel Edward Bennett Saidu, Magdalena Grce, Lawrence Banks, Vjekoslav Tomaić

Publikováno v: Pathogens, Vol 9, Iss 2, p 133 (2020)

Human papillomavirus (HPV) E6 and E7 oncoproteins are critical for development and maintenance of the malignant phenotype in HPV-induced cancers. These two viral oncoproteins interfere with a plethora of cellular pathways, including the regulation of

Externí odkaz: https://doaj.org/article/5619f70345ea4145832383218770d180

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