Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Josine Van Beek"'
Autor:
Marieke van der Heiden, Sudarshan Shetty, Elske Bijvank, Lisa Beckers, Alper Cevirgel, Yannick van Sleen, Irina Tcherniaeva, Thierry Ollinger, Wivine Burny, Rob S. van Binnendijk, Marianne A. van Houten, Anne-Marie Buisman, Nynke Y. Rots, Josine van Beek, Debbie van Baarle
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Vaccine responsiveness is often reduced in older adults. Yet, our lack of understanding of low vaccine responsiveness hampers the development of effective vaccination strategies to reduce the impact of infectious diseases in the ageing popul
Externí odkaz:
https://doaj.org/article/06046bf390ae45ecba7a7f99b04e98c1
Autor:
Martijn D. B. Van de Garde, Alberto Miranda-Bedate, Nening M. Nanlohy, Ronald H. J. Jacobi, Adam Meijer, Daphne F. M. Reukers, Josine Van Beek, Cecile A. C. M. Van Els, Debbie Van Baarle, Nynke Y. Rots, Jelle De Wit, Elena Pinelli
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundTo date, it is still not clear why during the COVID-19 pandemic children generally developed no or milder symptoms compared to adults. As innate immune responses are crucial in the early defense against pathogens, we aimed at profiling thes
Externí odkaz:
https://doaj.org/article/a4688d1db3db4bf3bf5ffc3c63bbfd79
Autor:
Alper Cevirgel, Martijn Vos, Anne Floor Holtrop, Lisa Beckers, Daphne F. M. Reukers, Adam Meijer, Nynke Rots, Josine van Beek, Debbie van Baarle, Jelle de Wit
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract The SARS-CoV-2 pandemic has emphasized the need to explore how variations in the immune system relate to the severity of the disease. This study aimed to explore inter-individual variation in response to SARS-CoV-2 infection by comparing T c
Externí odkaz:
https://doaj.org/article/31977c7592c542599d161f7380b86e33
Autor:
Jolanda Brummelman, Sara Suárez-Hernández, Lia de Rond, Marjan Bogaard-van Maurik, Petra Molenaar, Emma van Wijlen, Debbie Oomen, Lisa Beckers, Nynke Y. Rots, Josine van Beek, Mioara A. Nicolaie, Cécile A. C. M. van Els, Mardi C. Boer, Patricia Kaaijk, Anne-Marie Buisman, Jelle de Wit
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionAccumulating evidence indicates the importance of T cell immunity in vaccination-induced protection against severe COVID-19 disease, especially against SARS-CoV-2 Variants-of-Concern (VOCs) that more readily escape from recognition by neu
Externí odkaz:
https://doaj.org/article/cf79c091b63b4b60b5a6577f4427f37e
Autor:
Yannick van Sleen, Sudarshan A. Shetty, Marieke van der Heiden, Milou C. A. Venema, Nicolas Gutiérrez-Melo, Erik J. M. Toonen, Josine van Beek, Anne-Marie Buisman, Debbie van Baarle, Delphine Sauce
Publikováno v:
Immunity & Ageing, Vol 20, Iss 1, Pp 1-13 (2023)
Abstract Frailty describes an age-associated state in individuals with an increased vulnerability and less resilience against adverse outcomes. To score frailty, studies have employed the questionnaires, such as the SF-36 and EQ-5D-3L, or the Frailty
Externí odkaz:
https://doaj.org/article/b25c25b4aa7f44a7a9da0c8f91b279d0
Autor:
