Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Joshua P. Morgan"'
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 9, Pp 9867-9880 (2024)
Mitochondrial damage occurs in human trabecular meshwork (HTM) cells as a result of normal aging and in open angle glaucoma. Using an HTM cell model, we quantified mitochondrial function and ATP generation rates after dexamethasone (Dex) and TGF-β2
Externí odkaz:
https://doaj.org/article/ef9623406f044059974016278b28553e
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Human adipose-derived stem cell (ASC) grafts have emerged as a powerful tool in regenerative medicine. However, ASC therapeutic potential is hindered by stressors throughout their use. Here we demonstrate the transgenic expression of the tar
Externí odkaz:
https://doaj.org/article/882ff0a8c3a74589855cc0d95b2f18bf
Autor:
Jennifer M. Cassano, Brian C. Leonard, Bianca C. Martins, Natalia Vapniarsky, Joshua T. Morgan, Steven W. Dow, Kathryn L. Wotman, Lynn M. Pezzanite
Publikováno v:
Frontiers in Veterinary Science, Vol 10 (2023)
IntroductionEquine recurrent uveitis (ERU), an immune mediated disease characterized by repeated episodes of intra-ocular inflammation, affects 25% of horses in the USA and is the most common cause of glaucoma, cataracts, and blindness. Mesenchymal s
Externí odkaz:
https://doaj.org/article/0252252328f74913b99f500e42780664
Autor:
Zhikai Liu, David G. C. Hildebrand, Joshua L. Morgan, Yizhen Jia, Nicholas Slimmon, Martha W. Bagnall
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
How sensory systems are organized during development remains unclear. Here, the authors used electron microscopy to examine the gravity-sensing system in zebrafish, finding that directional tuning and developmental age are organizing principles of th
Externí odkaz:
https://doaj.org/article/24d7eea3a1b74b4db790f69db714a63b
Publikováno v:
BioTechniques, Vol 72, Iss 5, Pp 194-200 (2022)
Human skin equivalents (HSEs) are in vitro models of human skin. They are used to study skin development, diseases, wound healing and toxicity. The gold standard of analysis is histological sectioning, which both limits three-dimensional assessment o
Externí odkaz:
https://doaj.org/article/790fcf879df949da936047d2e971aece
Autor:
Sang-In Kim, Shyambabu Chaurasiya, Venkatesh Sivanandam, Seonah Kang, Anthony K. Park, Jianming Lu, Annie Yang, Zhifang Zhang, Isabella A. Bagdasarian, Yanghee Woo, Joshua T. Morgan, Zhirong Yin, Yuman Fong, Susanne G. Warner
Publikováno v:
Molecular Therapy: Oncolytics, Vol 24, Iss , Pp 864-872 (2022)
Pancreatic cancer resistance to immunotherapies is partly due to deficits in tumor-infiltrating immune cells and stromal density. Combination therapies that modify stroma and recruit immune cells are needed. Vitamin D analogs such as calcipotriol (Ca
Externí odkaz:
https://doaj.org/article/b5d91ed5c6a549feb97cb488438d4bd7
Publikováno v:
PLoS ONE, Vol 18, Iss 11 (2023)
Externí odkaz:
https://doaj.org/article/f24f6077287542a183ca6d871c671918
Publikováno v:
Biomolecules, Vol 12, Iss 12, p 1828 (2022)
Photoaging is an important extrinsic aging factor leading to altered skin morphology and reduced function. Prior work has revealed a connection between photoaging and loss of subcutaneous fat. Currently, primary models for studying this are in vivo (
Externí odkaz:
https://doaj.org/article/1a4d48020e854b0e8832ae38c37f13e9
Publikováno v:
MethodsX, Vol 6, Iss , Pp 1907-1918 (2019)
One of the largest issues facing the field of tissue engineering is scaling due to tissue necrosis as a result of a lack of vascularization. We have developed an accessible method for generating large scale vascular networks of arbitrary geometries t
Externí odkaz:
https://doaj.org/article/763b3f88d1d3458b8898d1972ee42d2d
Autor:
Joshua T. Morgan, Alan K. Robbins, Abigail B. Mateson, Kazuki Sawamoto, Shunji Tomatsu, Dione R. Gray, Jason P. Gleghorn, Julia Spencer Barthold
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
Background: The process of testicular descent requires androgen and insulin-like 3, hormones secreted by fetal Leydig cells. Knowledge concerning distinct and common functions of these hormones in regulating development of the fetal gubernaculum rema
Externí odkaz:
https://doaj.org/article/7ea62aef21244721bb55f93c83c4e021