Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Joshua T Herbeck"'
Autor:
Susan E Buskin, Richard J Lechtenberg, Francis A Slaughter, Joshua T Herbeck, Roxanne P Kerani, Matthew R Golden, Julia C Dombrowski
Publikováno v:
PLoS ONE, Vol 17, Iss 8, p e0272958 (2022)
BackgroundThe risk of HIV pre-exposure prophylaxis (PrEP) failure with sufficient medication adherence is extremely low but has occurred due to transmission of a viral strain with mutations conferring resistance to PrEP components tenofovir (TDF) and
Externí odkaz:
https://doaj.org/article/bc161612e9d54982a80afe7e1484eeef
Autor:
John E Mittler, James T Murphy, Sarah E Stansfield, Kathryn Peebles, Geoffrey S Gottlieb, Neil F Abernethy, Molly C Reid, Steven M Goodreau, Joshua T Herbeck
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 12, p e1007561 (2019)
Predominantly heterosexual HIV-1 epidemics like those in sub-Saharan Africa continue to have high HIV incidence in young people. We used a stochastic, agent-based model for age-disparate networks to test the hypothesis that focusing uptake and retent
Externí odkaz:
https://doaj.org/article/58b2431962a7409780a3a8aaf325492f
Publikováno v:
PLoS Computational Biology, Vol 10, Iss 6, p e1003673 (2014)
Trends in HIV virulence have been monitored since the start of the AIDS pandemic, as studying HIV virulence informs our understanding of HIV epidemiology and pathogenesis. Here, we model changes in HIV virulence as a strictly evolutionary process, us
Externí odkaz:
https://doaj.org/article/2abbf40792df41c49c309b2576e83bd3
Autor:
Paul J McLaren, Cédric Coulonges, Stephan Ripke, Leonard van den Berg, Susan Buchbinder, Mary Carrington, Andrea Cossarizza, Judith Dalmau, Steven G Deeks, Olivier Delaneau, Andrea De Luca, James J Goedert, David Haas, Joshua T Herbeck, Sekar Kathiresan, Gregory D Kirk, Olivier Lambotte, Ma Luo, Simon Mallal, Daniëlle van Manen, Javier Martinez-Picado, Laurence Meyer, José M Miro, James I Mullins, Niels Obel, Stephen J O'Brien, Florencia Pereyra, Francis A Plummer, Guido Poli, Ying Qi, Pierre Rucart, Manj S Sandhu, Patrick R Shea, Hanneke Schuitemaker, Ioannis Theodorou, Fredrik Vannberg, Jan Veldink, Bruce D Walker, Amy Weintrob, Cheryl A Winkler, Steven Wolinsky, Amalio Telenti, David B Goldstein, Paul I W de Bakker, Jean-François Zagury, Jacques Fellay
Publikováno v:
PLoS Pathogens, Vol 9, Iss 7, p e1003515 (2013)
Multiple genome-wide association studies (GWAS) have been performed in HIV-1 infected individuals, identifying common genetic influences on viral control and disease course. Similarly, common genetic correlates of acquisition of HIV-1 after exposure
Externí odkaz:
https://doaj.org/article/8b487ebc53ca4a4eae671f4a5970e634
Autor:
Maria Nikolova, Matthieu Carriere, Mohammad-Ali Jenabian, Sophie Limou, Mehwish Younas, Ayrin Kök, Sophie Huë, Nabila Seddiki, Anne Hulin, Olivier Delaneau, Hanneke Schuitemaker, Joshua T Herbeck, James I Mullins, Maria Muhtarova, Armand Bensussan, Jean-François Zagury, Jean-Daniel Lelievre, Yves Lévy
Publikováno v:
PLoS Pathogens, Vol 7, Iss 7, p e1002110 (2011)
HIV-1 infection is characterized by a chronic activation of the immune system and suppressed function of T lymphocytes. Regulatory CD4+ CD25(high) FoxP3+CD127(low) T cells (Treg) play a key role in both conditions. Here, we show that HIV-1 positive p
