Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Joshua S Speed"'
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26063 (2011)
The renal medullary endothelin (ET-1) system plays an important role in the control of sodium excretion and arterial pressure (AP) through the activation of renal medullary ET-B receptors. We have previously shown that blockade of endothelin type B r
Externí odkaz:
https://doaj.org/article/449adb1724a54bf5bcd54e8b303a07ac
Autor:
Pallabi Pal, Abelardo Medina, Sheetal Chowdhury, Courtney A. Cates, Ratna Bollavarapu, Jon M. Person, Benjamin McIntyre, Joshua S. Speed, Amol V. Janorkar
Publikováno v:
Biomedicines, Vol 12, Iss 5, p 997 (2024)
Clinical and basic science applications using adipose-derived stem cells (ADSCs) are gaining popularity. The current adipose tissue harvesting procedures introduce nonphysiological conditions, which may affect the overall performance of the isolated
Externí odkaz:
https://doaj.org/article/7ad55f89a1a54213a06c86d66a867bcf
Autor:
Eman Y. Gohar, Carmen De Miguel, Ijeoma E. Obi, Elizabeth M. Daugherty, Kelly A. Hyndman, Bryan K. Becker, Chunhua Jin, Randee Sedaka, Jermaine G. Johnston, Pengyuan Liu, Joshua S. Speed, Tanecia Mitchell, Alison J. Kriegel, Jennifer S. Pollock, David M. Pollock
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 5 (2022)
Background Premenopausal women are less likely to develop hypertension and salt‐related complications than are men, yet the impact of sex on mechanisms regulating Na+ homeostasis during dietary salt challenges is poorly defined. Here, we determined
Externí odkaz:
https://doaj.org/article/0cb3e71087914936a984fb5185dc2cdf
Publikováno v:
Clinical Science. 137:769-772
Despite the overwhelming evidence that the kidney is the principal regulator of chronic blood pressure though the ability to sense pressure and adjust blood volume accordingly, recent clinical and preclinical evidence suggests that skin clearance of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b640c5fc465f349f23a9a0edc9602d6
https://doi.org/10.1042/cs20230163
https://doi.org/10.1042/cs20230163
Autor:
Kelly A. Hyndman, Joshua S. Speed, Luciano D. Mendoza, John M. Allan, Jackson Colson, Randee Sedaka, Chunhua Jin, Hyun Jun Jung, Samir El-Dahr, David M. Pollock, Jennifer S. Pollock
Publikováno v:
JCI Insight, Vol 5, Iss 16 (2020)
Histone deacetylase (HDAC) enzymes regulate transcription through epigenetic modification of chromatin structure, but their specific functions in the kidney remain elusive. We discovered that the human kidney expresses class I HDACs. Kidney medulla-s
Externí odkaz:
https://doaj.org/article/70882cc23e384efc94408f6a164a8b54
Publikováno v:
Can J Physiol Pharmacol
Our lab recently reported that the blockade of endothelin-1 (ET-1) receptors attenuates insulin resistance in obese mice; therefore, we hypothesized that patients taking ET-1 receptor antagonists (ERAs) will have improved glycemic control. University
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8814ff3abd71a1309386ddb27f63d181
https://doi.org/10.1139/cjpp-2022-0132
https://doi.org/10.1139/cjpp-2022-0132
Autor:
Megan K. Rhoads, Joshua S. Speed, Kaehler J. Roth, Dingguo Zhang, Chunhua Jin, Karen L. Gamble, David M. Pollock
Publikováno v:
Am J Physiol Renal Physiol
Night shift work increases risk of cardiovascular disease associated with an irregular eating schedule. Elevating this risk is the high level of salt intake observed in the typical Western diet. Renal Na(+) excretion has a distinct diurnal pattern, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af8228484e0577b8c016eb02df136efc
https://pubmed.ncbi.nlm.nih.gov/35100821
https://pubmed.ncbi.nlm.nih.gov/35100821
Autor:
Jerry D. Monroe, Satya A. Moolani, Elvin N. Irihamye, Joshua S. Speed, Yann Gibert, Michael E. Smith
Publikováno v:
Cells, Vol 9, Iss 12, p 2637 (2020)
Phenanthriplatin is a new monofunctional platinum(II) complex that binds only one strand of DNA and acts by blocking gene transcription, but its effect on gene regulation has not been characterized relative to the traditional platinum-based complex,
Externí odkaz:
https://doaj.org/article/c86c9c67c3ee4651aea797a72875d20f
Publikováno v:
American journal of physiology. Endocrinology and metabolism.
Endothelin-1 (ET-1) is elevated in patients with systemic lupus erythematosus (SLE), an autoimmune disease characterized by high rates of hypertension, renal injury, and cardiovascular disease. SLE is also associated with increased prevalence of obes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::175d7f7f083beaa6ca726341bb0bc600
https://pubmed.ncbi.nlm.nih.gov/36476039
https://pubmed.ncbi.nlm.nih.gov/36476039
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b7c5453b19ee5b8f1192fc25bcf95f3
https://doi.org/10.1096/fasebj.2022.36.s1.l8015
https://doi.org/10.1096/fasebj.2022.36.s1.l8015