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pro vyhledávání: '"Joshua Osuofa"'
Autor:
Joshua Osuofa, Scott M. Husson
Publikováno v:
Polymers, Vol 16, Iss 2, p 239 (2024)
The development of convective technologies for antibody purification is of interest to the bioprocessing industries. This study developed a Protein A membrane using a combination of graft polymerization and copper(I)-catalyzed alkyne–azide click ch
Externí odkaz:
https://doaj.org/article/39118961988245b28a6e14a359d82498
Autor:
Joshua Osuofa, Scott M. Husson
Publikováno v:
Membranes, Vol 13, Iss 10, p 824 (2023)
Protein A chromatography is the preferred unit operation for purifying Fc-based proteins. Convective chromatography technologies, like membrane adsorbers, can perform the purification rapidly and improve throughput dramatically. While the literature
Externí odkaz:
https://doaj.org/article/1cdc0312eb1144faa9fac2eabcb27d5b
Autor:
Joshua Osuofa, Scott M. Husson
Publikováno v:
Membranes, Vol 13, Iss 5, p 511 (2023)
Protein A chromatography is ubiquitous to antibody purification. The high specificity of Protein A for binding the Fc-region of antibodies and related products enables unmatched clearance of process impurities like host cell proteins, DNA, and virus
Externí odkaz:
https://doaj.org/article/ad4b5a86ac4945c087328414a4545087
Publikováno v:
Journal of chromatography. A. 1689
We developed a computational framework that integrates commercial software components to perform customizable technoeconomic feasibility analyses. The use of multiple software packages overcomes the shortcomings of each to provide a detailed simulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a38a284a56ff7945e21077847367207
https://pubmed.ncbi.nlm.nih.gov/36586284
https://pubmed.ncbi.nlm.nih.gov/36586284
Publikováno v:
Biotechnology progressREFERENCES. 37(3)
This contribution reports on a study using Purexa™-MQ multimodal anion-exchange (AEX) membranes for protein polishing at elevated solution conductivities. Dynamic binding capacities (DBC10 ) of bovine serum albumin (BSA), human immunoglobulins, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::211bc01cf0b28041ed8d31aa0241b059
https://pubmed.ncbi.nlm.nih.gov/33475239
https://pubmed.ncbi.nlm.nih.gov/33475239