Externí odkaz:
https://doaj.org/article/6978a6a1af86471db9fda97b11c647d1
Autor:
Sebastiaan M Bol, Perry D Moerland, Sophie Limou, Yvonne van Remmerden, Cédric Coulonges, Daniëlle van Manen, Joshua T Herbeck, Jacques Fellay, Margit Sieberer, Jantine G Sietzema, Ruben van 't Slot, Jeremy Martinson, Jean-François Zagury, Hanneke Schuitemaker, Angélique B van 't Wout
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e17190 (2011)
HIV-1 infected macrophages play an important role in rendering resting T cells permissive for infection, in spreading HIV-1 to T cells, and in the pathogenesis of AIDS dementia. During highly active anti-retroviral treatment (HAART), macrophages keep
Externí odkaz:
https://doaj.org/article/ec933f9d95a943fd86decd23dded18ac
Autor:
Joshua T Herbeck, Geoffrey S Gottlieb, Kim Wong, Roger Detels, John P Phair, Charles R Rinaldo, Lisa P Jacobson, Joseph B Margolick, James I Mullins
Publikováno v:
PLoS ONE, Vol 4, Iss 9, p e6915 (2009)
BACKGROUND:As availability of primary cells can be limited for genetic studies of human disease, lymphoblastoid cell lines (LCL) are common sources of genomic DNA. LCL are created in a transformation process that entails in vitro infection of human B
Externí odkaz:
https://doaj.org/article/ce26b8494bf8435383c20a6a957974fc
Autor:
Joshua T Herbeck, Geoffrey S Gottlieb, Xiuhong Li, Zheng Hu, Roger Detels, John Phair, Charles Rinaldo, Lisa P Jacobson, Joseph B Margolick, James I Mullins
Publikováno v:
PLoS ONE, Vol 3, Iss 2, p e1525 (2008)
Several long-term cohort studies and in-vitro fitness assays have resulted in inconsistent reports on changes in HIV-1 virulence, including reports of decreasing, stable, and increasing virulence over the course of the AIDS pandemic. We tested the hy
Externí odkaz:
https://doaj.org/article/e84e929123ae44b2a42398def6e59040
Autor:
Sai Win Kyaw Htet Aung, Hanley Kingston, Loice W. Mbogo, Betsy Sambai, Aliza Monroe-Wise, Natasha T. Ludwig-Barron, David Bukusi, William Sinkele, Esther Gitau, Sarah Masyuko, Joshua T. Herbeck, Carey Farquhar, Brandon L. Guthrie
Publikováno v:
Harm Reduction Journal, Vol 20, Iss 1, Pp 1-14 (2023)
Abstract Background In Kenya, violence is common among people who inject drugs (PWID) living with HIV and their sexual and injecting partners and may lead to decreased uptake of HIV services, increased HIV risk behaviors, and increased HIV transmissi
Externí odkaz:
https://doaj.org/article/6e9e4720901b43c6bb91c2b14f91c575
Autor:
Shradha Doshi, Hanley Kingston, Ashley S. Tseng, Bhavna H. Chohan, Betsy Sambai, Brandon L. Guthrie, Aliza Monroe-Wise, Loice W. Mbogo, Sarah Masyuko, Khai Hoan Tram, William Sinkele, Paul Macharia, David Bukusi, Joshua T. Herbeck, Carey Farquhar
Publikováno v:
Harm Reduction Journal, Vol 20, Iss 1, Pp 1-9 (2023)
Abstract Background In sub-Saharan Africa many people who inject drugs (PWID) are living with undiagnosed or untreated HIV and experience high levels of poverty and conditions that can contribute to worse outcomes from SARS-CoV-2 infection. Identifyi
Externí odkaz:
https://doaj.org/article/4f5294bd737b4b43a7f0e0ddaa266cac