Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Joshua M. Zent"'
Autor:
Priya H. Dedhia, Hemamylammal Sivakumar, Marco A. Rodriguez, Kylie G. Nairon, Joshua M. Zent, Xuguang Zheng, Katie Jones, Liudmila V. Popova, Jennifer L. Leight, Aleksander Skardal
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Adrenocortical carcinoma (ACC) has a poor prognosis, and no new drugs have been identified in decades. The absence of drug development can partly be attributed to a lack of preclinical models. Both animal models and 2D cell cultures of ACC f
Externí odkaz:
https://doaj.org/article/b1b85de5b9c44c18b6df603e0e5919b5
Publikováno v:
iScience, Vol 25, Iss 7, Pp 104645- (2022)
Summary: Primary tumors secrete large quantities of cytokines and exosomes into the bloodstream, which are uptaken at downstream sites and induce a pro-fibrotic, pro-inflammatory premetastatic niche. Niche development is associated with later increas
Externí odkaz:
https://doaj.org/article/241cba1c022542f79a57b16e333d0223
Tumor cell-conditioned media drives collagen remodeling via fibroblast and pericyte activation in an
Publikováno v:
iScience. 25(7)
Primary tumors secrete large quantities of cytokines and exosomes into the bloodstream, which are uptaken at downstream sites and induce a pro-fibrotic, pro-inflammatory premetastatic niche. Niche development is associated with later increased metast
Autor:
Caitlin E Jones, Joe T Sharick, Sheila E Colbert, Vasudha C Shukla, Joshua M Zent, Michael C Ostrowski, Samir N Ghadiali, Steven T Sizemore, Jennifer L Leight
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0245653 (2021)
Collagen deposition contributes to both high mammographic density and breast cancer progression. Low stromal PTEN expression has been observed in as many as half of breast tumors and is associated with increases in collagen deposition, however the me
Externí odkaz:
https://doaj.org/article/9f9da990094543c491980f3fcf8a6c82