Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Joshua Z Johnson"'
Autor:
Jacob M Vogan, Xiaozhu Zhang, Daniel T Youmans, Samuel G Regalado, Joshua Z Johnson, Dirk Hockemeyer, Kathleen Collins
Publikováno v:
eLife, Vol 5 (2016)
We dissected the importance of human telomerase biogenesis and trafficking pathways for telomere maintenance. Biological stability of human telomerase RNA (hTR) relies on H/ACA proteins, but other eukaryotes use other RNP assembly pathways. To invest
Externí odkaz:
https://doaj.org/article/7193f9ced9e947cf8f83b9491ed498d1
Publikováno v:
eLife, Vol 4 (2015)
Mutations in the human telomerase reverse transcriptase (TERT) promoter are the most frequent non-coding mutations in cancer, but their molecular mechanism in tumorigenesis has not been established. We used genome editing of human pluripotent stem ce
Externí odkaz:
https://doaj.org/article/abbb8ecceb244b1b94b18a6e58c18a51
Autor:
Joshua Z Johnson, Dirk Hockemeyer, Kelsey M. Hennick, Brendan Finnerty, Mary L McMaster, Ryan Forster, Casey Drubin, Sarah B. Short, Won-Tae Kim, Seung-A Sara Choo
Publikováno v:
The EMBO Journal
Mutations in the shelterin protein POT1 are associated with chronic lymphocytic leukemia (CLL), Hodgkin lymphoma, angiosarcoma, melanoma, and other cancers. These cancer‐associated POT1 (caPOT1) mutations are generally heterozygous, missense, or no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dc0beae85ffabd033b66f635ee3e4af
http://europepmc.org/articles/PMC8204863
http://europepmc.org/articles/PMC8204863
Autor:
Joshua Z Johnson, Dirk Hockemeyer
Publikováno v:
Current Opinion in Cell Biology. 37:84-90
Human stem cell-based disease models have great promise to advance our understanding of human disease. These models can be derived from patients with genetic disorders and manipulated with genome editing and myriad differentiation protocols to model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45968146f70f83decf9e2fb04a4134e9
https://doi.org/10.1016/j.ceb.2015.10.007
https://doi.org/10.1016/j.ceb.2015.10.007
Autor:
Kathleen Collins, Joshua Z Johnson, Samuel G. Regalado, Jacob M. Vogan, Dirk Hockemeyer, Daniel T. Youmans, Xiaozhu Zhang
Publikováno v:
eLife, Vol 5 (2016)
Vogan, JM; Zhang, X; Youmans, DT; Regalado, SG; Johnson, JZ; Hockemeyer, D; et al.(2016). Minimized human telomerase maintains telomeres and resolves endogenous roles of H/ACA proteins, TCAB1, and Cajal bodies. eLife, 5(AUGUST). doi: 10.7554/eLife.18221. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/67v7829g
eLife, vol 5, iss AUGUST
eLife
Vogan, JM; Zhang, X; Youmans, DT; Regalado, SG; Johnson, JZ; Hockemeyer, D; et al.(2016). Minimized human telomerase maintains telomeres and resolves endogenous roles of H/ACA proteins, TCAB1, and Cajal bodies. eLife, 5(AUGUST). doi: 10.7554/eLife.18221. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/67v7829g
eLife, vol 5, iss AUGUST
eLife
We dissected the importance of human telomerase biogenesis and trafficking pathways for telomere maintenance. Biological stability of human telomerase RNA (hTR) relies on H/ACA proteins, but other eukaryotes use other RNP assembly pathways. To invest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2d13f4e7363c49ef885858c62261bb5
https://elifesciences.org/articles/18221
https://elifesciences.org/articles/18221
Autor:
Dirk Hockemeyer, Joshua Z Johnson, John M. Boyle, Tina Wagner, Jacob M. Vogan, Kunitoshi Chiba
Publikováno v:
eLife, Vol 4 (2015)
eLife, vol 4, iss JULY 2015
eLife, vol 4, iss JULY 2015
The bulk of the DNA in the human genome is divided between 23 pairs of chromosomes. The ends of these chromosomes contain a repetitive stretch of DNA known as a telomere. Every time a cell divides, a portion of the telomere is lost and can be restore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee727a0669822659e45dd22458638f1c
https://doi.org/10.7554/elife.07918
https://doi.org/10.7554/elife.07918
Autor:
Vogan, Jacob M., Xiaozhu Zhang, Youmans, Daniel T., Regalado, Samuel G., Johnson, Joshua Z., Hockemeyer, Dirk, Collins, Kathleen
Publikováno v:
eLife; 2016, p1-21, 21p