Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Joshua T. Kufera"'
Autor:
Jennifer A White, Joshua T Kufera, Niklas Bachmann, Weiwei Dai, Francesco R Simonetti, Ciara Armstrong, Jun Lai, Subul Beg, Janet D Siliciano, Robert F Siliciano
Publikováno v:
PLoS Pathogens, Vol 18, Iss 9, p e1010845 (2022)
Antiretroviral therapy (ART) effectively inhibits HIV-1 replication but is not curative due to the persistence of a latent viral reservoir in resting CD4+ T cells. This reservoir is a major barrier to cure. Sequencing studies have revealed that the p
Externí odkaz:
https://doaj.org/article/90c900152949401b8709754fb7fb5878
Autor:
Alexandra M. Bender, Janet D. Siliciano, Kyungyoon J. Kwon, Katherine M. Bruner, Hao Zhang, Christopher L. Nobles, Joshua T. Kufera, Gregory M. Laird, Steven G. Deeks, Ya Chi Ho, Annukka A.R. Antar, Lynn N. Bertagnolli, Frederic D. Bushman, Nikolas Wada, John R. Gregg, Srona Sengupta, Joseph B. Margolick, Subul A. Beg, Andrew E. Timmons, Adam A. Capoferri, Emily J. Fray, Katharine M. Jenike, Zheng Wang, Francesco R. Simonetti, Joel N. Blankson, Robert F. Siliciano
Publikováno v:
Nature
A stable latent reservoir for HIV-1 in resting CD4+ T cells is the principal barrier to a cure1-3. Curative strategies that target the reservoir are being tested4,5 and require accurate, scalable reservoir assays. The reservoir was defined with quant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20332f9fe8377a2db455ba3f4f29d45c
https://doi.org/10.1038/s41586-019-0898-8
https://doi.org/10.1038/s41586-019-0898-8