Výsledky vyhledávání - "Josiane Demignon"

Akademický článek

Six homeoproteins directly activate Myod expression in the gene regulatory networks that control early myogenesis.

Autor: Frédéric Relaix, Josiane Demignon, Christine Laclef, Julien Pujol, Marc Santolini, Claire Niro, Mounia Lagha, Didier Rocancourt, Margaret Buckingham, Pascal Maire

Publikováno v: PLoS Genetics, Vol 9, Iss 4, p e1003425 (2013)

In mammals, several genetic pathways have been characterized that govern engagement of multipotent embryonic progenitors into the myogenic program through the control of the key myogenic regulatory gene Myod. Here we demonstrate the involvement of Si

Externí odkaz: https://doaj.org/article/e50a5896192a487d8eb7505fb51e7086

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SIX1 and SIX4 homeoproteins regulate PAX7+ progenitor cell properties during fetal epaxial myogenesis

Autor: Fabien Le Grand, Josiane Demignon, Stephen J. Tapscott, Athanassia Sotiropoulos, Pascal Maire, Elisa Negroni, Rouba Madani, Benjamin Saintpierre, Vincent Mouly, Carmen Birchmeier, Helge Amthor, Nathalie Chaverot, Maud Wurmser, Hiroshi Sakai, Shahragim Tajbakhsh

Publikováno v: Development (Cambridge, England)
Development (Cambridge, England), Company of Biologists, 2020, pp.dev.185975. ⟨10.1242/dev.185975⟩
Development (Cambridge, England), 2020, pp.dev.185975. ⟨10.1242/dev.185975⟩

International audience; Pax7 expression marks stem cells in developing skeletal muscles and adult satellite cells during homeostasis and muscle regeneration. The genetic determinants that control the entrance into the myogenic program and the appeara

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17bbf54927c7212a339135605256ac24
https://hal.sorbonne-universite.fr/hal-02905565

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Bone resorption by isolated chick osteoclasts in culture is stimulated by murine spleen cell supernatant fluids (Osteoclast-Activating Factor) and inhibited by calcitonin and prostaglandin E2

Autor: Lynn Neff, Marie-Christine de Vernejoul, Mark C. Horowitz, Roland Baron, Josiane Demignon

Publikováno v: Journal of Bone and Mineral Research. 3:69-80

The question of whether any of the agents known to activate bone resorption in vivo or in organ cultures acts directly on the osteoclast or via intermediate target cells that secondarily secrete locally paracrine factors is important for our understa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2146e3f56183ea5af933c643d0251002
https://doi.org/10.1002/jbmr.5650030111

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Six1 and Six4 homeoproteins are required for Pax3 and Mrf expression during myogenesis in the mouse embryo

Autor: Josiane Demignon, Mary J. Seller, Raphaëlle Grifone, Christophe Houbron, Claire Niro, Ghislaine Hamard, Pascal Maire, Evelyne Souil

Publikováno v: Development. 132:2235-2249

In mammals, Six5, Six4 and Six1 genes are co-expressed during mouse myogenesis. Six4 and Six5 single knockout (KO) mice have no developmental defects, while Six1 KO mice die at birth and show multiple organ developmental defects. We have generated Si

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ce25184e7f618d04e83e672be0dc1f9
https://doi.org/10.1242/dev.01773

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Thymus, kidney and craniofacial abnormalities in Six1 deficient mice

Autor: Josiane Demignon, Pascal Maire, Christine Laclef, Evelyne Souil

Publikováno v: Mechanisms of Development. 120(6):669-679

Six genes are widely expressed during vertebrate embryogenesis, suggesting that they are implicated in diverse differentiation processes. To determine the functions of the Six1 gene, we constructed Six1-deficient mice by replacing its first exon by t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::551925f5992b31f1c02ddca1da18ab24

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[Untitled]

Autor: Charles A. Thornton, Patrick Barbet, Pascal Maire, Kyoshi Kawakami, Josiane Demignon, Jacques S. Beckmann, Françoise Fougerousse, Hidenori Ozaki, Soledad Lopez, Laurence Suel, Muriel Durand

Publikováno v: Journal of Muscle Research and Cell Motility. 23:255-264

This report describes the characterisation of the expression profile of several myogenic determination genes during human embryogenesis. The data were obtained from axial structures and limb buds of human embryos aged between 3 and 8 weeks of develop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::31abc71308d1751a360e45ff777412eb
https://doi.org/10.1023/a:1020990825644

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Expression of myogenin during embryogenesis is controlled by Six/ sine oculis homeoproteins through a conserved MEF3 binding site

Autor: Josiane Demignon, Jean-Paul Concordet, Axel Kahn, Pascal Maire, Arlette Porteu, François Spitz, Dominique Daegelen

Publikováno v: Proceedings of the National Academy of Sciences. 95:14220-14225

Myogenin, one of the MyoD family of proteins, is expressed early during somitogenesis and is required for myoblast fusion in vivo . Previous studies in transgenic mice have shown that a 184-bp myogenin promoter fragment is sufficient to correctly dri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6545e419c684c33bf36680e49f4f1c37
https://doi.org/10.1073/pnas.95.24.14220

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A Combination of MEF3 and NFI Proteins Activates Transcription in a Subset of Fast-Twitch Muscles

Autor: Josiane Demignon, Axel Kahn, Dominique Daegelen, François Spitz, Pascal Maire, Marjo Salminen

Publikováno v: University of Helsinki

The human aldolase A pM promoter is active in fast-twitch muscles. To understand the role of the different transcription factors which bind to this promoter and determine which ones are responsible for its restricted pattern of expression, we analyze

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07947bd3cfb8a4693d742d0551bd0747
https://doi.org/10.1128/mcb.17.2.656

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Uterine cells other than stromal decidual cells are required for 1,25-dihydroxyvitamin D3production during early human pregnancy

Autor: Josiane Demignon, Michèle Garabédian, Evelyne Cynober, Moustapha Kachkache, Charlyne Rebut-Bonneton

Publikováno v: FEBS Letters. 333:83-88

Human decidual cells are known to produce 1,25-(OH)2D3 at the end of pregnancy, the present study evaluates this capacity, and the part played by stromal decidual cells, in early pregnancy. Cells were obtained from nine human decidua by aspiration or

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4ca02aa709d7d3d76a397e7d9fbd46d
https://doi.org/10.1016/0014-5793(93)80379-9

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Six1 and Six4 gene expression is necessary to activate the fast-type muscle gene program in the mouse primary myotome

Autor: Pascal Maire, Julien Giordani, Nicolas Sgarioto, Josiane Demignon, Maryline Favier, Yubing Liu, Stéphane D. Vincent, Alexandre Blais, Claire Niro, Isabelle Guillet-Deniau

Publikováno v: Developmental Biology
Developmental Biology, 2010, 338 (2), pp.168-182. ⟨10.1016/j.ydbio.2009.11.031⟩
Developmental Biology, Elsevier, 2010, 338 (2), pp.168-182. ⟨10.1016/j.ydbio.2009.11.031⟩

International audience; While the signaling pathways and transcription factors active in adult slow- and fast-type muscles begin to be characterized, genesis of muscle fiber-type diversity during mammalian development remains unexplained. We provide

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01cb4c86ce2c6db3097dfc1fe856a69b
https://hal.science/hal-02130299

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