Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Josiah K. Leong"'
Autor:
Josiah K. Leong, Tiffany C. Ho, Natalie L. Colich, Lucinda Sisk, Brian Knutson, Ian H. Gotlib
Publikováno v:
Developmental Cognitive Neuroscience, Vol 47, Iss , Pp 100881- (2021)
The motivation to approach or avoid incentives can change during adolescence. Advances in neuroimaging allow researchers to characterize specific brain circuits that underlie these developmental changes. Whereas activity in the nucleus accumbens (NAc
Externí odkaz:
https://doaj.org/article/dd807a40a37a4304a93f32e8e35c8768
Autor:
Luke W. Bonham, Ethan G. Geier, Daniel W. Sirkis, Josiah K. Leong, Eliana Marisa Ramos, Qing Wang, Anna Karydas, Suzee E. Lee, Virginia E. Sturm, Russell P. Sawyer, Adit Friedberg, Justin K. Ichida, Aaron D. Gitler, Leo Sugrue, Michael Cordingley, Walter Bee, Eckard Weber, Joel H. Kramer, Katherine P. Rankin, Howard J. Rosen, Adam L. Boxer, William W. Seeley, John Ravits, Bruce L. Miller, Jennifer S. Yokoyama
Publikováno v:
The Journal of Neuroscience. 43:333-345
Hexanucleotide repeat expansion (HRE) withinC9orf72is the most common genetic cause of frontotemporal dementia (FTD). Thalamic atrophy occurs in both sporadic and familial FTD but is thought to distinctly affect HRE carriers. Separately, emerging evi
Autor:
Luke W. Bonham, Ethan G. Geier, Daniel W. Sirkis, Josiah K. Leong, Eliana Marisa Ramos, Qing Wang, Anna Karydas, Suzee E. Lee, Virginia E. Sturm, Russell P. Sawyer, Adit Friedberg, Justin K. Ichida, Aaron D. Gitler, Leo Sugrue, Michael Cordingley, Walter Bee, Eckard Weber, Joel Kramer, Katherine P. Rankin, Howard J. Rosen, Adam L. Boxer, William W. Seeley, John Ravits, Bruce L. Miller, Jennifer S. Yokoyama
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 43, iss 2
Hexanucleotide repeat expansion (HRE) within C9orf72 is the most common genetic cause of frontotemporal dementia (FTD). Thalamic atrophy occurs in both sporadic and familial FTD but is thought to distinctly affect HRE carriers. Separately, emerging e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26db290663368430e8978af72589564d
https://escholarship.org/uc/item/7jr289cm
https://escholarship.org/uc/item/7jr289cm
Autor:
Luke W, Bonham, Ethan G, Geier, Daniel W, Sirkis, Josiah K, Leong, Eliana Marisa, Ramos, Qing, Wang, Anna, Karydas, Suzee E, Lee, Virginia E, Sturm, Russell P, Sawyer, Adit, Friedberg, Justin K, Ichida, Aaron D, Gitler, Leo, Sugrue, Michael, Cordingley, Walter, Bee, Eckard, Weber, Joel, Kramer, Katherine P, Rankin, Howard J, Rosen, Adam L, Boxer, William W, Seeley, John, Ravits, Bruce L, Miller, Jennifer S, Yokoyama
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience.
Hexanucleotide repeat expansion (HRE) within
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Diffusion tractography allows identification and measurement of structural tracts in the human brain previously associated with motivated behavior in animal models. Recent findings indicate that the structural properties of a tract connecting the mid
Publikováno v:
Cognitive, Affective & Behavioral Neuroscience
Older adults are disproportionately targeted by fraud schemes that advertise unlikely but large returns (positively skewed risks). We examined adult age differences in choice and neural activity as individuals considered risky gambles. Gambles were s
Autor:
Josiah K. Leong, Ian H. Gotlib, Natalie L. Colich, Lucy S. King, Tiffany C. Ho, Kathryn L. Humphreys, Sarah J. Ordaz
Publikováno v:
Social Cognitive and Affective Neuroscience
Previous research suggests that exposure to early life stress (ELS) affects the structural integrity of the uncinate fasciculus (UF), a frontolimbic white matter tract that undergoes protracted development throughout adolescence. Adolescence is an im
Autor:
Natalie L. Colich, Tiffany C. Ho, Josiah K. Leong, Brian Knutson, Lucinda M. Sisk, Ian H. Gotlib
Publikováno v:
Developmental Cognitive Neuroscience
Developmental Cognitive Neuroscience, Vol 47, Iss, Pp 100881-(2021)
Developmental Cognitive Neuroscience, Vol 47, Iss, Pp 100881-(2021)
Highlights • Characterized the anterior insula (AIns) to nucleus accumbens (NAcc) white-matter tract for the first time in adolescents. • Structural coherence of the AIns-NAcc tract correlated with less NAcc functional activity during anticipatio
Autor:
Josiah K. Leong, Chun Chieh Fan, Ole A. Andreassen, Rahul S. Desikan, Gerard D. Schellenberg, John Kornak, Anders M. Dale, Jennifer S. Yokoyama, Lilah M. Besser, Bruce L. Miller, Walter A. Kukull, Howard J. Rosen, William P. Dillon, Ethan G. Geier, Luke W. Bonham, Christopher P. Hess
Publikováno v:
Annals of Clinical and Translational Neurology
Objective The ε4 allele of apolipoprotein E (APOE) is the strongest known common genetic risk factor for Alzheimer's disease (AD) and alters age of onset in retrospective studies. Here, we longitudinally test the effects of APOE ε4 genotype and age
Publikováno v:
Neuron. 89(1):63-69
Individuals sometimes show inconsistent risk preferences, including excessive attraction to gambles featuring small chances of winning large amounts (called "positively skewed" gambles). While functional neuroimaging research indicates that nucleus a