Výsledky vyhledávání - "Joshua O. Ocheje"

Dietary stigmastane-type saponins as promising dual-target directed inhibitors of SARS-CoV-2 proteases: a structure-based screening

Autor: Oludare M. Ogunyemi, Charles O. Olaiya, Joseph O. Adebayo, Ibrahim M. Ibrahim, Modupe M. Fabusiwa, Joshua O. Ocheje, Gideon A. Gyebi

Publikováno v: RSC advances. 11(53)

Despite the development of COVID-19 vaccines, at present, there is still no approved antiviral drug against the pandemic. The SARS-CoV-2 3-chymotrypsin-like proteases (S-3CLpro) and papain-like protease (S-PLpro) are essential for the viral prolifera

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78e643afed2daa2913629f18d77de163
https://pubmed.ncbi.nlm.nih.gov/35497510

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Structure-based virtual screening suggests inhibitors of 3-Chymotrypsin-Like Protease of SARS-CoV-2 from Vernonia amygdalina and Occinum gratissimum

Autor: Modupe M. Fabusiwa, Oludare M. Ogunyemi, Adegbenro P. Adegunloye, Charles O. Olaiya, Gideon A. Gyebi, Abdo A. Elfiky, Joseph O. Adebayo, Ibrahim M. Ibrahim, Joshua O. Ocheje

Publikováno v: Computers in Biology and Medicine

Antiviral culinary plants are potential bioresources for preventive nutraceuticals and/or antiviral drugs in COVID-19. Structure-based virtual screening was undertaken to screen 173 compounds previously reported from Vernonia amygdalina and Occinum g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3ef74e29db3bcf003529efb8657ca28
https://doi.org/10.21203/rs.3.rs-301445/v1

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