Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Joshua X. Wang"'
Autor:
Masaru Sasaki, Takeo Hara, Joshua X. Wang, Yusen Zhou, Kanak V. Kennedy, Chizoba N. Umeweni, Maiya A. Alston, Zachary C. Spergel, Satoshi Ishikawa, Ryugo Teranishi, Ritsu Nakagawa, Emily A. Mcmillan, Kelly A. Whelan, Tatiana A. Karakasheva, Kathryn E. Hamilton, Melanie A. Ruffner, Amanda B. Muir
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 17, Iss 6, Pp 923-937 (2024)
Background & Aims: Epithelial disruption in eosinophilic esophagitis (EoE) encompasses both impaired differentiation and diminished barrier integrity. We have shown that lysyl oxidase (LOX), a collagen cross-linking enzyme, is up-regulated in the eso
Externí odkaz:
https://doaj.org/article/4642d52f7d81435797854e2d8c616673
Autor:
Meenhard Herlyn, Ze'ev A. Ronai, Keith T. Flaherty, David W. Speicher, Joseph M. Salvino, Genevieve M. Boland, Dennie T. Frederick, Lawrence N. Kwong, Ravi K. Amaravadi, Tara C. Mitchell, Lynn M. Schuchter, Xiaowei Xu, Giorgos C. Karakousis, Wei Xu, Gordon B. Mills, Yiling Lu, Lawrence W. Wu, Denitsa M. Hristova, Adina Vultur, Rajasekharan Somasundaram, Marilda Beqiri, Joshua X. Wang, Patricia Brafford, Katrin Sproesser, Alice S. Morias, Maya Delvadia, Ye Huang, Cynthia Tong, Bela Delvadia, Chih-Cheng Yang, Pedro Aza-Blanc, Clemens Krepler, Mizuho Fukunaga-Kalabis, Gretchen M. Alicea, Zhi Wei, Chaoran Cheng, Jie Zhang, Delaine Zayasbazan, Anastasia Samarkina, Gao Zhang, Ling Li, Min Xiao, Alexis Gutierrez, Qin Liu, Thomas Connelly, Andrew V. Kossenkov, Vito W. Rebecca, Jianglan Liu
Supplementary Table
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f597d79e512bde4e97ec399e76a72a4
https://doi.org/10.1158/0008-5472.22490530.v1
https://doi.org/10.1158/0008-5472.22490530.v1
Autor:
Meenhard Herlyn, Ze'ev A. Ronai, Keith T. Flaherty, David W. Speicher, Joseph M. Salvino, Genevieve M. Boland, Dennie T. Frederick, Lawrence N. Kwong, Ravi K. Amaravadi, Tara C. Mitchell, Lynn M. Schuchter, Xiaowei Xu, Giorgos C. Karakousis, Wei Xu, Gordon B. Mills, Yiling Lu, Lawrence W. Wu, Denitsa M. Hristova, Adina Vultur, Rajasekharan Somasundaram, Marilda Beqiri, Joshua X. Wang, Patricia Brafford, Katrin Sproesser, Alice S. Morias, Maya Delvadia, Ye Huang, Cynthia Tong, Bela Delvadia, Chih-Cheng Yang, Pedro Aza-Blanc, Clemens Krepler, Mizuho Fukunaga-Kalabis, Gretchen M. Alicea, Zhi Wei, Chaoran Cheng, Jie Zhang, Delaine Zayasbazan, Anastasia Samarkina, Gao Zhang, Ling Li, Min Xiao, Alexis Gutierrez, Qin Liu, Thomas Connelly, Andrew V. Kossenkov, Vito W. Rebecca, Jianglan Liu
Metastatic melanoma is challenging to clinically address. Although standard-of-care targeted therapy has high response rates in patients with BRAF-mutant melanoma, therapy relapse occurs in most cases. Intrinsically resistant melanoma cells drive the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7d50cf4237143ffa8b8b8489bcade99
https://doi.org/10.1158/0008-5472.c.6533173
https://doi.org/10.1158/0008-5472.c.6533173
Autor:
Meenhard Herlyn, Ze'ev A. Ronai, Keith T. Flaherty, David W. Speicher, Joseph M. Salvino, Genevieve M. Boland, Dennie T. Frederick, Lawrence N. Kwong, Ravi K. Amaravadi, Tara C. Mitchell, Lynn M. Schuchter, Xiaowei Xu, Giorgos C. Karakousis, Wei Xu, Gordon B. Mills, Yiling Lu, Lawrence W. Wu, Denitsa M. Hristova, Adina Vultur, Rajasekharan Somasundaram, Marilda Beqiri, Joshua X. Wang, Patricia Brafford, Katrin Sproesser, Alice S. Morias, Maya Delvadia, Ye Huang, Cynthia Tong, Bela Delvadia, Chih-Cheng Yang, Pedro Aza-Blanc, Clemens Krepler, Mizuho Fukunaga-Kalabis, Gretchen M. Alicea, Zhi Wei, Chaoran Cheng, Jie Zhang, Delaine Zayasbazan, Anastasia Samarkina, Gao Zhang, Ling Li, Min Xiao, Alexis Gutierrez, Qin Liu, Thomas Connelly, Andrew V. Kossenkov, Vito W. Rebecca, Jianglan Liu
Supplementary Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::350dbd6729cb12cdd1ea63efc5cf162c
https://doi.org/10.1158/0008-5472.22490539
https://doi.org/10.1158/0008-5472.22490539
Autor:
