Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Joshua Pan"'
Autor:
Xin Huang, Kyoung-mi Park, Paul Gontarz, Bo Zhang, Joshua Pan, Zachary McKenzie, Laura A. Fischer, Chen Dong, Sabine Dietmann, Xiaoyun Xing, Pavel V. Shliaha, Jihong Yang, Dan Li, Junjun Ding, Tenzin Lungjangwa, Maya Mitalipova, Shafqat A. Khan, Sumeth Imsoonthornruksa, Nick Jensen, Ting Wang, Cigall Kadoch, Rudolf Jaenisch, Jianlong Wang, Thorold W. Theunissen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Although the interactors of pluripotency factors have been identified in mouse embryonic stem cells (ESCs), their interactors in human ESCs remain unexplored. Here the authors map OCT4 protein interactions in naïve and primed human ESCs to find spec
Externí odkaz:
https://doaj.org/article/475ca4c998cb484bb6963209f6ebdc13
Autor:
Rita Sulahian, Jason J. Kwon, Katherine H. Walsh, Emma Pailler, Timothy L. Bosse, Maneesha Thaker, Diego Almanza, Joshua M. Dempster, Joshua Pan, Federica Piccioni, Nancy Dumont, Alfredo Gonzalez, Jonathan Rennhack, Behnam Nabet, John A. Bachman, Amy Goodale, Yenarae Lee, Mukta Bagul, Rosy Liao, Adrija Navarro, Tina L. Yuan, Raymond W.S. Ng, Srivatsan Raghavan, Nathanael S. Gray, Aviad Tsherniak, Francisca Vazquez, David E. Root, Ari J. Firestone, Jeff Settleman, William C. Hahn, Andrew J. Aguirre
Publikováno v:
Cell Reports, Vol 29, Iss 1, Pp 118-134.e8 (2019)
Summary: The mitogen-activated protein kinase (MAPK) pathway is a critical effector of oncogenic RAS signaling, and MAPK pathway inhibition may be an effective combination treatment strategy. We performed genome-scale loss-of-function CRISPR-Cas9 scr
Externí odkaz:
https://doaj.org/article/9a62a78ea0ee4966a7135dceb3c889af
Publikováno v:
Bioinformatics. 39
SummaryThe BioPlex project has created two proteome scale, cell-line-specific protein–protein interaction (PPI) networks: the first in 293T cells, including 120k interactions among 15k proteins; and the second in HCT116 cells, including 70k interac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c127708dad1d07d853c45d094ec906f
https://doi.org/10.1093/bioinformatics/btad091
https://doi.org/10.1093/bioinformatics/btad091
Autor:
Joshua Pan
Publikováno v:
Proceedings of the 2022 International Conference on Management of Data.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::372f099a246aa73403b27cfe4723bd53
https://doi.org/10.1145/3514221.3520256
https://doi.org/10.1145/3514221.3520256
Publikováno v:
