Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Josiane P. Lafleur"'
Publikováno v:
ACS Sensors. 8:1462-1470
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20bd200f9e5409a4ba9c32ca52a57718
https://doi.org/10.1021/acssensors.2c02435
https://doi.org/10.1021/acssensors.2c02435
Autor:
Jacek Majewski, Susie Brousse, Josee-Anne Roy, Cristiano Ferrario, Manuela Pelmus, Najmeh Alirezaie, Catalin Mihalcioiu, Cathy Lan, Talia Roseshter, Adriana Aguilar-Mahecha, Eric Bareke, Mohammed Aldamry, Luca Cavallone, Mark Basik, Josiane P. Lafleur, S. Hassan, André Robidoux, Elizabeth A. Marcus, Carole Seguin, Federico Discepola
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Response to neoadjuvant chemotherapy (NAC) in triple negative breast cancer (TNBC) is highly prognostic and determines whether adjuvant chemotherapy is needed if residual tumor is found at surgery. To evaluate the predictive and prognostic values of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dcb35bf43cf24e44395915c566038fa
http://europepmc.org/articles/PMC7477566
http://europepmc.org/articles/PMC7477566
Autor:
Matthew Dankner, Leah Liu, Atilla Omeroglu, Morag Park, Matthew G. Annis, Sohrab P. Shah, Samuel Aparicio, Nathaniel Bouganim, Paul Savage, Hong Zhao, Valentina Munoz-Ramos, Anie Monast, Kevin Petrecca, Virginie Pilon, Daniel Lai, Josiane P. Lafleur, Peter M. Siegel, Mark Basik, Adrian Wan, Adriana Aguilar-Mahecha, Margarita Souleimanova, Sarkis Meterissian, Jamil Asselah, Nicholas Bertos, Constanza Martinez, Hellen Kuasne, Alain Pacis
Publikováno v:
Communications Biology
Communications Biology, Vol 3, Iss 1, Pp 1-15 (2020)
Communications Biology, Vol 3, Iss 1, Pp 1-15 (2020)
Subsets of breast tumors present major clinical challenges, including triple-negative, metastatic/recurrent disease and rare histologies. Here, we developed 37 patient-derived xenografts (PDX) from these difficult-to-treat cancers to interrogate thei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d182d92173c4f93c4e05351170ea7c17
https://doi.org/10.1038/s42003-020-1042-x
https://doi.org/10.1038/s42003-020-1042-x
Publikováno v:
Analytical Methods. 10:2854-2862
Pre-concentration and clean-up are essential sample preparation steps in environmental, forensics and bio-analytical assays. Here, we present work towards a fully integrated, replica molded all thiol–ene lab-on-a-chip solution for sample enrichment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77cd0b1115cb81ad5be53eb9b46411ea
https://doi.org/10.1039/c8ay00646f
https://doi.org/10.1039/c8ay00646f
Autor:
Rasmus R. Svejdal, Alexander Jönsson, Jörg Peter Kutter, Henrik Flindt, Josiane P. Lafleur, Nanna Bøgelund, Kasper D. Rand, Tam T. T. N. Nguyen
Publikováno v:
Analytical Chemistry. 89:4573-4580
To improve the sample handling, and reduce cost and preparation time, of peptide mapping LC-MS workflows in protein analytical research, we here investigate the possibility of replacing conventional enzymatic digestion methods with a polymer microflu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8f1ecc84a0e6aa46e5ed2f392e4d63e
https://doi.org/10.1021/acs.analchem.6b05103
https://doi.org/10.1021/acs.analchem.6b05103
Autor:
Adriana Aguilar-Mahecha, Yirui Gui, Urszula Krzemien, Josiane P. Lafleur, Abdel Hosein, Marguerite Buchanan, Michael Pollak, Cristiano Ferrario, Mark Basik
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 25(23)
Purpose: The microenvironment of metastatic breast cancer is incompletely characterized, despite prior evidence that it plays a key role in the biology of metastasis. A major component of the tumor stroma is the carcinoma-associated fibroblast (CAF),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a69034ace2b43e13b986c037732ec33
