Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Joshua S. Ostrander"'
Autor:
Erin R. Birdsall, Vivek Saraswat, Joshua S. Ostrander, Benjamin R. Feingold, Michael S. Arnold, Justin P. Lomont, Martin T. Zanni, Megan K. Petti, Kacie L. Rich
Publikováno v:
The Journal of Physical Chemistry Letters. 10:3836-3842
Immunosensors use antibodies to detect and quantify biomarkers of disease, though the sensors often lack structural information. We create a surface-sensitive two-dimensional infrared (2D IR) spectroscopic immunosensor for studying protein structures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b406f83a8302e8bc73d58bb75371ce33
https://doi.org/10.1021/acs.jpclett.9b01267
https://doi.org/10.1021/acs.jpclett.9b01267
Publikováno v:
Proceedings of the National Academy of Sciences. 116:6602-6607
UV light and other factors damage crystallin proteins in the eye lens, resulting in cataracts that scatter light and affect vision. Little information exists about protein structures within these disease-causing aggregates. We examined postmortem len
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d24f83ee1fdf8f7629cf7078f6b6a39
https://doi.org/10.1073/pnas.1821534116
https://doi.org/10.1073/pnas.1821534116
Autor:
Vivek Saraswat, Joshua S. Ostrander, Erin R. Birdsall, Megan K. Petti, Martin T. Zanni, Michael S. Arnold
Publikováno v:
J Phys Chem Lett
The structures of many membrane-bound proteins and polypeptides depend on the membrane potential. However, spectroscopically studying their structures under an applied field is challenging, because a potential is difficult to generate across more tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b7403b7e1f5660e82682c658759b22a
https://europepmc.org/articles/PMC8162810/
https://europepmc.org/articles/PMC8162810/
Autor:
Miriam Bohlmann Kunz, Megan K. Petti, Ariel M. Alperstein, Joshua S. Ostrander, Zachary T Armstrong, Erin R. Birdsall, Martin T. Zanni
Publikováno v:
J Phys Chem A
Surfaces and interfaces are ubiquitous in nature. From cell membranes, to photovoltaic thin films, surfaces have important function in both biological and materials systems. Spectroscopic techniques have been developed to probe systems like these, su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb092b3e67d6c5f22c9c61ed59d2b297
https://europepmc.org/articles/PMC7993518/
https://europepmc.org/articles/PMC7993518/
Autor:
Vivek Saraswat, Joshua S. Ostrander, Martin T. Zanni, Michael S. Arnold, Courtney L. Hummell, Austin J. Way, Jialiang Wang, Robert M. Jacobberger
Publikováno v:
ACS Nano. 12:7855-7865
Laminates made of graphene oxide nanosheets have been shown to exhibit high water permeance and salt rejection and, therefore, have generated immense interest from the scientific community due to their potential in separation applications. However, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00954996327f1d0d5e20080f44cb0f93
https://doi.org/10.1021/acsnano.8b02015
https://doi.org/10.1021/acsnano.8b02015
Publikováno v:
The Journal of Physical Chemistry B. 121:8935-8945
We report the transition dipole strengths and frequencies of the amyloid β-sheet amide I mode for the aggregated proteins amyloid-β1–40, calcitonin, α-synuclein, and glucagon. According to standard vibrational coupling models for proteins, the f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94e804b3ee4a04e5542ac7f413f4525a
https://doi.org/10.1021/acs.jpcb.7b06826
https://doi.org/10.1021/acs.jpcb.7b06826
Autor:
Michał Maj, Justin P. Lomont, Joshua S. Ostrander, Kacie L. Rich, Martin T. Zanni, Jia-Jung Ho
We use two-dimensional IR (2D IR) spectroscopy to explore fibril formation for the two predominant isoforms of the β-amyloid (Aβ1–40 and Aβ1–42) protein associated with Alzheimer’s disease. Two-dimensional IR spectra resolve a transition at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51797c2de6970ce7ad9332c468ad0626
https://europepmc.org/articles/PMC5969533/
https://europepmc.org/articles/PMC5969533/
Autor:
Darcie Farrow, Alexander S. Tappan, Robert Knepper, Martin T. Zanni, Jeffery Kay, Joshua S. Ostrander
Publikováno v:
The journal of physical chemistry. B. 121(6)
Pentaerythritol tetranitrate (PETN) is a common secondary explosive and has been used extensively to study shock initiation and energy propagation in energetic materials. We report 2D IR measurements of PETN thin films that resolve vibrational energy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbbb92571d66cbf7170910fa51224631
https://pubmed.ncbi.nlm.nih.gov/28099029
https://pubmed.ncbi.nlm.nih.gov/28099029
Publikováno v:
Chemical reviews. 117(16)
Proteins exhibit structural fluctuations over decades of time scales. From the picosecond side chain motions to aggregates that form over the course of minutes, characterizing protein structure over these vast lengths of time is important to understa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3d638c7882b516834b26b10901ec33d
https://pubmed.ncbi.nlm.nih.gov/28060489
https://pubmed.ncbi.nlm.nih.gov/28060489
Autor:
Kacie L. Rich, Michael S. Arnold, Martin T. Zanni, Vivek Saraswat, Joshua S. Ostrander, Justin P. Lomont, Megan K. Petti, Erin R. Birdsall
Publikováno v:
The Journal of Chemical Physics. 150:024707
Spectroscopic techniques that are capable of measuring surfaces and interfaces must overcome two technical challenges: one, the low coverage of molecules at the surface, and two, discerning between signals from the bulk and surface. We present surfac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5dae726deec8051f3e7c605848b014e
https://doi.org/10.1063/1.5065511
https://doi.org/10.1063/1.5065511