2021 IEEE International Conference on Plasma Science (ICOPS).
Crossed-field devices (CFDs) use orthogonal magnetic and electric fields to generate reliable, cycloidal flows of electrons 1 . Individual CFDs may vary greatly in geometry and purpose, such as simple planar devices, slow wave structure radio-frequen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7954798790cb223b0c491bc270d9fd1f
https://doi.org/10.1109/icops36761.2021.9588472
https://doi.org/10.1109/icops36761.2021.9588472
Autor:
Rosy Liao, Joshua Pan, Raymond W.S. Ng, Federica Piccioni, Jonathan P. Rennhack, Ari J. Firestone, William C. Hahn, Amy Goodale, Diego Almanza, Andrew J. Aguirre, John A. Bachman, Emma Pailler, David E. Root, Srivatsan Raghavan, Tina L. Yuan, Mukta Bagul, Nathanael S. Gray, Alfredo Gonzalez, Yenarae Lee, Jason J. Kwon, Katherine H. Walsh, Nancy Dumont, Timothy L. Bosse, Behnam Nabet, Francisca Vazquez, Jeff Settleman, Aviad Tsherniak, Joshua M. Dempster, Adrija J. Navarro, Maneesha Thaker, Rita Sulahian
Publikováno v:
Cell Reports, Vol 29, Iss 1, Pp 118-134.e8 (2019)
Summary: The mitogen-activated protein kinase (MAPK) pathway is a critical effector of oncogenic RAS signaling, and MAPK pathway inhibition may be an effective combination treatment strategy. We performed genome-scale loss-of-function CRISPR-Cas9 scr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a01aa685e87c2fe16e8fa52aa6b0efad
http://www.sciencedirect.com/science/article/pii/S2211124719311520
http://www.sciencedirect.com/science/article/pii/S2211124719311520
Autor:
Andrew R. D’Avino, Zachary M. McKenzie, Roodolph St. Pierre, Nazar Mashtalir, Cigall Kadoch, Lu Wang, Joshua Pan, Ali Shilatifard, Caleb A. Lareau
Publikováno v:
Nature genetics
Perturbations to mammalian switch/sucrose non-fermentable (mSWI/SNF) chromatin remodeling complexes have been widely implicated as driving events in cancer1. One such perturbation is the dual loss of the SMARCA4 and SMARCA2 ATPase subunits in small c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03ac5aaf251af951dab7060ddfae1ad0
https://doi.org/10.1038/s41588-019-0363-5
https://doi.org/10.1038/s41588-019-0363-5
Autor:
Nick O Jensen, Maya Mitalipova, Jihong Yang, Xin Huang, Zachary M. McKenzie, Pavel V. Shliaha, Tenzin Lungjangwa, Cigall Kadoch, Sumeth Imsoonthornruksa, Xiaoyun Xing, Thorold W. Theunissen, Dan Li, Ting Wang, Chen Dong, Rudolf Jaenisch, Kyoung-mi Park, Shafqat Ali Khan, Sabine Dietmann, Junjun Ding, Jianlong Wang, Paul Gontarz, Laura A. Fischer, Joshua Pan, Bo Zhang
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Understanding the molecular underpinnings of pluripotency is a prerequisite for optimal maintenance and application of embryonic stem cells (ESCs). While the protein-protein interactions of core pluripotency factors have been identified in mouse ESCs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4704ae735085e5f0f05f17096ca08183
https://pubmed.ncbi.nlm.nih.gov/34446700
https://pubmed.ncbi.nlm.nih.gov/34446700
Autor:
Sipei Fu, Laura Pontano Vaites, Joe R. Cannon, Alexandra Panov, Ramin Rad, J. Wade Harper, Joshua Pan, Gabriela Zarraga, Sanjukta Guha Thakurta, Arvene Golbazi, Stanley Tam, Raphael J. Bruckner, Edward L. Huttlin, Hannah Parzen, John Szpyt, Keegan Stricker, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Kurt Baltier, Melanie P. Gygi, Fana Gebreab, Eila Maenpaa, Alexandra Thornock, Steven P. Gygi, José Navarrete-Perea
SUMMARYThousands of interactions assemble proteins into modules that impart spatial and functional organization to the cellular proteome. Through affinity-purification mass spectrometry, we have created two proteome-scale, cell-line-specific interact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b92863dd46f2652ee366b11711fd786
Autor:
Cigall Kadoch, Zhou Qianhe, Luis M. Soares, Caleb A. Lareau, Hayley J. Zullow, David Remillard, Nathanael S. Gray, Joshua Pan, Zachary M. McKenzie, Seth H. Cassel, Andrew R. D’Avino, Ho Man Chan, Alfredo M. Valencia, Brittany C. Michel, Matthew J. McBride, Nazar Mashtalir, Nora Fortoul, Michael Bocker, James E. Bradner
Publikováno v:
Nature cell biology
Mammalian SWI/SNF chromatin remodelling complexes exist in three distinct, final-form assemblies: canonical BAF (cBAF), PBAF and a newly characterized non-canonical complex (ncBAF). However, their complex-specific targeting on chromatin, functions an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d19d33f130f9337beb96395c3cbe5fa
http://europepmc.org/articles/PMC6698386
http://europepmc.org/articles/PMC6698386