Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Joshua R D Pearson"'
Publikováno v:
FEBS Open Bio, Vol 13, Iss 7, Pp 1266-1277 (2023)
While useful for fundamental in vitro studies, monolayer cell cultures are not physiologically relevant. Spheroids, a complex three‐dimensional (3D) structure, more closely resemble in vivo tumor growth. Spheroids allow the results obtained relatin
Externí odkaz:
https://doaj.org/article/c5f976708f564b8989b4d05dc7b0ceae
Publikováno v:
Biomedicines, Vol 11, Iss 8, p 2100 (2023)
Immunotherapy represents an attractive avenue for cancer therapy due to its tumour specificity and relatively low frequency of adverse effects compared to other treatment modalities. Despite many advances being made in the field of cancer immunothera
Externí odkaz:
https://doaj.org/article/100563c7a4c142d3bfc557fff770979c
Autor:
Joshua R. D. Pearson, Stefania Cuzzubbo, Simon McArthur, Lindy G. Durrant, Jason Adhikaree, Chris J. Tinsley, A. Graham Pockley, Stephanie E. B. McArdle
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Glioblastoma multiforme (GBM) is the most frequently occurring primary brain tumor and has a very poor prognosis, with only around 5% of patients surviving for a period of 5 years or more after diagnosis. Despite aggressive multimodal therapy, consis
Externí odkaz:
https://doaj.org/article/6a7407adfcab4c87aab9894173687565
Autor:
Lindy G. Durrant, Stephanie E McArdle, Divya Nagarajan, Rachael L. Metheringham, Victoria A. Brentville, Joshua R D Pearson, A Graham Pockley
The management of patients with triple-negative breast cancer (TNBC) continues to pose a significant clinical challenge. Less than 30% of women with metastatic TNBC survive 5 years, despite adjuvant chemotherapy and the initial higher rates of clinic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c337b18e5ca31610cac6a97ae9fd2d6a
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-469698
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-469698
Autor:
Joshua R D Pearson, Shaymaa Ik. Al-Juboori, Michele Caraglia, Rukaia Almshayakhchi, Sarra Idri, David J. Boocock, Amanda K. Miles, Graham Ball, Jayakumar Vadakekolathu, Sarah Wagner, Tarik Regad, Vincenzo Desiderio, Dimitrios Zafeiris
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-14 (2019)
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research : CR
Background Metformin, a biguanide, is one of the most commonly prescribed treatments for type 2 diabetes and has recently been recommended as a potential drug candidate for advanced cancer therapy. Although Metformin has antiproliferative and proapop
Autor:
Joshua R D Pearson, Tarik Regad
Publikováno v:
Signal Transduction and Targeted Therapy
Glioblastoma multiforme (GBM) is a debilitating disease that is associated with poor prognosis, short median patient survival and a very limited response to therapies. GBM has a very complex pathogenesis that involves mutations and alterations of sev
Autor:
Victoria A. Brentville, Lindy G. Durrant, Joshua R D Pearson, Stephanie E. B. McArdle, Graham Pockley
Publikováno v:
Cancer Immunology Research. 7:B122-B122
Glioblastoma multiforme (GBM) is the most frequently occurring primary brain tumor; it is a debilitating disease that is associated with poor prognosis, short median patient survival and a limited response to current therapies. As a result, there is