Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Joshua R Hansen"'
Autor:
Mary S Dickinson, Lindsey N Anderson, Bobbie-Jo M Webb-Robertson, Joshua R Hansen, Richard D Smith, Aaron T Wright, Kevin Hybiske
Publikováno v:
PLoS Pathogens, Vol 15, Iss 4, p e1007698 (2019)
Chlamydia trachomatis is the most common cause of bacterial sexually transmitted infection, responsible for millions of infections each year. Despite this high prevalence, the elucidation of the molecular mechanisms of Chlamydia pathogenesis has been
Externí odkaz:
https://doaj.org/article/d80c2cfcc3d64ba490ed5b51081ae4ee
Autor:
Chelsea Hutchinson-Bunch, James A. Sanford, Joshua R. Hansen, Marina A. Gritsenko, Karin D. Rodland, Paul D. Piehowski, Wei-Jun Qian, Joshua N. Adkins
Publikováno v:
ACS Omega, Vol 6, Iss 19, Pp 12660-12666 (2021)
Externí odkaz:
https://doaj.org/article/a0c2d99cb63748148f287fd4e1bc44c5
Autor:
Tara K. Sigdel, Paul D. Piehowski, Sudeshna Roy, Juliane Liberto, Joshua R. Hansen, Adam C. Swensen, Rui Zhao, Ying Zhu, Priyanka Rashmi, Andrew Schroeder, Izabella Damm, Swastika Sur, Jinghui Luo, Yingbao Yang, Wei-Jun Qian, Minnie M. Sarwal
Publikováno v:
Frontiers in Medicine, Vol 7 (2021)
Externí odkaz:
https://doaj.org/article/88ed030302294d25b4e0f7673a3ddff6
Autor:
Tara K. Sigdel, Paul D. Piehowski, Sudeshna Roy, Juliane Liberto, Joshua R. Hansen, Adam C. Swensen, Rui Zhao, Ying Zhu, Priyanka Rashmi, Andrew Schroeder, Izabella Damm, Swastika Sur, Jinghui Luo, Yingbao Yang, Wei-Jun Qian, Minnie M. Sarwal, The Kidney Precision Medicine Project (KPMP) Consortium
Publikováno v:
Frontiers in Medicine, Vol 7 (2020)
Molecular assessments at the single cell level can accelerate biological research by providing detailed assessments of cellular organization and tissue heterogeneity in both disease and health. The human kidney has complex multi-cellular states with
Externí odkaz:
https://doaj.org/article/3732ec0f49974b1fabd73c81171d8162
Autor:
Paul D. Piehowski, Wei-Jun Qian, James A. Sanford, Joshua N. Adkins, Karin D. Rodland, Marina A. Gritsenko, Joshua R. Hansen, Chelsea Hutchinson-Bunch
Publikováno v:
ACS Omega, Vol 6, Iss 19, Pp 12660-12666 (2021)
ACS Omega
ACS Omega
Isobaric labeling via tandem mass tag (TMT) reagents enables sample multiplexing prior to LC-MS/MS, facilitating high-throughput large-scale quantitative proteomics. Consistent and efficient labeling reactions are essential to achieve robust quantifi
Autor:
Sara J. C. Gosline, Cristina Tognon, Michael Nestor, Sunil Joshi, Rucha Modak, Alisa Damnernsawad, Camilo Posso, Jamie Moon, Joshua R. Hansen, Chelsea Hutchinson-Bunch, James C. Pino, Marina A. Gritsenko, Karl K. Weitz, Elie Traer, Jeffrey Tyner, Brian Druker, Anupriya Agarwal, Paul Piehowski, Jason E. McDermott, Karin Rodland
Publikováno v:
Clinical Proteomics. 19
Acute Myeloid Leukemia (AML) affects 20,000 patients in the US annually with a five-year survival rate of approximately 25%. One reason for the low survival rate is the high prevalence of clonal evolution that gives rise to heterogeneous sub-populati
Autor:
James C. Pino, Camilo Posso, Sunil K. Joshi, Michael Nestor, Jamie Moon, Joshua R. Hansen, Marina A. Gritsenko, Chelsea Hutchinson-Bunch, Karl K. Weitz, Kevin Watanabe-Smith, Jason E. McDermott, Brian J. Druker, Tao Liu, Jeffrey W. Tyner, Anupriya Agarwal, Elie Traer, Paul D. Piehowski, Cristina E. Tognon, Karin D. Rodland, Sara J. Gosline
Publikováno v:
Cancer Research. 83:3172-3172
Acute myeloid leukemia (AML) is a deadly blood cancer that remains largely classified by genetic aberrations, which inform therapy stratification. However, therapeutic response cannot be predicted or explained by genetic abnormalities alone. The inte
Proteomics and Phosphoprotoemic Measurements Enhance Ability to Predict Ex Vivo Drug Response in AML
Autor:
Sara Gosline, Cristina Tognon, Michael Nestor, Sunil Joshi, Rucha Modak, Alisa Damnernsawad, Camilo Posso, Jamie Moon, Joshua R. Hansen, Chelsea Hutchinson-Bunch, James C Pino, Marina A. Gritsenko, Karl K. Weitz, Elie Traer, Jeffrey Tyner, Brian Druker, Anupriya Agarwal, Paul Piehowski, Jason E. McDermott, Karin Rodland
Acute Myeloid Leukemia (AML) affects 20,000 patients in the US annually with a five-year survival rate of approximately 25%. One reason for the low survival rate is the high prevalence of clonal evolution that gives rise to heterogeneous sub-populati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::690033e2a94538c9a72d87549e971271
https://doi.org/10.21203/rs.3.rs-1277906/v1
https://doi.org/10.21203/rs.3.rs-1277906/v1
Autor:
Marina A. Gritsenko, Paul D. Piehowski, Vladislav A. Petyuk, James A. Sanford, Brian J. Druker, Wei-Jun Qian, Karl K. Weitz, Karin D. Rodland, Tyler J. Sagendorf, Cristina E. Tognon, Tao Liu, Yang Wang, Joshua R. Hansen
Publikováno v:
Journal of the American Society for Mass Spectrometry
Global and phosphoproteome profiling has demonstrated great utility for the analysis of clinical specimens. One barrier to the broad clinical application of proteomic profiling is the large amount of biological material required, particularly for pho
Autor:
Roger E. De Filippo, Paolo Cravedi, Camille Nicolas Frank, Rui Zhao, Fadi Salem, Astgik Petrosyan, Kevin V. Lemley, Laura Perin, Valentina Villani, Xiaogang Hou, Joshua R. Hansen, Geremy Clair
Publikováno v:
Kidney international. 101(1)
Progression of glomerulosclerosis is associated with loss of podocytes with subsequent glomerular tuft instability. It is thought that a diminished number of podocytes may be able to preserve tuft stability through cell hypertrophy associated with ce