https://pubmed.ncbi.nlm.nih.gov/31515454
https://pubmed.ncbi.nlm.nih.gov/31515454
Autor:
Sheida Nabavi, Olga Aleynikova, Marie-Christine Guilbert, Josee-Anne Roy, Cristiano Ferrario, Ciara H. O'Flanagan, Stephen D. Hursting, Horace Uri Saragovi, Aparna Ramanathan, René P. Zahedi, Stéphanie Légaré, Cathy Lan, Sylvia Josephy, Luca Cavallone, Emma Fowler, Mark Basik, Elizabeth A. Marcus, Naciba Benlimame, Vincent R. Richard, Eric Bareke, Christoph H. Borchers, Marguerite Buchanan, Urszula Krzemien, Adriana Aguilar-Mahecha, Ewa Przybytkowski, Catalin Mihalcioiu, Viet Vu, Josiane P. Lafleur, Amine Saad, Banujan Balachandran, André Robidoux, Michelle Scriver, Moulay A. Alaoui-Jamali, Jacek Majewski, Peter J. Tonellato, Isabelle Sirois, Catherine Chabot
Publikováno v:
Molecular cancer research : MCR. 17(12)
The major obstacle in successfully treating triple-negative breast cancer (TNBC) is resistance to cytotoxic chemotherapy, the mainstay of treatment in this disease. Previous preclinical models of chemoresistance in TNBC have suffered from a lack of c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::895771a889acf97c1b59202fe29f8a47
https://pubmed.ncbi.nlm.nih.gov/31537618
https://pubmed.ncbi.nlm.nih.gov/31537618
Autor:
Josiane P. Lafleur, Graham McLennan, Nathan Faulkner, Susie Brousse, Olga Savichtcheva, Kimberly A. Holden, Taylor J. Jensen, Mark Basik, Adriana Aguilar-Mahecha
Publikováno v:
Cancers
Volume 13
Issue 6
Cancers, Vol 13, Iss 1331, p 1331 (2021)
Volume 13
Issue 6
Cancers, Vol 13, Iss 1331, p 1331 (2021)
Background: Circulating tumor DNA (ctDNA) offers high sensitivity and specificity in metastatic cancer. However, many ctDNA assays rely on specific mutations in recurrent genes or require the sequencing of tumor tissue, difficult to do in a metastati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9590bbdfdf5f66b9a2fb03a4abae1930
https://doi.org/10.3390/cancers13061331
https://doi.org/10.3390/cancers13061331
Autor:
Kell Mortensen, Jörg Peter Kutter, Mark Gontsarik, Anan Yaghmur, Josiane P. Lafleur, Aghiad Ghazal, Ana Labrador
Publikováno v:
Ghazal, A, Gontsarik, M, Kutter, J P, Lafleur, J P, Labrador, A, Mortensen, K & Yaghmur, A 2016, ' Direct monitoring of calcium-triggered phase transitions in cubosomes using small-angle X-ray scattering combined with microfluidics ', Journal of Applied Crystallography, vol. 49, no. 6, pp. 2005-2014 . https://doi.org/10.1107/S1600576716014199
This article introduces a simple microfluidic device that can be combined with synchrotron small-angle X-ray scattering (SAXS) for monitoring dynamic structural transitions. The microfluidic device is a thiol-ene-based system equipped with 125 μm-th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::396c45f4f485f3e958a2f23a1e7d4667
https://doi.org/10.1107/s1600576716014199
https://doi.org/10.1107/s1600576716014199
Autor:
Graham McLennan, Susie Brousse, Mark Basik, Adriana Aguilar-Mahecha, Josiane P. Lafleur, Cristiano Ferrario, Taylor J. Jensen, Kimberly A. Holden
Publikováno v:
Cancer Research. 80:1968-1968
Metastatic breast cancer is mostly incurable and patients are treated with serial chemotherapy regimens to prolong life and decrease symptoms. Treatment efficacy is usually monitored by imaging every 3 months and by the measurement of blood tumor bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4418fa5e3a3f461cf831b9183b912ef
https://doi.org/10.1158/1538-7445.am2020-1968
https://doi.org/10.1158/1538-7445.am2020-1968