Zobrazeno 1 - 5
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pro vyhledávání: '"Joshua T. Arriola"'
Autor:
Huacan Lin, Eddy I. Jiménez, Joshua T. Arriola, Ulrich F. Müller, Ramanarayanan Krishnamurthy
Publikováno v:
Angewandte Chemie. 134
Publikováno v:
Angewandte Chemie International Edition. 61
Polymerization of nucleic acids in biology utilizes 5'-nucleoside triphosphates (NTPs) as substrates. The prebiotic availability of NTPs has been unresolved and other derivatives of nucleoside-monophosphates (NMPs) have been studied. However, this la
Publikováno v:
Science Advances
Description
An RNA that catalyzes the formation of GTP was developed with an emulsion-based in vitro selection system.
Synthesis of RNA in early life forms required chemically activated nucleotides, perhaps in the same form of nucleoside 5
An RNA that catalyzes the formation of GTP was developed with an emulsion-based in vitro selection system.
Synthesis of RNA in early life forms required chemically activated nucleotides, perhaps in the same form of nucleoside 5
Publikováno v:
Goldschmidt2021 abstracts.
Autor:
Ulrich Müller, Joshua T Arriola
Publikováno v:
Nucleic Acids Research
In vitro selections are the only known methods to generate catalytic RNAs (ribozymes) that do not exist in nature. Such new ribozymes are used as biochemical tools, or to address questions on early stages of life. In both cases, it is helpful to iden