Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Josie Han, Lee"'
Autor:
Peter Yakowec, Jin Tang, Violeta Yu, Alexander M. Long, Ralf Schwandner, Tanja Fisch, Josie Han Lee, Renee Emkey, Markus Hierl, Hao Chen
Publikováno v:
SLAS Discovery. 17:27-38
Lysine demethylase 1 (LSD1) and Jumonji C domain-containing oxygenase D2C (JMJD2C) participate in regulating the methylation status of histone H3 lysine residues. In some contexts, LSD1 and JMJD2C activity causes enhanced cellular proliferation, whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c215ec6a75a7c52375efa2d47a93203f
https://doi.org/10.1177/1087057111418228
https://doi.org/10.1177/1087057111418228
Autor:
Ryan White, James Brown, Jean-Christophe Harmange, Xiaoyang Xia, Josie Han Lee, Yuan Cheng, Robert T. Fremeau, Beth J. Hoffman, Susan A. Tomlinson, Matthew W. Martin, Liyue Huang, Erin F. DiMauro, Stephen Hitchcock, Hung Q. Nguyen, John L. Buchanan, Vinod F. Patel, Ming Huang, William H. Buckner, Brian K. Albrecht, Fen-Fen Lin, Renee Emkey
Publikováno v:
Journal of Medicinal Chemistry. 51:5019-5034
The CB2 receptor is an attractive therapeutic target for analgesic and anti-inflammatory agents. Herein we describe the discovery of a novel class of oxadiazole derivatives from which potent and selective CB2 agonist leads were developed. Initial hit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0c877b87d7688ce77fe355980c89db7
https://doi.org/10.1021/jm800463f
https://doi.org/10.1021/jm800463f
Publikováno v:
Transplantation. 76:1615-1622
Background. CD56 + human natural killer (NK) cells are the principal anti-pig cytotoxic effectors in vitro. Expression of certain human leukocyte antigen (HLA) class I molecules in porcine cells can inhibit NK cell-mediated natural cytotoxicity in se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29593c2968d55e2de5b9450c98cd41a6
https://doi.org/10.1097/01.tp.0000086342.60603.c2
https://doi.org/10.1097/01.tp.0000086342.60603.c2
Autor:
Bee-Chun Sun, Renee Emkey, Ivonne Archibeque, Laurie B. Schenkel, Liqin Liu, Josie Han Lee, Violeta Yu, Stephanie D. Geuns-Meyer, Jeanne Pistillo
Publikováno v:
Experimental hematology. 41(5)
Small molecule inhibitors of Janus kinase (JAK) family members (JAK1, JAK2, JAK3, and Tyk2) are currently being pursued as potential new modes of therapy for a variety of diseases, including the inhibition of JAK2 for the treatment of myeloproliferat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f8bef17a7c8945d061c546456a7c0b3
https://pubmed.ncbi.nlm.nih.gov/23340136
https://pubmed.ncbi.nlm.nih.gov/23340136
Publikováno v:
Transplantation. 76(11)
CD56+ human natural killer (NK) cells are the principal anti-pig cytotoxic effectors in vitro. Expression of certain human leukocyte antigen (HLA) class I molecules in porcine cells can inhibit NK cell-mediated natural cytotoxicity in serum-free medi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::35d80fdcaf4c8ba4d3da73d8aa7d4e50
https://pubmed.ncbi.nlm.nih.gov/14702534
https://pubmed.ncbi.nlm.nih.gov/14702534
Autor:
Gerald L. Waneck, Alexandra F. Sharland, Susan L. Saidman, Aimee E. Cestra, Amy Patel, Josie Han Lee
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 168(7)
Human NK cells are likely to be important effectors of xenograft rejection. Expression of HLA class I molecules by transfected porcine cells can protect them from human NK cell-mediated lysis; however, this strategy has the potential to augment the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a5ca046110add340592d53bd8ac04cd
https://pubmed.ncbi.nlm.nih.gov/11907081
https://pubmed.ncbi.nlm.nih.gov/11907081
Autor:
Yuan Cheng, Brian K. Albrecht, James Brown, John L. Buchanan, William H. Buckner, Erin F. DiMauro, Renee Emkey, Robert T. Fremeau Jr., Jean-Christophe Harmange, Beth J. Hoffman, Liyue Huang, Ming Huang, Josie Han Lee, Fen-Fen Lin, Matthew W. Martin, Hung Q. Nguyen, Vinod F. Patel, Susan A. Tomlinson, Ryan D. White, Xiaoyang Xia
Publikováno v:
Journal of Medicinal Chemistry; Jul2008, Vol. 51 Issue 16, p5019-5034, 16p