Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Josias, Hamman"'
Publikováno v:
Future Journal of Pharmaceutical Sciences, Vol 10, Iss 1, Pp 1-18 (2024)
Abstract Background Curcumin is a compound that occurs in the rhizomes of the turmeric plant (Curcuma longa) and has shown potential for the treatment of illnesses including certain neurodegenerative diseases. The bioavailability of curcumin is hinde
Externí odkaz:
https://doaj.org/article/82848fd52926420c9d6dad2069bf20ee
Autor:
Dallas J. Smith, Huichang Bi, Josias Hamman, Xiaochao Ma, Constance Mitchell, Kumbukani Nyirenda, Tsitsi Monera-Penduka, Hellen Oketch-Rabah, Mary F. Paine, Syril Pettit, Wihan Pheiffer, Richard B. Van Breemen, Michelle Embry
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
The COVID-19 pandemic sparked the development of novel anti-viral drugs that have shown to be effective in reducing both fatality and hospitalization rates in patients with elevated risk for COVID-19 related morbidity or mortality. Currently, nirmatr
Externí odkaz:
https://doaj.org/article/2c10c122871b4cbd8f121c7cf1e9f346
Publikováno v:
Journal of HerbMed Pharmacology, Vol 11, Iss 1, Pp 121-130 (2022)
Introduction: There is growing concern that co-administered herbal medicines may alter the pharmacokinetics and, therefore, the efficacy and toxicity of Western drugs. The aim of this study was to investigate the potential membrane permeation modulat
Externí odkaz:
https://doaj.org/article/c4b28cc6e93643a18e719932d490ce3e
Publikováno v:
Pharmaceutics, Vol 15, Iss 5, p 1423 (2023)
The intranasal route of drug administration offers an opportunity to bypass the blood–brain barrier and deliver compounds directly into the brain. Scientific evidence exists for medicinal plants (e.g., Centella asiatica and Mesembryanthemum tortuos
Externí odkaz:
https://doaj.org/article/867d36b9dd0e459a9282d174e59bfffa
Autor:
Cassandra Kirby-Smith, Jan Steenekamp, Dewald Steyn, Anja Haasbroek-Pheiffer, Hannlie Hamman, Josias Hamman
Publikováno v:
Applied Sciences, Vol 13, Iss 8, p 4822 (2023)
Aloe vera gel and whole leaf materials, as well as polysaccharides, precipitated from the gel, have previously been shown to enhance macromolecular drug delivery across epithelial tissues. This study investigated the effectiveness of microparticle fo
Externí odkaz:
https://doaj.org/article/f5a2638c33ee4c45b6edadcb68f1b88b
Publikováno v:
Journal of HerbMed Pharmacology, Vol 9, Iss 4, Pp 355-365 (2020)
Introduction: The nasal route of drug administration offers an alternative way for oral drug delivery and has the benefit of avoiding first-pass metabolism through drug delivery directly into the systemic circulation. The drug absorption enhancing ef
Externí odkaz:
https://doaj.org/article/e13dcc3702644dc78355bb996c77b280
Autor:
Anri Hattingh, Jean-Pierre Laux, Clarissa Willers, Josias Hamman, Dewald Steyn, Hannlie Hamman
Publikováno v:
South African Journal of Botany. 158:254-264
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e076636630f99c8392fc46d58cf45be2
https://doi.org/10.1016/j.sajb.2023.05.020
https://doi.org/10.1016/j.sajb.2023.05.020
Autor:
Anja Haasbroek‐Pheiffer, Suzanne Van Niekerk, Frank Van der Kooy, Theunis Cloete, Jan Steenekamp, Josias Hamman
Publikováno v:
Biopharmaceutics & Drug Disposition. 44:94-112
The intranasal route of administration provides a noninvasive method to deliver drugs into the systemic circulation and/or directly into the brain. Direct nose‐to‐ brain drug delivery offers the possibility to treat central nervous system disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20bc77e734fc55e8492694dfb192b753
https://doi.org/10.1002/bdd.2348
https://doi.org/10.1002/bdd.2348
Publikováno v:
Pharmaceutics, Vol 12, Iss 5, p 393 (2020)
Many active pharmaceutical ingredients (APIs) exhibit poor solubility and low dissolution rates in aqueous environments such as the luminal fluids of the gastrointestinal tract. The oral bioavailability of these compounds is usually very low as a res
Externí odkaz:
https://doaj.org/article/0e6e9a88da444419a2c237f084423f30
Autor:
Carlemi Calitz, Chrisna Gouws, Joe Viljoen, Jan Steenekamp, Lubbe Wiesner, Efrem Abay, Josias Hamman
Publikováno v:
Molecules, Vol 20, Iss 12, Pp 22113-22127 (2015)
Patients receiving anti-retroviral drug treatment are sometimes simultaneously taking herbal remedies, which may result in pharmacokinetic herb-drug interactions. This study aimed to determine if pharmacokinetic interactions exist between selected co
Externí odkaz:
https://doaj.org/article/9e8a240bd99b49229b1d3eea42216878