Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Joshua W Osbun"'
Autor:
Mohamed Shehabeldin, Brendan Eby, Adam N Wallace, Amber Salter, Arindam R Chatterjee, Joshua W Osbun, Christopher J Moran, DeWitte T Cross, Akash P Kansagra
Publikováno v:
Stroke: Vascular and Interventional Neurology, Vol 1, Iss S1 (2021)
Introduction: Intravenous thrombolysis (IVT) and endovascular thrombectomy (EVT) are both standard of care treatments for acute ischemic stroke patients with large vessel occlusion (LVO) who are eligible for one or both treatments. IVT may result in
Externí odkaz:
https://doaj.org/article/8ae38e807cc2421794b816cb05647282
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 13 (2024)
Background Cervical arterial tortuosity is associated with adverse outcomes in Loeys‐Dietz syndrome and other heritable aortopathies. Methods and Results A method to assess tortuosity based on curvature of the vessel centerline in 3‐dimensional s
Externí odkaz:
https://doaj.org/article/81f1f393851444b8870a8859b4bfbc75
Autor:
Thomas F. Barrett, Bhuvic Patel, Saad M. Khan, Riley D. Z. Mullins, Aldrin K. Y. Yim, Sangami Pugazenthi, Tatenda Mahlokozera, Gregory J. Zipfel, Jacques A. Herzog, Michael R. Chicoine, Cameron C. Wick, Nedim Durakovic, Joshua W. Osbun, Matthew Shew, Alex D. Sweeney, Akash J. Patel, Craig A. Buchman, Allegra A. Petti, Sidharth V. Puram, Albert H. Kim
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Vestibular schwannomas (VS) are benign tumors that lead to significant neurologic and otologic morbidity. How VS heterogeneity and the tumor microenvironment (TME) contribute to VS pathogenesis remains poorly understood. In this study, we pe
Externí odkaz:
https://doaj.org/article/04db7437a9cc4724883e4e3f2bf21c43
Autor:
Anthony Z. Wang, Jay A. Bowman-Kirigin, Rupen Desai, Liang-I Kang, Pujan R. Patel, Bhuvic Patel, Saad M. Khan, Diane Bender, M. Caleb Marlin, Jingxian Liu, Joshua W. Osbun, Eric C. Leuthardt, Michael R. Chicoine, Ralph G. Dacey, Gregory J. Zipfel, Albert H. Kim, David G. DeNardo, Allegra A. Petti, Gavin P. Dunn
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-25 (2022)
Abstract Background Recent investigations of the meninges have highlighted the importance of the dura layer in central nervous system immune surveillance beyond a purely structural role. However, our understanding of the meninges largely stems from t
Externí odkaz:
https://doaj.org/article/c17233161de54fbe91f8411660beec7a
Autor:
David C. Lauzier, Keshav Jayaraman, Jane Y. Yuan, Deepti Diwan, Ananth K. Vellimana, Joshua W. Osbun, Arindam R. Chatterjee, Umeshkumar Athiraman, Rajat Dhar, Gregory J. Zipfel
Publikováno v:
Stroke. 54:1426-1440
Aneurysmal subarachnoid hemorrhage is a devastating condition causing significant morbidity and mortality. While outcomes from subarachnoid hemorrhage have improved in recent years, there continues to be significant interest in identifying therapeuti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::686d1638d5f79df242712c2eca75ac55
https://doi.org/10.1161/strokeaha.122.040072
https://doi.org/10.1161/strokeaha.122.040072
Publikováno v:
Neurosurgery Clinics of North America. 34:175-183
Mounting evidence has suggested a relationship between Chiari I malformation and idiopathic intracranial hypertension, with some studies implicating anomalies of the cerebral venous system in the development of these conditions. However, precise mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::489bc3a99761a8b5ed91db6c8ca9ae84
https://doi.org/10.1016/j.nec.2022.09.008
https://doi.org/10.1016/j.nec.2022.09.008
Autor:
Jay A. Bowman-Kirigin, Rupen Desai, Brian T. Saunders, Anthony Z. Wang, Maximilian O. Schaettler, Connor J. Liu, Alexandra J. Livingstone, Dale K. Kobayashi, Vivek Durai, Nicole M. Kretzer, Gregory J. Zipfel, Eric C. Leuthardt, Joshua W. Osbun, Michael R. Chicoine, Albert H. Kim, Kenneth M. Murphy, Tanner M. Johanns, Bernd H. Zinselmeyer, Gavin P. Dunn
Publikováno v:
Cancer Immunology Research. 11:20-37
The central nervous system (CNS) antigen-presenting cell (APC) that primes antitumor CD8+ T-cell responses remains undefined. Elsewhere in the body, the conventional dendritic cell 1 (cDC1) performs this role. However, steady-state brain parenchyma c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b58cb33b1a59b76b274c7a4bec8ecf1
https://doi.org/10.1158/2326-6066.cir-22-0098
https://doi.org/10.1158/2326-6066.cir-22-0098
Autor:
Samuel J. Cler, David C. Lauzier, Arindam R. Chatterjee, Joshua W. Osbun, Christopher J. Moran, Akash P. Kansagra
Publikováno v:
World Neurosurgery. 166:e750-e757
Rates of aneurysm occlusion following treatment with flow-diverting stents have been quantified at predefined time points in clinical trials, but data characterizing the continuous temporal progression of aneurysm occlusion are lacking. This study us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ab420c440d905026ce6b8bd096b6a22
https://doi.org/10.1016/j.wneu.2022.07.084
https://doi.org/10.1016/j.wneu.2022.07.084
Autor:
Gavin P. Dunn, Bernd H. Zinselmeyer, Tanner M. Johanns, Kenneth M. Murphy, Albert H. Kim, Michael R. Chicoine, Joshua W. Osbun, Eric C. Leuthardt, Gregory J. Zipfel, Nicole M. Kretzer, Vivek Durai, Dale K. Kobayashi, Alexandra J. Livingstone, Connor J. Liu, Maximilian O. Schaettler, Anthony Z. Wang, Brian T. Saunders, Rupen Desai, Jay A. Bowman-Kirigin
Supplementary Figures and Tables.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19ee81d152485914d2570e049914be76
https://doi.org/10.1158/2326-6066.22546134.v1
https://doi.org/10.1158/2326-6066.22546134.v1
Autor:
Gavin P. Dunn, Bernd H. Zinselmeyer, Tanner M. Johanns, Kenneth M. Murphy, Albert H. Kim, Michael R. Chicoine, Joshua W. Osbun, Eric C. Leuthardt, Gregory J. Zipfel, Nicole M. Kretzer, Vivek Durai, Dale K. Kobayashi, Alexandra J. Livingstone, Connor J. Liu, Maximilian O. Schaettler, Anthony Z. Wang, Brian T. Saunders, Rupen Desai, Jay A. Bowman-Kirigin
The central nervous system (CNS) antigen-presenting cell (APC) that primes antitumor CD8+ T-cell responses remains undefined. Elsewhere in the body, the conventional dendritic cell 1 (cDC1) performs this role. However, steady-state brain parenchyma c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cb45f311006488389e8bbe0e0d51222
https://doi.org/10.1158/2326-6066.c.6551106
https://doi.org/10.1158/2326-6066.c.6551106