Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Joshua T. Weinreb"'
Publikováno v:
Haematologica, Vol 107, Iss 3 (2021)
DEAD-box Helicase 41 (DDX41) is a recently identified factor mutated in hematologic malignancies whose function in hematopoiesis is unknown. Using an in vivo model of Ddx41 deficiency, we unveiled a critical role for this helicase in regulating eryth
Externí odkaz:
https://doaj.org/article/4cd34de674f44805b99fb798f4d8b85a
Autor:
Joshua T. Weinreb, Teresa V. Bowman
Publikováno v:
FEBS letters. 596(21)
DEAD-box Helicase 41 (DDX41) is a member of the DExD/H-box helicase family that has a variety of cellular functions. Of note, germline and somatic mutations in the DDX41 gene are prevalently found in myeloid malignancies. Here, we present a comprehen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1107f44976cc11be90e897dac67fdc8
https://pubmed.ncbi.nlm.nih.gov/36036093
https://pubmed.ncbi.nlm.nih.gov/36036093
Publikováno v:
Haematologica. 107(3)
DEAD-box Helicase 41 (DDX41) is a recently identified factor mutated in hematologic malignancies whose function in hematopoiesis is unknown. Using an in vivo model of Ddx41 deficiency, we unveiled a critical role for this helicase in regulating eryth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12941fce5a0f55eb28be66c148ad989f
https://pubmed.ncbi.nlm.nih.gov/33763998
https://pubmed.ncbi.nlm.nih.gov/33763998
Publikováno v:
Experimental Hematology. 88:S31-S32
Aberrant expansion of hematopoietic stem and progenitor cells (HSPCs) is a major hallmark of myelodysplastic syndromes (MDS), although the underlying molecular regulation remains poorly understood. DEAD-box Helicase 41 (DDX41) is an understudied MDS-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ec7dfd6b63774962ee7bb8edee80378
https://doi.org/10.1016/j.exphem.2020.09.174
https://doi.org/10.1016/j.exphem.2020.09.174
Autor:
Richard A. Padgett, Brad Tricomi, Noura Ghazale, Joshua T. Weinreb, Teresa V. Bowman, Noah J. Daniels, Amit Verma, Sofia de Oliveira, Kathryn S. Potts, Kith Pradhan, Varun Gupta
Publikováno v:
Developmental cell. 56(5)
Hematopoietic stem and progenitor cells (HSPCs) arise during embryonic development and are essential for sustaining the blood and immune systems throughout life. Tight regulation of HSPC numbers is critical for hematopoietic homeostasis. Here, we ide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8cdf1c859a62f45efd260ef49b64748
https://pubmed.ncbi.nlm.nih.gov/33689767
https://pubmed.ncbi.nlm.nih.gov/33689767
Publikováno v:
Blood. 134:772-772
Mutations in DEAD-box Helicase 41 (DDX41) are observed in patients with myelodysplastic syndromes (MDS) with inferior overall survival, implicating this factor in disease pathogenesis. DDX41 is an understudied factor with links to inflammation and RN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4543ccdc5503feff7a0b16b97efde828
https://doi.org/10.1182/blood-2019-124888
https://doi.org/10.1182/blood-2019-124888
Publikováno v:
Thyroid : official journal of the American Thyroid Association. 21(12)
Patients who undergo thyroidectomy often complain of weight gain, which they frequently attribute to inadequate thyroid hormone replacement. To assess the weight changes associated with thyroid hormone replacement or suppressive therapy after thyroid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0349d892e0ac6c0ab44e3b8393aa164
https://pubmed.ncbi.nlm.nih.gov/22066475
https://pubmed.ncbi.nlm.nih.gov/22066475