Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Josiane Pierre"'
Autor:
Muriel D. David, Mélanie Polrot, Josiane Pierre, Jacques Bertoglio, Martine Letourneur, Vladimir Lazar, Serge Roche, Jack-Michel Renoir, Philippe Dessen, Cécile Naudin
Publikováno v:
Molecular Oncology. 8:942-955
Suppressor of cytokine signaling (SOCS) 1 is an inducible negative regulator of cytokine signaling but its role in human cancer is not completely established. Here we report that, while SOCS1 is expressed in normal colonic epithelium and colon adenoc
Publikováno v:
Biochemical Pharmacology. 78:1017-1025
Human enhancer of filamentation 1 (HEF1) is a multi-domain docking protein of the p130 Cas family. HEF1 is present at focal adhesions and is involved in integrin signalling mediating cytoskeleton reorganization associated with cell migration, adhesio
Autor:
Anne-Sophie Bats, Xavier Coumoul, Monique Diry, Michèle Garlatti, C. Transy, Aline Chevallier, Céline Tomkiewicz, Stéphane Pierre, J Raingeaud, S Mota, Robert Barouki, Josiane Pierre, Linh-Chi Bui
Publikováno v:
Oncogene. 28:3642-3651
Aryl hydrocarbon receptor (AhR), or dioxin receptor, is a transcription factor that induces adaptive metabolic pathways in response to environmental pollutants. Recently, other pathways were found to be altered by AhR and its ligands. Indeed, develop
Publikováno v:
Oncogene. 22:3386-3394
Interleukin (IL)-4 and IL-13 are two structurally and functionally related cytokines that have overlapping but also distinct biological activities. One of the components of the IL-13 receptor, the alpha2 chain (IL-13Ralpha2), has been reported to dow
Publikováno v:
Oncogene. 19:1596-1604
The stress-activated pathways leading to activation of p38 MAP kinase (p38 MAPK) and c-jun N-terminal kinases (JNK) have been shown to be activated by pro-inflammatory cytokines, physical and chemical stresses as well as a variety of hematopoietic gr
Autor:
Anne Carbonne, Elisabeth Bouvet, Marie-Jeanne Kosmann, Jean-Christophe Lucet, Ljiljana Denic, Josiane Pierre, Claude Deblangy
Publikováno v:
European Journal of Epidemiology. 14:339-342
The aim of this study was to evaluate completeness of tuberculosis notification in Bichat Claude-Bernard University Hospital and to evaluate whether misclassification of atypical mycobacterial infection could have contributed to the inaccuracy of tub
Autor:
Jean-Pierre Liautard, Robert Zumbihl, Bruno Rouot, Josiane Pierre, Sören Schubert, Andreas Roggenkamp, Jan Machold, Klaus Ruckdeschel, Jürgen Heesemann
Publikováno v:
Journal of Biological Chemistry. 272:15920-15927
The enteropathogenic bacterium Yersinia enterocolitica counteracts host defense mechanisms by interfering with eukaryotic signal transduction pathways. In this study, we investigated the mechanism by which Y. enterocoliticaprevents macrophage tumor n
Publikováno v:
Biochemical Pharmacology. 53:287-298
Tyrphostins are synthetic compounds that have been described as in vitro inhibitors of epidermal growth factor receptor (EGF-R) tyrosine kinase activity. The inhibitory effect of tyrphostins in intact cells has been shown only after prolonged treatme
Autor:
Serge Roche, Julie Pannequin, Cédric Leroy, Frédéric Hollande, Jean-François Bourgaux, Audrey Sirvent, Romain M. Larive, Josiane Pierre, Cécile Naudin, Bruno Robert, Valérie Simon
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2014, 5, pp.3159. ⟨10.1038/ncomms4159⟩
Nature Communications, 2014, 5, pp.3159. ⟨10.1038/ncomms4159⟩
Nature Communications, Nature Publishing Group, 2014, 5, pp.3159. ⟨10.1038/ncomms4159⟩
Nature Communications, 2014, 5, pp.3159. ⟨10.1038/ncomms4159⟩
International audience; The adaptor SLAP is a negative regulator of receptor signalling in immune cells but its role in human cancer is ill defined. Here we report that SLAP is abundantly expressed in healthy epithelial intestine but strongly downreg
Autor:
Michel A. Slama, Philippe Giral, Rachel Rosenzweig, Olivier Lortholary, Michel E. Safar, Josiane Pierre, Jacques F. Acar, Laurent Gutmann, Annie Buu Hoï, Jean-Yves Fagon
Publikováno v:
Clinical Infectious Diseases. 20:790-796
To identify risk factors for and prognostic indicators of the nosocomial acquisition of multiresistant Acinetobacter baumannii in an intensive care unit, we prospectively studied 40 patients: 13 who were infected with this organism and 27 who were co