Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Josiane Smith"'
Autor:
Jean-Jacques Meister, Boris Hinz, Franco Klingberg, David Ramonet, Aurélie Formey, Lara Buscemi, Josiane Smith-Clerc
Publikováno v:
Current Biology. 21:2046-2054
Summary Background TGF-β1 controls many pathophysiological processes including tissue homeostasis, fibrosis, and cancer progression. Together with its latency-associated peptide (LAP), TGF-β1 binds to the latent TGF-β1-binding protein-1 (LTBP-1),
Publikováno v:
Europe PubMed Central
Overproduction of nitric oxide (NO) upon expression of inducible NO synthase (iNOS) may be responsible for refractory hypotension in septic shock. Whereas high levels of NOS activity have been documented in experimental models of endotoxemia or intra
The nano-scale mechanical properties of the extracellular matrix regulate dermal fibroblast function
Autor:
Heike Diekmann, Volker Achterberg, Horst Wenck, Stefan Gallinat, Jean-Jacques Meister, Josiane Smith-Clerc, Helge Schwengler, Lara Buscemi, Boris Hinz
Publikováno v:
The Journal of investigative dermatology. 134(7)
Changes in the mechanical properties of dermis occur during skin aging or tissue remodeling and affect the activity of resident fibroblasts. With the aim to establish elastic culture substrates that reproduce the variable softness of dermis, we deter
Autor:
Yolande Buchmüller-Rouiller, Pascal Schneider, Josiane Smith, C. Victor Jongeneel, Sally Betz Corradin, Jacques Mauël, Adriana Ransijn
Publikováno v:
Cellular Immunology. 164:73-80
We have examined the effects of two agents depleting the intracellular pool of glutathione (GSH) on macrophage activation induced by IFN-gamma + LPS, as measured by nitrite production and leishmanicidal activity. Diethylmaleate (DEM), which depletes
Publikováno v:
Biochemical Journal. 301:243-247
We examined the effect of bafilomycin A1 (BAF), an inhibitor of vacuolar-type H(+)-ATPases, on macrophages activation (measured as increased nitrite production and leishmanicidal activity) induced by interferon gamma alone or together with lipopolysa
Autor:
Jacques Mauël, Philippe Gallay, Michel P. Glauser, Josiane Smith, Sally Betz Corradin, Didier Heumann
Publikováno v:
Journal of Infectious Diseases, vol. 169, no. 1, pp. 105-111
A recombinant (r) NH2-terminal fragment of bactericidal/permeability-increasing protein, rBPI23, was shown to inhibit murine macrophage nitric oxide (NO) production elicited by lipopolysaccharide (LPS) plus interferon-gamma (IFN-gamma). Normal mouse
Publikováno v:
A30. NOVEL MECHANISMS OF AIRWAY SMOOTH MUSCLE CONTRACTION AND RELAXATION: ARE THESE THERAPEUTICALLY TARGETABLE?.
Transforming growth factor β1 regulation of macrophage activation depends on the triggering stimulus
Publikováno v:
Journal of Leukocyte Biology. 54:423-429
We have examined the effects of transforming growth factor beta 1 (TGF-beta 1) on the regulation of murine bone marrow-derived macrophage function. TGF-beta, added simultaneously with or up to 4 h before interferon-gamma (IFN-gamma) plus lipopolysacc
Autor:
Josiane Smith, Nicolas Fasel, Adriana Ransijn, Jacques Mauël, Yolande Buchmüller-Rouiller, Sally Betz Corradin
Publikováno v:
European Journal of Immunology. 23:2045-2048
Interleukin-10 (IL-10) has been reported to inhibit nitric oxide (NO) synthesis and microbicidal activity of interferon-gamma (IFN-gamma)-stimulated macrophages (M phi) by preventing the secretion of tumor necrosis factor-alpha (TNF-alpha) which serv
Autor:
Yolande Buchmüller-Rouiller, Josiane Smith, Jacques Mauël, Pascal Schneider, Sally Betz-Corradin
Publikováno v:
Biochemical and Biophysical Research Communications. 183:150-155
Murine macrophages activated by interferon-γ and lipopolysaccharide become leishmanicidal through a process involving L-arginine-derived nitrogen oxidation products. Both nitrite secretion and parasite killing by activated macrophages were inhibited