Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Joshua Schustak"'
Autor:
Michael Twarog, Joshua Schustak, YongYao Xu, Matthew Coble, Katie Dolan, Robert Esterberg, Qian Huang, Magali Saint-Geniez, Yi Bao
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Increasing evidence suggests that chronic inflammation plays an important role in the pathogenesis of age-related macular degeneration (AMD); however, the precise pathogenic stressors and sensors, and their impact on disease progression rema
Externí odkaz:
https://doaj.org/article/c705bd4509e74127925f63bc280d986c
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0301239 (2024)
The retinal pigment epithelium (RPE) is essential to maintain retinal function, and RPE cell death represents a key pathogenic stage in the progression of several blinding ocular diseases, including age-related macular degeneration (AMD). To identify
Externí odkaz:
https://doaj.org/article/e9f868a54af74dfdac6d332528ec960f
Publikováno v:
Journal of Immunology Research, Vol 2021 (2021)
Age-related macular degeneration (AMD), a degenerative disease of the outer retina, is the leading cause of blindness among the elderly. A hallmark of geographic atrophy (GA), an advanced type of nonneovascular AMD (dry AMD), is photoreceptor and ret
Externí odkaz:
https://doaj.org/article/feb4a8d30dc042da87508f4e98666dee
Publikováno v:
Journal of Immunology Research
Journal of Immunology Research, Vol 2021 (2021)
Journal of Immunology Research, Vol 2021 (2021)
Age-related macular degeneration (AMD), a degenerative disease of the outer retina, is the leading cause of blindness among the elderly. A hallmark of geographic atrophy (GA), an advanced type of nonneovascular AMD (dry AMD), is photoreceptor and ret
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8157c753060a844c66e71bb92893505e
https://doi.org/10.1155/2021/9975628
https://doi.org/10.1155/2021/9975628
Autor:
Brook Brouha, Joshua Schustak, Alexander H. Farley, John V. Moran, Haig H. Kazazian, Sheila Lutz-Prigge, Richard M. Badge
Publikováno v:
Proceedings of the National Academy of Sciences. 100:5280-5285
Although LINE-1 (long interspersed nucleotide element-1, L1) retrotransposons comprise 17% of the human genome, an exhaustive search of the December 2001 “freeze” of the haploid human genome working draft sequence (95% complete) yielded only 90 L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a3b96bed8582098f8e983c13078e4c5
https://doi.org/10.1073/pnas.0831042100
https://doi.org/10.1073/pnas.0831042100
The mechanisms controlling the formation of synaptic connections between muscle spindle afferents and spinal motor neurons are believed to be regulated by factors originating from muscle spindles. Here, we find that the connections form with appropri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac4091127fbca5185455555bbcc63c49
https://europepmc.org/articles/PMC2739048/
https://europepmc.org/articles/PMC2739048/
Autor:
Richard O. Hynes, Phillip A. Sharp, Patrick Stern, Stefan J. Erkeland, Sophie Astrof, Joshua Schustak
We report a system for Cre-regulated expression of RNA interference in vivo . Expression cassettes comprise selectable and FACS-sortable markers in tandem with additional marker genes and shRNAs in the antisense orientation. The cassettes are flanked
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ce721fe9eef360b4fdcd988859003cc
https://europepmc.org/articles/PMC2532697/
https://europepmc.org/articles/PMC2532697/