Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Joshua M. Uronis"'
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Patients with oral cavity squamous cell carcinoma (OCSCC) are predominantly human papillomavirus (HPV)(−), and treatment typically involves surgical resection ± neck dissection, followed by radiation ± chemotherapy. We previously described four m
Externí odkaz:
https://doaj.org/article/33bf6ffca9d14ee49feb01a110ac7a53
Autor:
Joel R. Eisner, Kirk D. Beebe, Gregory M. Mayhew, Yoichiro Shibata, Yuelong Guo, Carol Farhangfar, Farhang Farhangfar, Joshua M. Uronis, Jill Mooney, Michael V. Milburn, David Foureau, Richard L. White, Asim Amin, Marcos E. Milla
Publikováno v:
Cancer Research Communications. 2:894-903
Recombinant human high-dose IL2 (HD-IL2; aldesleukin) was one of the first approved immune-oncology agents based upon clinical activity in renal cell carcinoma (RCC) and metastatic melanoma but use was limited due to severe toxicity. Next-generation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3af86004040503294c91ba86fa069a5e
https://doi.org/10.1158/2767-9764.crc-21-0153
https://doi.org/10.1158/2767-9764.crc-21-0153
Autor:
Joel R. Eisner, Gregory M. Mayhew, James M. Davison, Kirk D. Beebe, Yoichiro Shibata, Yuelong Guo, Carol Farhangfar, Farhang Farhangfar, Joshua M. Uronis, Jeffrey M. Conroy, Michael V. Milburn, David Neil. Hayes, Kathryn F. Mileham
Publikováno v:
Clinical Cancer Research.
Purpose: The Piedmont study is a prospectively designed retrospective evaluation of a new 48-gene antifolate response signature (AF-PRS) in patients with locally advanced/metastatic NS-NSCLC treated with pemetrexed-containing platinum doublet chemoth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43c4953b0bb03f5b73d0ac32e56d115c
https://doi.org/10.1158/1078-0432.ccr-22-2558
https://doi.org/10.1158/1078-0432.ccr-22-2558
Autor:
Marcos E. Milla, Asim Amin, Richard L. White, David Foureau, Michael V. Milburn, Jill Mooney, Joshua M. Uronis, Farhang Farhangfar, Carol Farhangfar, Yuelong Guo, Yoichiro Shibata, Gregory M. Mayhew, Kirk D. Beebe, Joel R. Eisner
Recombinant human high-dose IL2 (HD-IL2; aldesleukin) was one of the first approved immune-oncology agents based upon clinical activity in renal cell carcinoma (RCC) and metastatic melanoma but use was limited due to severe toxicity. Next-generation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aee2f498634f181e0903dde0904d827
https://doi.org/10.1158/2767-9764.c.6550872.v1
https://doi.org/10.1158/2767-9764.c.6550872.v1
Autor:
Marcos E. Milla, Asim Amin, Richard L. White, David Foureau, Michael V. Milburn, Jill Mooney, Joshua M. Uronis, Farhang Farhangfar, Carol Farhangfar, Yuelong Guo, Yoichiro Shibata, Gregory M. Mayhew, Kirk D. Beebe, Joel R. Eisner
this is a test
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dcd889514c515c62aa335b1a1f130c0
https://doi.org/10.1158/2767-9764.22545183
https://doi.org/10.1158/2767-9764.22545183
Autor:
Marcos E. Milla, Asim Amin, Richard L. White, David Foureau, Michael V. Milburn, Jill Mooney, Joshua M. Uronis, Farhang Farhangfar, Carol Farhangfar, Yuelong Guo, Yoichiro Shibata, Gregory M. Mayhew, Kirk D. Beebe, Joel R. Eisner
40 gene IL-2 response classifier and related immune cell types
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e912be1d5a6174fc4d7074ca2edfe78
https://doi.org/10.1158/2767-9764.22545180
https://doi.org/10.1158/2767-9764.22545180
Autor:
Patrick Eulitt, William Weir, Michele C. Hayward, Tracy L. Rose, Matthew I. Milowsky, Katrina A. McGinty, Michael V. Millburn, Mi Zhou, Yoichiro Shibata, Matthew E. Nielsen, Ashley H. Salazar, Gregory Mayhew, William Y. Kim, Joel R. Eisner, Angela B. Smith, Sara E. Wobker, Joshua M. Uronis, Michael Woods
Publikováno v:
Br J Cancer
Background FGFR3-altered urothelial cancer (UC) correlates with a non-T cell-inflamed phenotype and has therefore been postulated to be less responsive to immune checkpoint blockade (ICB). Preclinical work suggests FGFR3 signalling may suppress pathw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a067ed93f6f1a9fec850b6412c6c901
https://europepmc.org/articles/PMC8548561/
https://europepmc.org/articles/PMC8548561/
Autor:
Kirk Beebe, Joel Robert Eisner, Yoichiro Shibata, James M Davison, John Guo, Carol J. Farhangfar, Farhang Farhangfar, Joshua M. Uronis, Jill Mooney, Michael Vance Milburn, David Foureau, Richard L. White, Asim Amin, Marcos E Milla
Publikováno v:
Journal of Clinical Oncology. 40:e16501-e16501
e16501 Background: High-dose interleukin-2 (HD IL-2) was the first approved immune-oncology (IO) agent based on proven clinical efficacy in renal cell carcinoma (RCC) and metastatic melanoma, but its use was limited due to significant toxicities. Mul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94c31c7cb7026b1e1eb92611aaee04b8
https://doi.org/10.1200/jco.2022.40.16_suppl.e16501
https://doi.org/10.1200/jco.2022.40.16_suppl.e16501
Autor:
Tracy L. Rose, William H. Weir, Gregory M. Mayhew, Yoichiro Shibata, Patrick Eulitt, Joshua M. Uronis, Mi Zhou, Matthew Nielsen, Angela B. Smith, Michael Woods, Michele C. Hayward, Ashley H. Salazar, Matthew I. Milowsky, Sara E. Wobker, Katrina McGinty, Michael V. Millburn, Joel R. Eisner, William Y. Kim
Publikováno v:
British Journal of Cancer. 126:1237-1237
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96a18f3be50748b01cf0b45d80ab500e
https://doi.org/10.1038/s41416-022-01781-y
https://doi.org/10.1038/s41416-022-01781-y
Autor:
Joshua M Uronis, Takuya Osada, Shannon McCall, Xiao Yi Yang, Christopher Mantyh, Michael A Morse, H Kim Lyerly, Bryan M Clary, David S Hsu
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38422 (2012)
Mouse models have been developed to investigate colorectal cancer etiology and evaluate new anti-cancer therapies. While genetically engineered and carcinogen-induced mouse models have provided important information with regard to the mechanisms unde
Externí odkaz:
https://doaj.org/article/31ccba9d32894b688029c6755798c673