Quincy Hofsink, Sabine Haggenburg, Birgit I. Lissenberg-Witte, Annoek E.C. Broers, Jaap A. van Doesum, Rob S. van Binnendijk, Gerco den Hartog, Michel S. Bhoekhan, Nienke J.E. Haverkate, Johan van Meerloo, Judith A. Burger, Joey H. Bouhuijs, Gaby P. Smits, Dorine Wouters, Ester M.M. van Leeuwen, Hetty J. Bontkes, Neeltje A. Kootstra, Sandra Vogels-Nooijen, Nynke Rots, Josine van Beek, Mirjam H.M. Heemskerk, Kazimierz Groen, Tom van Meerten, Pim G.N.J. Mutsaers, Marit J. van Gils, Abraham Goorhuis, Caroline E. Rutten, Mette D. Hazenberg, Inger S. Nijhof, Iris M.J. Kant, Thecla Graas, Belle Toussaint, Sterre de Jong, Shahan Darwesh, Sandjiv S. Mahes, Dora Kamminga, Matthijs Koelewijn, Gino Faber, Guus Beaumont, Marije D. Engel, R. Cheyenne N. Pierie, Suzanne R. Janssen, Edith van Dijkman, Jarom Heijmans, Yara Y. Witte, Rogers A. Nahui Palomino, Said Z. Omar, Sonja Zweegman, Arnon P. Kater, Caya van den Vegt, Ilonka Arends-Halbesma, Emma de Pater, Margriet J. Dijkstra, Nynke Y. Rots, Esther Siteur-van Rijnstra, Dennis M. de Rooij, Rogier W. Sanders, Meliawati Poniman, Wouter Olijhoek, Jacqueline van Rijswijk, Tim Beaumont, Lusia Çetinel, Louis Schellekens, Yvonne M. den Hartogh, Jacqueline Cloos, Suzanne S. Weijers, Saïda Tonouh-Aajoud, Selime Avci, Elianne Roelandse-Koop, Willem A. Dik
Publikováno v:
EClinicalMedicine, Vol 61, Iss , Pp 102040- (2023)
Summary: Background: Patients with haematological malignancies have impaired antibody responses to SARS-CoV-2 vaccination. We aimed to investigate whether a fourth mRNA COVID-19 vaccination improved antibody quantity and quality. Methods: In this coh
Externí odkaz:
https://doaj.org/article/b6705aeb989e44eeb7ee10f048616947
Autor:
Marije K. Verheul, Marion Hendriks, Caroline Vilas Boas de Melo, Sophie van Tol, Gert-Jan Godeke, Rob van Binnendijk, Willem Luytjes, Chantal Reusken, Josine van Beek
Publikováno v:
Frontiers in Virology, Vol 3 (2023)
IntroductionRespiratory infections are a common cause of illness in older adults, potentially resulting in severe morbidity or mortality. While up to 10% of respiratory infections in this population are caused by one of the four human coronaviruses (
Externí odkaz:
https://doaj.org/article/924b9000af794be2be1c647ae790f383
Autor:
Sudarshan A. Shetty, Josine van Beek, Elske Bijvank, James Groot, Sjoerd Kuiling, Thijs Bosch, Debbie van Baarle, Susana Fuentes
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Influenza-like illness (ILI), a disease caused by respiratory pathogens including influenza virus, is a major health concern in older adults. There is little information on changes and recovery dynamics of the nasopharyngeal (NP) microbiota
Externí odkaz:
https://doaj.org/article/8c67a678e7d34ef2b339fa4666b54610
Autor:
Marije K. Verheul, Kim H. Nijhof, Mary-lène de Zeeuw-Brouwer, Geraly Duijm, Hinke ten Hulscher, Lia de Rond, Lisa Beckers, Dirk Eggink, Sophie van Tol, Johan Reimerink, Mardi Boer, Josine van Beek, Nynke Rots, Rob van Binnendijk, Anne-Marie Buisman
Publikováno v:
Vaccines, Vol 11, Iss 7, p 1196 (2023)
The generation of a specific long-term immune response to SARS-CoV-2 is considered important for protection against COVID-19 infection and disease. Memory B cells, responsible for the generation of antibody-producing plasmablasts upon a new antigen e
Externí odkaz:
https://doaj.org/article/a48f77bf528d4fd69ee4ff2c341e3b9e
Autor:
Daan K. J. Pieren, Noortje A. M. Smits, Rimke J. Postel, Vinitha Kandiah, Jelle de Wit, Josine van Beek, Debbie van Baarle, Teun Guichelaar
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Aging leads to alterations in the immune system that result in ineffective responsiveness against pathogens. Features of this process, collectively known as immunosenescence, accumulate in CD8+ T cells with age and have been ascribed to differentiati
Externí odkaz:
https://doaj.org/article/540cc8eee72e4f82b5946a757d75dc86