Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Josip Peradinovic"'
Autor:
Nikolina Mohovic, Josip Peradinovic, Andrea Markovinovic, Raffaello Cimbro, Zeljka Minic, Marin Dominovic, Hrvoje Jakovac, Jerneja Nimac, Boris Rogelj, Ivana Munitic
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Optineurin is a multifunctional polyubiquitin-binding protein implicated in inflammatory signalling. Optineurin mutations are associated with amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), neurodegenerative diseases c
Externí odkaz:
https://doaj.org/article/cf99c315ffd74886bc68a751d0a87349
Autor:
Josip Peradinovic, Nikolina Mohovic, Katarina Bulic, Andrea Markovinovic, Raffaello Cimbro, Ivana Munitic
Publikováno v:
Biology, Vol 12, Iss 2, p 240 (2023)
Optineurin is a ubiquitin-binding adaptor protein involved in multiple cellular processes, including innate inflammatory signalling. Mutations in optineurin were found in amyotrophic lateral sclerosis, an adult-onset fatal neurodegenerative disease t
Externí odkaz:
https://doaj.org/article/de6aa34ca0474e9ca64173f7c5b97699
Autor:
Marin Dominovic, Josip Peradinovic, Rozalija Šajn, Ivana Munitic, Andrea Markovinovic, Nikolina Prtenjaca
Publikováno v:
Periodicum biologorum
Volume 121-122
Issue 1-2
Volume 121-122
Issue 1-2
Mutations in optineurin have been linked to amyotrophic lateral sclero- sis (ALS) a decade ago, but its exact role in the neurodegenerative process is still unclear. As a lysine 63 (K63)- and methionine (M1)-linked polyubiq- uitin-binding protein, op
Publikováno v:
The Journal of Immunology. 206:52.22-52.22
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease marked by protein aggregation and neuroinflammation. Protein aggregates in >95% of ALS cases are cytoplasmic and contain ubiquitinated and phosphorylated TAR DNA binding protein 43 kD