Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Joshua O Sestak"'
Autor:
Joshua O Sestak, Bradley P Sullivan, Sharadvi Thati, Laura Northrup, Brittany Hartwell, Lorena Antunez, M Laird Forrest, Charlotte M Vines, Teruna J Siahaan, Cory Berkland
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 1, Iss C (2014)
Autoimmune diseases such as multiple sclerosis (MS) are typified by the misrecognition of self-antigen and the clonal expansion of autoreactive T cells. Antigen-specific immunotherapies (antigen-SITs) have long been explored as a means to desensitize
Externí odkaz:
https://doaj.org/article/8ab9ff58c3e740d79df828ab13b98770
Autor:
Rebuma Firdessa-Fite, Stephanie N. Johnson, Camillo Bechi Genzano, Martin A. Leon, Amy Ku, Fernando A. Ocampo Gonzalez, Joshua D. Milner, Joshua O. Sestak, Cory Berkland, Remi J. Creusot
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Autoantigen-specific immunotherapy using peptides offers a more targeted approach to treat autoimmune diseases, but clinical implementation has been challenging. We previously showed that multivalent delivery of peptides as soluble antigen arrays (SA
Externí odkaz:
https://doaj.org/article/49beca032d1f4ac2a42d36f7cf922cc6
Autor:
Rebuma Firdessa-Fite, Stephanie N. Johnson, Martin A. Leon, Joshua O. Sestak, Cory Berkland, Remi J. Creusot
Publikováno v:
bioRxiv
Autoantigen-specific immunotherapy using peptides offers a more targeted approach to treat autoimmune diseases, but the limitedin vivostability and uptake of peptides impedes clinical implementation. We previously showed that multivalent delivery of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64d645f2198aa6e010e1d1e99998b025
https://europepmc.org/articles/PMC10187310/
https://europepmc.org/articles/PMC10187310/
Autor:
Rebuma Firdessa-Fite, Cory Berkland, Remi J. Creusot, Joshua O Sestak, Chad J. Pickens, Martin A. Leon, Justin K Ruffalo
Publikováno v:
ACS Chem Biol
Type 1 diabetes (T1D) is an autoimmune disorder which develops when insulin-producing, pancreatic beta cells are destroyed by an aberrant immune response. Current therapies for T1D either treat symptoms or cause global immunosuppression, which leave
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b73d064224c9207b85f0c6d3889d0e73
https://doi.org/10.1021/acschembio.9b00090
https://doi.org/10.1021/acschembio.9b00090
Autor:
John C. Cambier, Martin A. Leon, Cory Berkland, Scott Wemlinger, C. Russell Middaugh, Joshua O Sestak, Justin K Ruffalo, Nicholas R. Larson
Publikováno v:
Mol Pharm
Autoimmune diseases are believed to be highly dependent on loss of immune tolerance to self-antigens. Currently, no treatments have been successful clinically in inducing autoantigen-specific tolerance, including efforts to utilize antigen-specific i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bc8c221c63fe8deb4fe9c281add8e7a
https://doi.org/10.1021/acs.molpharmaceut.8b01250
https://doi.org/10.1021/acs.molpharmaceut.8b01250