Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Joshua M. Svendsen"'
Autor:
Joshua M. Svendsen, Kailee J. Reed, Tarah Vijayasarathy, Brooke E. Montgomery, Rachel M. Tucci, Kristen C. Brown, Taylor N. Marks, Dieu An H. Nguyen, Carolyn M. Phillips, Taiowa A. Montgomery
Publikováno v:
Cell Reports, Vol 29, Iss 10, Pp 3187-3199.e4 (2019)
Summary: The germline contains an immortal cell lineage that ensures the faithful transmission of genetic and, in some instances, epigenetic information from one generation to the next. Here, we show that in Caenorhabditis elegans, the small RNA 3′
Externí odkaz:
https://doaj.org/article/52c76bb55d9e4a2d81b96f52874d7dce
Autor:
Daniel B. Sloan, Jessica M. Warren, Thalia Salinas-Giegé, Joshua M. Svendsen, Laurence Maréchal-Drouard, Nicole L. Coots, Guillaume Hummel, Kristen C. Brown
Publikováno v:
RNA Biol
RNA Biology
RNA Biology, Taylor & Francis, 2020, pp.1-15. ⟨10.1080/15476286.2020.1792089⟩
RNA Biology
RNA Biology, Taylor & Francis, 2020, pp.1-15. ⟨10.1080/15476286.2020.1792089⟩
Differences in tRNA expression have been implicated in a remarkable number of biological processes. There is growing evidence that tRNA genes can play dramatically different roles depending on both expression and post-transcriptional modification, ye
Autor:
Taiowa A. Montgomery, Joshua M. Svendsen, Erin Osborne Nishimura, Dustin L. Updike, Tarah Vijayasarathy, Taylor N Marks, Kailee J. Reed, Brooke E Montgomery, Dylan M. Parker, Kristen C. Brown
Publikováno v:
Nucleic Acids Research
Piwi-interacting RNAs (piRNAs) and small interfering RNAs (siRNAs) are distinct classes of small RNAs required for proper germline development. To identify the roles of piRNAs and siRNAs in regulating gene expression in Caenorhabditis elegans, we sub
Mitochondrial mutations in Caenorhabditis elegans show signatures of oxidative damage and an AT-bias
Publikováno v:
Genetics
Rapid mutation rates are typical of mitochondrial genomes (mtDNAs) in animals, but it is not clear why. The difficulty of obtaining measurements of mtDNA mutation that are not biased by natural selection has stymied efforts to distinguish between com
Autor:
Brooke E Montgomery, Taiowa A. Montgomery, Joshua M. Svendsen, Kristen C. Brown, Rachel M. Tucci
Publikováno v:
Nucleic Acids Research
Caenorhabditis elegans contains 25 Argonautes, of which, ALG-1 and ALG-2 are known to primarily interact with miRNAs. ALG-5 belongs to the AGO subfamily of Argonautes that includes ALG-1 and ALG-2, but its role in small RNA pathways is unknown. We an
Autor:
Taylor N Marks, Kailee J. Reed, Brooke E Montgomery, Tarah Vijayasarathy, Dieu An H. Nguyen, Rachel M. Tucci, Carolyn M. Phillips, Kristen C. Brown, Taiowa A. Montgomery, Joshua M. Svendsen
Publikováno v:
Cell reports
Cell Reports, Vol 29, Iss 10, Pp 3187-3199.e4 (2019)
Cell Reports, Vol 29, Iss 10, Pp 3187-3199.e4 (2019)
SUMMARY The germline contains an immortal cell lineage that ensures the faithful transmission of genetic and, in some instances, epigenetic information from one generation to the next. Here, we show that in Caenorhabditis elegans, the small RNA 3′-
Autor:
Joshua M. Svendsen, Thomas E. Bickett, Agnieszka Rynda-Apple, Joshua M. Klonoski, Trevor Watson, Alexandra Britt, Victor C. Huber, Jeff T. Nelson, Tonia J. Gau, Evelyn H. Schlenker, Michael S. Chaussee
Publikováno v:
Viral immunology. 31(6)
Influenza virus infections can be complicated by bacterial superinfections, which are medically relevant because of a complex interaction between the host, the virus, and the bacteria. Studies to date have implicated several influenza virus genes, va
Autor:
Joshua M. Svendsen, Thomas E. Bickett, Thomas A. Penfound, Victor C. Huber, Michael S. Chaussee, Margaret J. Schuneman, Joshua M. Klonoski, Brian A. Juber, Brandon Burum, James B. Dale, Grigoriy Sereda, Heather R. Hurtig
Publikováno v:
Vaccine. 32:5241-5249
Influenza virus infections are associated with a significant number of illnesses and deaths on an annual basis. Many of the deaths are due to complications from secondary bacterial invaders, including Streptococcus pneumoniae, Staphylococcus aureus,
Publikováno v:
Developmental Cell. 44:657-658
piRNAs are known to silence transposable elements, but not all piRNAs match transposon sequences. Recent studies from Shen et al. (2018) and Zhang et al. (2018) identify rules for piRNA target recognition in Caenorhabditis elegans. Permissive pairing
Autor:
Warren, Jessica M., Salinas-Giegé, Thalia, Hummel, Guillaume, Coots, Nicole L., Svendsen, Joshua M., Brown, Kristen C., Drouard, Laurence, Sloan, Daniel B.
Publikováno v:
RNA Biology; Jan2021, Vol. 18 Issue 1, p64-78, 15p