Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Joshua X. D. Ang"'
Autor:
Michelle A. E. Anderson, Estela Gonzalez, Matthew P. Edgington, Joshua X. D. Ang, Deepak-Kumar Purusothaman, Lewis Shackleford, Katherine Nevard, Sebald A. N. Verkuijl, Timothy Harvey-Samuel, Philip T. Leftwich, Kevin Esvelt, Luke Alphey
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Aedes aegypti is the main vector of several major pathogens including dengue, Zika and chikungunya viruses. Classical mosquito control strategies utilizing insecticides are threatened by rising resistance. This has stimulated interest in new
Externí odkaz:
https://doaj.org/article/614c159f168f4a098969285fcd6be9c7
Autor:
Michelle A. E. Anderson, Estela Gonzalez, Joshua X. D. Ang, Lewis Shackleford, Katherine Nevard, Sebald A. N. Verkuijl, Matthew P. Edgington, Tim Harvey-Samuel, Luke Alphey
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-9 (2023)
CRISPR/Cas9-based homing gene drives have emerged as a potential new approach to mosquito control. Here the authors use transgenic lines with germline-specific regulatory elements to express Cas9 and achieve up to 94% inheritance bias, closing the ga
Externí odkaz:
https://doaj.org/article/64ff3dc761bd47ec983ffd6d6793279c
Autor:
Sebald A. N. Verkuijl, Estela Gonzalez, Ming Li, Joshua X. D. Ang, Nikolay P. Kandul, Michelle A. E. Anderson, Omar S. Akbari, Michael B. Bonsall, Luke Alphey
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
CRISPR/Cas gene drives can bias transgene inheritance through different mechanisms. Here the authors use gene linkage to show that in males inheritance bias of wGDe did not occur by homing, rather through increased propagation of the donor drive elem
Externí odkaz:
https://doaj.org/article/1a66b64f96604774b186ba32c58f94a4
Autor:
Sebald A. N. Verkuijl, Joshua X. D. Ang, Luke Alphey, Michael B. Bonsall, Michelle A. E. Anderson
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Making discrete and precise genetic changes to wild populations has been proposed as a means of addressing some of the world’s most pressing ecological and public health challenges caused by insect pests. Technologies that would allow this, such as
Externí odkaz:
https://doaj.org/article/8feba7854d1f42a891e515ee028d526f
Autor:
Joshua X. D. Ang, Khamisah A. Kadir, Dayang S. A. Mohamad, Asmad Matusop, Paul C. S. Divis, Khatijah Yaman, Balbir Singh
Publikováno v:
Parasites & Vectors, Vol 13, Iss 1, Pp 1-13 (2020)
Abstract Background Plasmodium knowlesi is a significant cause of human malaria in Sarawak, Malaysian Borneo. Only one study has been previously undertaken in Sarawak to identify vectors of P. knowlesi, where Anopheles latens was incriminated as the
Externí odkaz:
https://doaj.org/article/b57a9c53b1f54538818101ab721c70ca
Autor:
Michelle A.E. Anderson, Estela Gonzalez, Matthew P. Edgington, Joshua X. D. Ang, Deepak-Kumar Purusothaman, Lewis Shackleford, Katherine Nevard, Sebald A. N. Verkuijl, Tim Harvey-Samuel, Philip T. Leftwich, Kevin Esvelt, Luke Alphey
Aedes aegypti, the yellow fever mosquito, is the main vector of several major pathogens including yellow fever, dengue, Zika and chikungunya viruses. Classical mosquito control strategies, mainly utilizing insecticides, have had success in controllin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5141130b5cf9df58fc9dbe57a1369ab8
https://doi.org/10.1101/2022.08.12.503466
https://doi.org/10.1101/2022.08.12.503466
Autor:
Sebald A. N. Verkuijl, Estela Gonzalez, Ming Li, Joshua X. D. Ang, Nikolay P. Kandul, Michelle A. E. Anderson, Omar S. Akbari, Michael B. Bonsall, Luke Alphey
Publikováno v:
Nature communications, vol 13, iss 1
CRISPR/Cas gene drives can bias transgene inheritance through different mechanisms. Homing drives are designed to replace a wild-type allele with a copy of a drive element on the homologous chromosome. In Aedes aegypti, the sex-determining locus is c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e178d7eb1ba9c7be5f7d67d95545403
https://pubmed.ncbi.nlm.nih.gov/36414618
https://pubmed.ncbi.nlm.nih.gov/36414618