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pro vyhledávání: '"Joshua Zent"'
Autor:
Joshua Zent, Lian-Wang Guo
Publikováno v:
Cellular Physiology and Biochemistry, Vol 49, Iss 3, Pp 848-868 (2018)
Myofibroblasts are central mediators of fibrosis. Typically derived from resident fibroblasts, myofibroblasts represent a heterogeneous population of cells that are principally defined by acquired contractile function and high synthetic ability to pr
Externí odkaz:
https://doaj.org/article/77ee9fb5a0b44e67b8ea413169f5d384
Autor:
Joshua Zent, Steven T. Sizemore, Joe T. Sharick, Caitlin E. Jones, Samir N. Ghadiali, Michael C. Ostrowski, Jennifer L. Leight, Sheila E. Colbert, Vasudha C. Shukla
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 2, p e0245653 (2021)
PLoS ONE, Vol 16, Iss 2, p e0245653 (2021)
Collagen deposition contributes to both high mammographic density and breast cancer progression. Low stromal PTEN expression has been observed in as many as half of breast tumors and is associated with increases in collagen deposition, however the me
Autor:
Sydney Blum, Seth Blackshaw, Andy J. Fischer, Joshua Zent, Jennifer L. Leight, Thanh Hoang, Warren A. Campbell, Jessica L Weist, Ameya Deshmukh, Ninoshka Mendonca, Levi Todd
Publikováno v:
Exp Neurol
Gelatinases are a class of matrix metalloproteinases (MMPs) that degrade the extracellular matrix (ECM) to regulate intercellular signaling and cell migration. Gelatinase activity is tightly regulated via proteolytic activation and through the expres
Autor:
Mirnal Chaudhary, Daniel Direnzo, Xu Dong Shi, Sarah Franco, Joshua Zent, Christopher Little, Katie Wang, Bo Liu, Lian-Wang Guo, K Craig Kent
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 35
Introduction: Endovascular interventions are the first line treatment for patients with atherosclerotic disease. However, a significant number of these fail due to neointimal hyperplasia. The Wnt4/β-catenin pathway has been reported to play an impor
Autor:
Joshua Zent, Alycia Kent, Toshio Takayama, Daniel DiRenzo, Yifan Zhou, Lian-Wang Guo, Sarah Franco, Bowen Wang, Peter Hartig, Xudong Shi
Cardiovascular disease caused by atherosclerosis is the leading cause of death in the developed world. Narrowing of the vessel lumen, due to atherosclerotic plaque development or the rupturing of established plaques, interrupts normal blood flow lead
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f9b1708fb79b515ba590a738464b1da
https://europepmc.org/articles/PMC4401250/
https://europepmc.org/articles/PMC4401250/
Publikováno v:
Cancer Research. 77:4782-4782
Cancer stem cells (CSCs) are a subpopulation of tumor cells that are uniquely capable of initiating and sustaining tumorigenesis, and they have also been implicated in driving disease recurrence after cancer therapy. We have previously developed a no