Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Joshua Mayoral"'
Autor:
Joshua Mayoral, Rebekah B. Guevara, Yolanda Rivera-Cuevas, Vincent Tu, Tadakimi Tomita, Julia D. Romano, Leslie Gunther-Cummins, Simone Sidoli, Isabelle Coppens, Vernon B. Carruthers, Louis M. Weiss
Publikováno v:
mBio, Vol 13, Iss 4 (2022)
ABSTRACT The intracellular parasite Toxoplasma gondii adapts to diverse host cell environments within a replicative compartment that is heavily decorated by secreted proteins. In an attempt to identify novel parasite secreted proteins that influence
Externí odkaz:
https://doaj.org/article/a0a4d9258960439ea8a171b1b9cb0df0
Autor:
Yolanda Rivera-Cuevas, Joshua Mayoral, Manlio Di Cristina, Anna-Lisa E Lawrence, Einar B Olafsson, Romir K Patel, Dishari Thornhill, Benjamin S Waldman, Akira Ono, Jonathan Z Sexton, Sebastian Lourido, Louis M Weiss, Vern B Carruthers
Publikováno v:
PLoS Pathogens, Vol 17, Iss 12, p e1010138 (2021)
Toxoplasma gondii is a master manipulator capable of effectively siphoning the resources from the host cell for its intracellular subsistence. However, the molecular underpinnings of how the parasite gains resources from its host remain largely unkno
Externí odkaz:
https://doaj.org/article/cd8bd035ddc44eb6a2451e248389231b
Autor:
Tadakimi Tomita, Debanjan Mukhopadhyay, Bing Han, Rama Yakubu, Vincent Tu, Joshua Mayoral, Tatsuki Sugi, Yanfen Ma, Jeroen P. J. Saeij, Louis M. Weiss
Publikováno v:
mBio, Vol 12, Iss 3 (2021)
Toxoplasma gondii
Externí odkaz:
https://doaj.org/article/ff10a6f7fd3a48008a8a7b197411a3c2
Autor:
Joshua Mayoral, Tadakimi Tomita, Vincent Tu, Jennifer T Aguilan, Simone Sidoli, Louis M Weiss
Publikováno v:
PLoS Pathogens, Vol 16, Iss 12, p e1008771 (2020)
The intracellular parasite Toxoplasma gondii infects a large proportion of humans worldwide and can cause adverse complications in the settings of immune-compromise and pregnancy. T. gondii thrives within many different cell types due in part to its
Externí odkaz:
https://doaj.org/article/61275b6a34194c4c9aae976395d8f55a
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
ABSTRACT The ubiquitous parasite Toxoplasma gondii exhibits an impressive ability to maintain chronic infection of its host for prolonged periods. Despite this, little is known regarding whether and how T. gondii bradyzoites, a quasi-dormant life sta
Externí odkaz:
https://doaj.org/article/56e96906766f447597a5e1554c3a5c9a
Autor:
Vincent Tu, Joshua Mayoral, Rama R. Yakubu, Tadakimi Tomita, Tatsuki Sugi, Bing Han, Tere Williams, Yanfen Ma, Louis M. Weiss
Publikováno v:
mSphere, Vol 5, Iss 1 (2020)
ABSTRACT Toxoplasma gondii causes a chronic infection that affects a significant portion of the world’s population, and this latent infection is the source of reactivation of toxoplasmosis. An attribute of the slowly growing bradyzoite stage of the
Externí odkaz:
https://doaj.org/article/6176377d4b5445eca9735feae7daec95
Autor:
Vincent Tu, Tadakimi Tomita, Tatsuki Sugi, Joshua Mayoral, Bing Han, Rama R. Yakubu, Tere Williams, Aline Horta, Yanfen Ma, Louis M. Weiss
Publikováno v:
mBio, Vol 11, Iss 1 (2020)
ABSTRACT A characteristic of the latent cyst stage of Toxoplasma gondii is a thick cyst wall that forms underneath the membrane of the bradyzoite vacuole. Previously, our laboratory group published a proteomic analysis of purified in vitro cyst wall
Externí odkaz:
https://doaj.org/article/b43032832a134d59b1e6e87953ef94d2
Autor:
Bing Han, Yanfen Ma, Vincent Tu, Tadakimi Tomita, Joshua Mayoral, Tere Williams, Aline Horta, Huan Huang, Louis M. Weiss
Publikováno v:
mBio, Vol 10, Iss 4 (2019)
ABSTRACT Microsporidia are opportunistic intracellular pathogens that can infect a wide variety of hosts ranging from invertebrates to vertebrates. During invasion, the microsporidian polar tube pushes into the host cell, creating a protective microe
Externí odkaz:
https://doaj.org/article/1bbf7c69a50c49da9e145fe3b93907f2
Autor:
Vincent Tu, Joshua Mayoral, Tatsuki Sugi, Tadakimi Tomita, Bing Han, Yan Fen Ma, Louis M. Weiss
Publikováno v:
mBio, Vol 10, Iss 2 (2019)
ABSTRACT The tissue cyst of Toxoplasma gondii, found in latent infection, serves a critical role in both transmission and reactivation of this organism. Within infected cells, slowly replicating parasites (bradyzoites) are surrounded by a cyst matrix
Externí odkaz:
https://doaj.org/article/0fef660c2a504f80bd83788c140ad2ec
Autor:
Julia D. Romano, Joshua Mayoral, Rebekah B. Guevara, Yolanda Rivera-Cuevas, Vern B. Carruthers, Louis M. Weiss, Isabelle Coppens
Publikováno v:
Journal of Cell Science. 136
Intracellular pathogens exploit cellular resources through host cell manipulation. Within its nonfusogenic parasitophorous vacuole (PV), Toxoplasma gondii targets host nutrient-filled organelles and sequesters them into the PV through deep invaginati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d3a394893578f549a3374ac79563f22
https://doi.org/10.1242/jcs.260159
https://doi.org/10.1242/jcs.260159