Fluorescent Tools to Analyze Peroxisome–Endoplasmic Reticulum Interactions in Mammalian Cells

Autor: Alexa Bishop, Maki Kamoshita, Josiah B. Passmore, Christian Hacker, Tina A. Schrader, Hans R. Waterham, Joseph L. Costello, Michael Schrader

Publikováno v: Contact, Vol 2 (2019)

Peroxisomes (POs) and the endoplasmic reticulum (ER) cooperate extensively in lipid-related metabolic pathways, and the ER also provides phospholipids to enable the peroxisomal membrane to expand prior to division. Recently, we identified peroxisomal

Externí odkaz: https://doaj.org/article/9e6321b436de46c48b9495c1c172f1fc

Mitochondrial fission factor (MFF) is a critical regulator of peroxisome maturation

Autor: Luis F. Godinho, Celien Lismont, Ruth E. Carmichael, Marc Fransen, Peter Freisinger, Christian Hacker, Markus Islinger, Yunhong Wang, Michael Schrader, Sacha Ferdinandusse, Josiah B. Passmore, David M. Richards, Tina A. Schrader

Publikováno v: BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 1867(7):118709. Elsevier
Biochimica et Biophysica Acta. Molecular Cell Research

Peroxisomes are highly dynamic subcellular compartments with important functions in lipid and ROS metabolism. Impaired peroxisomal function can lead to severe metabolic disorders with developmental defects and neurological abnormalities. Recently, a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f71618f64ddde7c5bfa06a81ad78908a

Fluorescent tools to analyse peroxisome-ER interactions in mammalian cells

Autor: Alexa, Bishop, Maki, Kamoshita, Josiah B, Passmore, Christian, Hacker, Tina A, Schrader, Hans R, Waterham, Joseph L, Costello, Michael, Schrader

Publikováno v: Contact (Thousand Oaks (Ventura County, Calif.)). 2

Peroxisomes and the endoplasmic reticulum (ER) cooperate extensively in lipid-related metabolic pathways, and the ER also provides phospholipids to enable the peroxisomal membrane to expand prior to division. Recently, we identified peroxisomal prote

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fa8580f7459e0439519c7afaed214f27
https://pubmed.ncbi.nlm.nih.gov/31198905

Multi-localized Proteins: The Peroxisome-Mitochondria Connection

Autor: Joseph L, Costello, Josiah B, Passmore, Markus, Islinger, Michael, Schrader

Publikováno v: Sub-cellular biochemistry. 89

Peroxisomes and mitochondria are dynamic, multifunctional organelles that play pivotal cooperative roles in the metabolism of cellular lipids and reactive oxygen species. Their functional interplay, the "peroxisome-mitochondria connection", also incl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2dbfa8f938543b910420c2a54aefdf46
https://pubmed.ncbi.nlm.nih.gov/30378033

Co-regulation map of the human proteome enables identification of protein functions

Autor: Michael Schrader, Juri Rappsilber, Piotr Grabowski, Josiah B. Passmore, Georg Kustatscher, Tina A. Schrader

Publikováno v: Nat Biotechnol
Kustatscher, G, Grabowski, P, Schrader, T A, Passmore, J B, Schrader, M & Rappsilber, J 2019, ' Co-regulation map of the human proteome enables identification of protein functions ', Nature Biotechnology, vol. 37, no. 11, pp. 1361-1371 . https://doi.org/10.1038/s41587-019-0298-5

Assigning functions to the vast array of proteins present in eukaryotic cells remains challenging. To identify relationships between proteins, and thereby enable functional annotation of proteins, we determined changes in abundance of 10,323 human pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dacd1ffe03f5d86d1ce507274968f77e
https://pubmed.ncbi.nlm.nih.gov/31907475