Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Joshua N. Douglas"'
Autor:
Lindsay Meyers, Joshua N. Douglas, Lidia A. Gardner, Yoojin Shin, Michael C. Levin, Sangmin Lee
Publikováno v:
Degenerative Neurological and Neuromuscular Disease
Multiple sclerosis (MS) is a complex autoimmune disease that impairs the central nervous system (CNS). The neurological disability and clinical course of the disease is highly variable and unpredictable from one patient to another. The cause of MS is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6a43d9deb9e7450b99005938c36c4b1
http://europepmc.org/articles/PMC7337253
http://europepmc.org/articles/PMC7337253
Autor:
Lidia A. Gardner, Sangmin Lee, Joshua N. Douglas, Hannah E. Salapa, Michael C. Levin, Yoojin Shin
Publikováno v:
Journal of neuroimmunology. 304
Several years following its discovery in 1980, infection with human T-lymphotropic virus type 1 (HTLV-1) was shown to cause HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP), a disease biologically similar to progressive forms of mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d8832e453d7fb127b4247573e380138
https://pubmed.ncbi.nlm.nih.gov/27449854
https://pubmed.ncbi.nlm.nih.gov/27449854
Autor:
Lidia A. Gardner, Hannah E. Salapa, Michael C. Levin, Benjamin M. Segal, Paul E. Sawchenko, Sangmin Lee, Joshua N. Douglas, Stephen J. Lalor
Publikováno v:
Journal of Neuroinflammation
Background Neurodegeneration is believed to be the primary cause of permanent, long-term disability in patients with multiple sclerosis. The cause of neurodegeneration in multiple sclerosis appears to be multifactorial. One mechanism that has been im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61922bf823e0041c97b71991a332e923
https://pubmed.ncbi.nlm.nih.gov/27391474
https://pubmed.ncbi.nlm.nih.gov/27391474
Autor:
Joshua N. Douglas, Lidia A. Gardner, Chassidy J. Groover, David D. Brand, Sangmin Lee, Lindsay Meyers, Michael C. Levin
Publikováno v:
Journal of neuroimmunology. 277(1-2)
Apolipoprotein A1 (Apo A-I), the most abundant component of high-density lipoprotein (HDL), is an anti-inflammatory molecule, yet its potential role in the pathogenesis of multiple sclerosis (MS) has not been fully investigated. In this study, Wester
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e752287bdc89bb1648d18688620d4663
https://pubmed.ncbi.nlm.nih.gov/25468275
https://pubmed.ncbi.nlm.nih.gov/25468275
Autor:
Joshua N. Douglas, Michael C. Levin, Chelsea Cooper, Lidia A. Gardner, Yoojin Shin, Sangmin Lee
Publikováno v:
Journal of Clinical & Cellular Immunology.
For years, investigators have sought to prove that myelin antigens are the primary targets of autoimmunity in multiple sclerosis (MS). Recent experiments have begun to challenge this assumption, particularly when studying the neurodegenerative phase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13afc8c424ed68a5046dcf7c3c7c2506
https://doi.org/10.4172/2155-9899.1000148
https://doi.org/10.4172/2155-9899.1000148
Autor:
Lidia A. Gardner, Chassidy J. Groover, Michael C. Levin, Joshua N. Douglas, Yoojin Shin, Sangmin Lee
Publikováno v:
Journal of visualized experiments : JoVE. (67)
Antibodies provide the ability to gain novel insight into various events taking place in living systems. The ability to produce highly specific antibodies to target proteins has allowed for very precise biological questions to be addressed. Important
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::000576e1c25a5caa80b409a7330911d9
https://pubmed.ncbi.nlm.nih.gov/23051967
https://pubmed.ncbi.nlm.nih.gov/23051967
Autor:
Michael C. Levin, Chassidy J. Groover, Yoojin Shin, Sangmin Lee, Lidia A. Gardner, Joshua N. Douglas
Publikováno v:
Journal of Visualized Experiments.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8a902d97d1e5285045b78aee39b1a2c
https://doi.org/10.3791/4154-v
https://doi.org/10.3791/4154-v
Autor:
Chassidy J. Groover, Sangmin Lee, Joshua N. Douglas, Lidia A. Gardner, Yoojin Shin, Michael C. Levin
Publikováno v:
Degenerative Neurological and Neuromuscular Disease. :175
Considering there are no treatments for progressive forms of multiple sclerosis (MS), a comprehensive understanding of the role of neurodegeneration in the pathogenesis of MS should lead to novel therapeutic strategies to treat it. Many studies have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::915d21c82a95c32d25846fcf1d07ece9
https://doi.org/10.2147/dnnd.s38353
https://doi.org/10.2147/dnnd.s38353
Autor:
Joshua N. Douglas, Sangmin Lee, Chassidy Groover, Cedric S. Raine, Michael C. Levin, Lidia A. Gardner, Yoojin Shin
Publikováno v:
Neurology. 78:P07.087-P07.087
Objective: To test whether antibodies to heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) in multiple sclerosis (MS) patients might contribute to alterations in neuronal function using in vitro and in vivo models of pathogenesis. Background MS p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62d597da670866dd4b8c2ef9c304dc17
https://doi.org/10.1212/wnl.78.1_meetingabstracts.p07.087
https://doi.org/10.1212/wnl.78.1_meetingabstracts.p07.087