Life‐long exercise training and inherited aerobic endurance capacity produce converging gut microbiome signatures in rodents

Autor: Fernando F. Anhê, Soumaya Zlitni, Nicole G. Barra, Kevin P. Foley, Mats I. Nilsson, Joshua P. Nederveen, Lauren G. Koch, Steven L. Britton, Mark A. Tarnopolsky, Jonathan D. Schertzer

Publikováno v: Physiological Reports, Vol 10, Iss 5, Pp n/a-n/a (2022)

Abstract High aerobic endurance capacity can be acquired by training and/or inherited. Aerobic exercise training (AET) and aging are linked to altered gut microbiome composition, but it is unknown if the environmental stress of exercise and host gene

Externí odkaz: https://doaj.org/article/d6b7b4c6e9f640569de57fe79f1af509

Muscle fiber capillarization as determining factor on indices of insulin sensitivity in humans

Autor: Tim Snijders, Joshua P. Nederveen, Lex B. Verdijk, Alfons J. H. M. Houben, Gijs H. Goossens, Gianna Parise, Luc J. C. vanLoon

Publikováno v: Physiological Reports, Vol 5, Iss 10, Pp n/a-n/a (2017)

Abstract To investigate the association between muscle fiber capillarization and indices of insulin sensitivity in healthy older adults. A skeletal muscle biopsy was taken from the m. vastus lateralis of 22 healthy (nondiabetic) male older adults. In

Externí odkaz: https://doaj.org/article/cc185da194ea4a288005e489c7515547

The Acute Effect of Multi-Ingredient Antioxidant Supplementation following Ionizing Radiation

Autor: Donald Xhuti, Irena A. Rebalka, Mahek Minhas, Linda May, Kieran Murphy, Joshua P. Nederveen, Mark A. Tarnopolsky

Publikováno v: Nutrients; Volume 15; Issue 1; Pages: 207

Radiation exposure is an undeniable health threat encountered in various occupations and procedures. High energy waves in ionizing radiation cause DNA damage and induce reactive oxygen species (ROS) production, which further exacerbate DNA, protein,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79f28d1e11628022a3d34a746a582626

The phosphorylation of AMPKβ1 is critical for increasing autophagy and maintaining mitochondrial homeostasis in response to fatty acids

Autor: Eric M. Desjardins, Brennan K. Smith, Emily A. Day, Serge Ducommun, Matthew J. Sanders, Joshua P. Nederveen, Rebecca J. Ford, Stephen L. Pinkosky, Logan K. Townsend, Robert M. Gutgesell, Rachel Lu, Kei Sakamoto, Gregory R. Steinberg

Publikováno v: Desjardins, E M, Smith, B K, Day, E A, Ducommun, S, Sanders, M J, Nederveen, J P, Ford, R J, Pinkosky, S L, Townsend, L K, Gutgesell, R M, Lu, R, Sakamoto, K & Steinberg, G R 2022, ' The phosphorylation of AMPKβ1 is critical for increasing autophagy and maintaining mitochondrial homeostasis in response to fatty acids ', Proceedings of the National Academy of Sciences of the United States of America, vol. 119, no. 48, e2119824119 . https://doi.org/10.1073/pnas.2119824119

Fatty acids are vital for the survival of eukaryotes, but when present in excess can have deleterious consequences. The AMP-activated protein kinase (AMPK) is an important regulator of multiple branches of metabolism. Studies in purified enzyme prepa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59ff00af91b3737ddb124470677dad36
https://pubmed.ncbi.nlm.nih.gov/36409897

Effects of a 6-wk Sprint Interval Training Protocol at Different Altitudes on Circulating Extracellular Vesicles

Autor: GEOFFREY WARNIER, ESTELLE DE GROOTE, OPHÉLIE DELCORTE, DANIEL NICOLAS MARTINEZ, JOSHUA P. NEDERVEEN, MATS I. NILSSON, MARC FRANCAUX, CHRISTOPHE E. PIERREUX, LOUISE DELDICQUE

Publikováno v: Medicine and science in sports and exercise, Vol. 55, no. 1, p. 46-54 (2022)

This study aimed to investigate the modulation of circulating exosome-like extracellular vesicles (ELVs) after 6 wk of sprint interval training (SIT) at sea level and at 2000, 3000, and 4000 m.Thirty trained endurance male athletes (18-35 yr) partici

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffbe951bcbd157824226b909ec12af67
https://pubmed.ncbi.nlm.nih.gov/36069865