Gao Zhang, Anastasia Samarkina, David W. Speicher, Vito W. Rebecca, Yiling Lu, Delaine Zayasbazan, Katrin Sproesser, Chih-Cheng Yang, Gordon B. Mills, Andrew V. Kossenkov, Mizuho Fukunaga-Kalabis, Pedro Aza-Blanc, Clemens Krepler, Qin Liu, Ravi K. Amaravadi, Dennie T. Frederick, Genevieve M. Boland, Denitsa Hristova, Jianglan Liu, Bela Delvadia, Jie Zhang, Patricia Brafford, Min Xiao, Keith T. Flaherty, Giorgos C. Karakousis, Ling Li, Lawrence N. Kwong, Marilda Beqiri, Gretchen M. Alicea, Tara C. Mitchell, Alice S. Morias, Alexis Gutierrez, Rajasekharan Somasundaram, Joseph M. Salvino, Thomas Connelly, Xiaowei Xu, Ye Huang, Ze'ev Ronai, Meenhard Herlyn, Cynthia Tong, Wei Xu, Chaoran Cheng, Zhi Wei, Joshua X. Wang, Lawrence W. Wu, Adina Vultur, Lynn M. Schuchter, Maya Delvadia
Publikováno v:
Cancer Res
Metastatic melanoma is challenging to clinically address. Although standard-of-care targeted therapy has high response rates in patients with BRAF-mutant melanoma, therapy relapse occurs in most cases. Intrinsically resistant melanoma cells drive the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a2fb29d7eacecedc0fae7182957f304
https://europepmc.org/articles/PMC8530965/
https://europepmc.org/articles/PMC8530965/
Autor:
Kathleen E. Sullivan, Kelly Maurer, Li Song, Jonathan M. Spergel, Melanie A. Ruffner, Joshua X. Wang, Amanda B. Muir, Margaret Carroll, Lihua Shi
Publikováno v:
Allergy
Background Germline-encoded innate immune pattern recognition receptors (PRR) are expressed at epithelial surfaces and modulate epithelial defenses. Evidence suggests that stimulation of the Toll-like receptor (TLR) family of PRR may regulate epithel
Autor:
Johannes Beckers, Marilda Beqiri, Richard A. Sturm, Joshua X. Wang, Robert Besch, Carola Berking, Frank J. Rauscher, Samir Zaman, Meenhard Herlyn, Jie Zhang, Mizuho Fukunaga-Kalabis, Denitsa Hristova, Markus V. Heppt, Brianna Evans, Martin Irmler, David E. Fisher, Ling Li, Zhi Wei
Publikováno v:
J. Invest. Dermatol. 138, 141-149 (2018)
Melanoma cells share many biological properties with neural crest stem cells. Here we show that the homeodomain transcription factor Msh homeobox 1 (MSX1), which is significantly correlated with melanoma disease progression, reprograms melanocytes an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a849b6378a6f255e6b5422d4898366a8
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=51946
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=51946
Autor:
Masahiro Oka, Mizuho Fukunaga-Kalabis, Alexandra V. Gyurdieva, Denitsa Hristova, Zhi Wei, Joshua X. Wang, Marie R. Webster, Ashani T. Weeraratna, Ling Li, Markus V. Heppt, Meenhard Herlyn
Publikováno v:
The Journal of investigative dermatology
Multipotent stem cells with neural crest–like properties have been identified in the dermis of human skin. These neural crest stem cell (NCSC)–like cells display self-renewal capacity and differentiate into neural crest derivatives, including epi
Autor:
Stephan N. Wagner, Margarita Maurer, André C. Müller, Joshua X. Wang, Frederick Keeney, Denitsa Hristova, Katja Parapatics, Meenhard Herlyn, J K Jensen, Sydney M. Shaffer, Rajasekharan Somasundaram, Ling Li, Arjun Raj, Keiryn L. Bennett, S Shin, Xiaowei Xu, Shujing Liu, Michela Perego
Publikováno v:
Oncogene
Perego, M, Maurer, M, Wang, J X, Shaffer, S, Müller, A C, Parapatics, K, Li, L, Hristova, D, Shin, S, Keeney, F, Liu, S, Xu, X, Raj, A, Jensen, J K, Bennett, K L, Wagner, S N, Somasundaram, R & Herlyn, M 2018, ' A slow-cycling subpopulation of melanoma cells with highly invasive properties ', Oncogene, vol. 37, pp. 302-312 . https://doi.org/10.1038/onc.2017.341
Perego, M, Maurer, M, Wang, J X, Shaffer, S, Müller, A C, Parapatics, K, Li, L, Hristova, D, Shin, S, Keeney, F, Liu, S, Xu, X, Raj, A, Jensen, J K, Bennett, K L, Wagner, S N, Somasundaram, R & Herlyn, M 2018, ' A slow-cycling subpopulation of melanoma cells with highly invasive properties ', Oncogene, vol. 37, pp. 302-312 . https://doi.org/10.1038/onc.2017.341
Melanoma is a heterogeneous tumor with different subpopulations showing different proliferation rates. Slow-cycling cells were previously identified in melanoma, but not fully biologically characterized. Using the label-retention method, we identifie
Publikováno v:
Journal of cell communication and signaling. 10(3)
In the vertebrate embryo, melanocytes arise from the neural crest, migrate to and colonize the basal layer within the skin and skin appendages. Post-migratory melanocytes are securely attached to the basement membrane, and their morphology, growth, a