Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Joshua R. Barton"'
Autor:
Joshua R. Barton, Annie K. Londregan, Tyler D. Alexander, Ariana A. Entezari, Manuel Covarrubias, Scott A. Waldman
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Enteroendocrine cells (EECs) are an essential interface between the gut and brain that communicate signals about nutrients, pain, and even information from our microbiome. EECs are hormone-producing cells expressed throughout the gastrointestinal epi
Externí odkaz:
https://doaj.org/article/36f7e9c456064185939620f957592ed3
Autor:
Joshua R. Barton, Annie K. Londregan, Tyler D. Alexander, Ariana A. Entezari, Shely Bar-Ad, Lan Cheng, Angelo C. Lepore, Adam E. Snook, Manuel Covarrubias, Scott A. Waldman
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 4 (2023)
Visceral pain (VP) is a global problem with complex etiologies and limited therapeutic options. Guanylyl cyclase C (GUCY2C), an intestinal receptor producing cyclic GMP(cGMP), which regulates luminal fluid secretion, has emerged as a therapeutic targ
Externí odkaz:
https://doaj.org/article/6fcd4bf1e4cf498abeccb887b46d04f2
Autor:
John C. Flickinger, Ross E. Staudt, Jagmohan Singh, Robert D. Carlson, Joshua R. Barton, Trevor R. Baybutt, Jeffrey A. Rappaport, Alicja Zalewski, Amanda Pattison, Scott A. Waldman, Adam E. Snook
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-10 (2022)
Abstract Strategies to augment immunity to self/neoantigens expressed by cancers are urgently needed to expand the proportion of patients benefiting from immunotherapy, particularly for GI cancers where only a fraction of patients respond to immunoth
Externí odkaz:
https://doaj.org/article/e22b2a072d4641808bb7b166089c9d83
Autor:
John C. Flickinger, Jagmohan Singh, Yanki Yarman, Robert D. Carlson, Joshua R. Barton, Scott A. Waldman, Adam E. Snook
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The Gram-positive bacterium Listeria monocytogenes (Lm) is an emerging platform for cancer immunotherapy. To date, over 30 clinical trials have been initiated testing Lm cancer vaccines across a wide variety of cancers, including lung, cervical, colo
Externí odkaz:
https://doaj.org/article/f09e4fa5e7f24752a72ae498fa1d7fac
Publikováno v:
Encyclopedia of Cell Biology ISBN: 9780128216248
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccc2340481003896728f4a32eb498b06
https://doi.org/10.1016/b978-0-12-821618-7.00080-8
https://doi.org/10.1016/b978-0-12-821618-7.00080-8
Autor:
Joshua R. Barton, Annie K. Londregran, Tyler D. Alexander, Ariana A. Entezari, Shely Bar-Ad, Lan Cheng, Angelo C. Lepore, Adam E. Snook, Manuel Covarrubias, Scott A. Waldman
Publikováno v:
The Journal of clinical investigation.
Visceral pain (VP) is a global problem with complex etiologies and limited therapeutic options. Guanylyl cyclase C (GUCY2C), an intestinal receptor producing cyclic GMP which regulates luminal fluid secretion, has emerged as a therapeutic target for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6ae40062c5c97b8592da03df97a1492
https://pubmed.ncbi.nlm.nih.gov/36548082
https://pubmed.ncbi.nlm.nih.gov/36548082
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8b043db88f84d0f4529688636226173
https://doi.org/10.1096/fasebj.2022.36.s1.r4761
https://doi.org/10.1096/fasebj.2022.36.s1.r4761
Autor:
Scott A. Waldman, Amanda M. Pattison, Jeffrey A. Rappaport, Joshua R Barton, Alicja Zalewski, Adam E. Snook, Ariana A Entezari
Publikováno v:
Cancer Biology & Therapy. 21:799-805
Most sporadic colorectal cancer reflects acquired mutations in the adenomatous polyposis coli (APC) tumor suppressor gene, while germline heterozygosity for mutant APC produces the autosomal dominant disorder Familial Adenomatous Polyposis (FAP) with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad9c3d82c510340367fe6372d189e1ee
https://doi.org/10.1080/15384047.2020.1779005
https://doi.org/10.1080/15384047.2020.1779005
Publikováno v:
Expert Opin Drug Discov
INTRODUCTION. Obesity is a prevalent condition that accounts for significant morbidity and mortality across the globe. Despite substantial effort, most obesity pharmacotherapies have proven unsafe or ineffective. The use of obese mouse models provide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afb3c6a336541e484ff6b8b8cf57af70
https://pubmed.ncbi.nlm.nih.gov/33472452
https://pubmed.ncbi.nlm.nih.gov/33472452
Autor:
Joshua R Barton, John C. Flickinger, Jeffrey A. Rappaport, Trevor R. Baybutt, Amanda M. Pattison, Adam E. Snook, Scott A. Waldman
Publikováno v:
Biomark Med
Gastrointestinal cancers encompass a diverse class of tumors arising in the GI tract, including esophagus, stomach, pancreas and colorectum. Collectively, gastrointestinal cancers compose a high fraction of all cancer deaths, highlighting an unmet ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f8cb9a2c879e8667480f935b2f17f6b
https://europepmc.org/articles/PMC8293028/
https://europepmc.org/articles/PMC8293028/