Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Joshua R. Sacher"'
Autor:
Tanja Krainz, Michael M. Gaschler, Chaemin Lim, Joshua R. Sacher, Brent R. Stockwell, Peter Wipf
Publikováno v:
ACS Central Science, Vol 2, Iss 9, Pp 653-659 (2016)
Externí odkaz:
https://doaj.org/article/b6a7bc61845048079b5d98232cfd38dc
Autor:
Alejandro Gutierrez, Lukas E. Dow, Kimmie Ng, Marios Giannakis, Ewa Sicinska, Chen Yuan, Martin Stanulla, Florence Wagner, Joshua R. Sacher, Connor McGuckin, Salmaan Karim, Sabine Schreek, Emma M. Schatoff, Teng Han, James Degar, Roxane Labrosse, Laura Hinze
Supplementary Table 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17b33c396e6eddd4fc3c1bf1992633b6
https://doi.org/10.1158/2159-8290.22534993.v1
https://doi.org/10.1158/2159-8290.22534993.v1
Autor:
Alejandro Gutierrez, Lukas E. Dow, Kimmie Ng, Marios Giannakis, Ewa Sicinska, Chen Yuan, Martin Stanulla, Florence Wagner, Joshua R. Sacher, Connor McGuckin, Salmaan Karim, Sabine Schreek, Emma M. Schatoff, Teng Han, James Degar, Roxane Labrosse, Laura Hinze
Supplementary Figures S1-S11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::783fdd4ad1088ca6401c78956bbb409f
https://doi.org/10.1158/2159-8290.22534999.v1
https://doi.org/10.1158/2159-8290.22534999.v1
Autor:
Alejandro Gutierrez, Lukas E. Dow, Kimmie Ng, Marios Giannakis, Ewa Sicinska, Chen Yuan, Martin Stanulla, Florence Wagner, Joshua R. Sacher, Connor McGuckin, Salmaan Karim, Sabine Schreek, Emma M. Schatoff, Teng Han, James Degar, Roxane Labrosse, Laura Hinze
Colorectal cancer is driven by mutations that activate canonical WNT/β-catenin signaling, but inhibiting WNT has significant on-target toxicity, and there are no approved therapies targeting dominant oncogenic drivers. We recently found that activat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3aa49176de370c6f0d97ccfed657309c
https://doi.org/10.1158/2159-8290.c.6547729.v1
https://doi.org/10.1158/2159-8290.c.6547729.v1
Autor:
Yan-Ling Zhang, Sean P. Moran, Andrew Allen, David Baez-Nieto, Qihong Xu, Lei A. Wang, William E. Martenis, Joshua R. Sacher, Jennifer P. Gale, Michel Weïwer, Florence F. Wagner, Jen Q. Pan
Publikováno v:
ACS Pharmacology & Translational Science. 5:156-168
T-type voltage-gated Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44f35b400e15284ba039540821b45741
https://doi.org/10.1021/acsptsci.1c00233
https://doi.org/10.1021/acsptsci.1c00233
Autor:
Sonia M Vallabh, Arthur J. Campbell, Jayme L. Dahlin, Michael F. Mesleh, Kong T. Nguyen, Dominick Casalena, S. Kirk Wright, Dmitry L. Usanov, Christopher T. Lemke, Jamie A. Moroco, Joshua R. Sacher, Andrew G. Reidenbach, Murugappan Sathappa, Om K. Shrestha, Eric Vallabh Minikel, Jenna B. Yehl, Douglas S. Auld, Stuart L. Schreiber, V.L. Rangel, Alix I. Chan, Rishi N. Shah, Maria Cristina Nonato, David R. Liu, Florence F. Wagner, Alison Leed, Virendar K. Kaushik
Publikováno v:
J Biol Chem
Prion disease is a rapidly progressive neurodegenerative disorder caused by misfolding and aggregation of the prion protein (PrP), and there are currently no therapeutic options. PrP ligands could theoretically antagonize prion formation by protectin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec8fc34d169f5f23f5d3171c3a119372
https://doi.org/10.1074/jbc.ra120.014905
https://doi.org/10.1074/jbc.ra120.014905
Autor:
Lawrence M. Pfeffer, Joshua R. Sacher, Yinan Wang, Chuanhe Yang, Michelle Sims, Yali He, Duane D. Miller
Publikováno v:
Bioorganicmedicinal chemistry. 53
Glioblastoma (GBM) is the most aggressive and treatment-refractory malignant adult brain cancer. After standard of care therapy, the overall median survival for GBM is only ∼6 months with a 5-year survival10%. Although some patients initially respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f736246339ec96fb87e4050fca500915
https://pubmed.ncbi.nlm.nih.gov/34863065
https://pubmed.ncbi.nlm.nih.gov/34863065
Autor:
Mohammad H. Rohban, Ashley M. Fuller, Ceryl Tan, Jonathan T. Goldstein, Deepsing Syangtan, Amos Gutnick, Ann DeVine, Madhura P. Nijsure, Megan Rigby, Joshua R. Sacher, Steven M. Corsello, Grace B. Peppler, Marta Bogaczynska, Andrew Boghossian, Gabrielle E. Ciotti, Allison T. Hands, Aroonroj Mekareeya, Minh Doan, Jennifer P. Gale, Rik Derynck, Thomas Turbyville, Joel D. Boerckel, Shantanu Singh, Laura L. Kiessling, Thomas L. Schwarz, Xaralabos Varelas, Florence F. Wagner, Ran Kafri, T.S. Karin Eisinger-Mathason, Anne E. Carpenter
Identifying chemical regulators of biological pathways is currently a time-consuming bottleneck in developing therapeutics and small-molecule research tools. Typically, thousands to millions of candidate small molecules are tested in target-based bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4fa998708d494bc5bb5f98affb1ae7d3
https://doi.org/10.1101/2021.07.29.454377
https://doi.org/10.1101/2021.07.29.454377
Publikováno v:
J Voice
Objectives/Hypothesis The objectives of this study were to (1) identify optimal clusters of 15 standard acoustic and aerodynamic voice metrics recommended by the American Speech-Language-Hearing Association (ASHA) to improve characterization of patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c9776e4a1a5434ee045d080720044a8
https://doi.org/10.1016/j.jvoice.2021.05.019
https://doi.org/10.1016/j.jvoice.2021.05.019