Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Josine S. Quaedackers"'
Autor:
Christopher A. Lear, Robert Galinsky, Paul P. Drury, Alistair J. Gunn, Georgia R Mackay, Joanne O. Davidson, Laura Bennet, Josine S. Quaedackers
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 38:706-718
Antenatal glucocorticoid therapy significantly improves the short-term systemic outcomes of prematurely born infants, but there is limited information available on their impact on neurodevelopmental outcomes in at-risk preterm babies exposed to perin
Autor:
Miriam E. Koome, Josine S. Quaedackers, Joanne O. Davidson, Robert Galinsky, Alistair J. Gunn, Laura Bennet, Paul P. Drury, Christopher A. Lear
Publikováno v:
The Journal of Physiology. 592:5493-5505
Exposure to clinical doses of the glucocorticoid dexamethasone increases brain activity and causes seizures in normoxic preterm fetal sheep without causing brain injury. In contrast, the same treatment after asphyxia increased brain injury. We hypoth
Preterm neonatal cardiovascular instability: Does understanding the fetus help evaluate the newborn?
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 39:965-972
Preterm newborns, particularly very low birth weight newborns, frequently experience intermittent hypotension and/or hypoperfusion. Organ perfusion is largely distinct from systemic hypotension, suggesting that changes in underlying vascular tone are
Publikováno v:
The Journal of Physiology. 589:3823-3835
Maternal treatment with synthetic corticosteroids such as dexamethasone (DEX)significantly reduces neonatal morbidity and mortality, but its effects on the fetal brain remain unclear. In this study we evaluated the effects of DEX on EEG activity in p
Publikováno v:
The Journal of Physiology. 572:141-154
Early onset cerebral hypoperfusion after birth is highly correlated with neurological injury in premature infants, but the relationship with the evolution of injury remains unclear. We studied changes in cerebral oxygenation, and cytochrome oxidase (
Publikováno v:
Experimental Physiology. 90:545-555
It has been hypothesized that the hypothalamic-pituitary-adrenal (HPA) axis is immature in the preterm fetus and that this compromises their ability to adapt to hypoxic stress; however, there are few direct data. We therefore examined the effects of
Publikováno v:
BJOG: An International Journal of Obstetrics and Gynaecology. 112:182-191
Objective To determine the effects of a single course of maternally administered dexamethasone on preterm fetal sheep in utero. Design Prospective randomised controlled trial. Setting University laboratory. Sample Pregnant sheep at 0.7 of gestation.
Publikováno v:
The Journal of Physiology. 557:1033-1044
Asphyxia in utero in pre-term fetuses is associated with evolving hypoperfusion of the gut after the insult. We examined the role of the sympathetic nervous system (SNS) in mediating this secondary hypoperfusion. Gut blood flow changes were also asse
Publikováno v:
Developmental Neuroscience, 23(3), 175-179. Karger
The premature fetus: not as defenseless as we thought, but still paradoxically vulnerable?Gunn AJ, Quaedackers JS, Guan J, Heineman E, Bennet L.Liggins Institute and Department of Pediatrics, University of Auckland, New Zealand. aj.gunn@auckland.ac.n
Autor:
Philippe Evrard, Michael J. Romanko, Frances J. Northington, Teresa L. Wood, Henrik Hagberg, Susan J. Vannucci, Gorm Greisen, Benjamin Dickens, Céline Dubé, Jian Guan, Malgorzata Puka-Sundvall, Eric Gilland, E. Heineman, Roland L. Meyers, Steven W. Levison, Astrid Nehlig, Maria José da Silva Fernandes, James M. Williams, Alistair J. Gunn, Audrey Foster-Barber, Surya M. Nauli, Matthew J. Snyder, Donna M. Ferriero, Rastafa Geddes, Lee J. Martin, William J. Pearce, Raymond P. Rothstein, Klaus Børch, Josine S. Quaedackers, Laura Bennet, Robert C. Vannucci, Jennifer K. Ness
Publikováno v:
Developmental Neuroscience. 23:248-260