Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Joshua M. Stewart"'
Autor:
Maigan A. Brusko, Joshua M. Stewart, Amanda L. Posgai, Clive H. Wasserfall, Mark A. Atkinson, Todd M. Brusko, Benjamin G. Keselowsky
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Current monotherapeutic agents fail to restore tolerance to self-antigens in autoimmune individuals without systemic immunosuppression. We hypothesized that a combinatorial drug formulation delivered by a poly-lactic-co-glycolic acid (PLGA) dual-size
Externí odkaz:
https://doaj.org/article/4ff9246955944b4f829c915a28e9f32d
Autor:
William Douglas Woody, Joshua M. Stewart, Krista D. Forrest, Lourdes Janet Camacho, Skye A. Woestehoff, Karlee R. Provenza, Alexis T. Walker, Steven J. Powner
Publikováno v:
Cogent Psychology, Vol 5, Iss 1 (2018)
Triers of fact evaluated trial materials involving disputed confessions, false-evidence ploys (FEPs) during interrogation, and expert testimony. In two experiments, we assessed pre-deliberation and post-deliberation trial decisions as well as individ
Externí odkaz:
https://doaj.org/article/309d82f314fc49cb8557318b308e78e1
Autor:
Alexander J. Kwiatkowski, Eric Y. Helm, Joshua M. Stewart, Theodore T. Drashansky, Jonathan J. Cho, Dorina Avram, Benjamin G. Keselowsky
Antigen-specific therapies hold promise for treating autoimmune diseases such as multiple sclerosis while avoiding the deleterious side effects of systemic immune suppression. In this study, an antigen-specific dual-sized microparticle (dMP) immunoth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c874970325e86cd8d418991cc631911
https://doi.org/10.1101/2022.03.25.485841
https://doi.org/10.1101/2022.03.25.485841
Autor:
Benjamin G. Keselowsky, Natalia V. Dolgova, Todd M. Brusko, Chang-Qing Xia, Mark A. Atkinson, Michael J. Clare-Salzler, Matthew R. Carstens, Gregory P Marshall, Clive Wasserfall, Ying Zhang, Joshua M. Stewart, Jamal S. Lewis
Publikováno v:
ACS biomaterials science & engineering, vol 5, iss 5
[Image: see text] Antigen specificity is a primary goal in developing curative therapies for autoimmune disease. Dendritic cells (DCs), as the most effective antigen presenting cells in the body, represent a key target to mediate restoration of antig
Publikováno v:
ACS Biomater Sci Eng
Type 1 diabetes (T1D) pathophysiology, while incompletely understood, has in part been attributed to aberrant presentation of self-antigen plus proinflammatory co-stimulation by professional antigen-presenting cells (APCs). Therapies targeting dendri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1193a0e9db598258e92ad39212f7f9f9
https://europepmc.org/articles/PMC8108782/
https://europepmc.org/articles/PMC8108782/
Publikováno v:
Nat Rev Mater
A cure for type 1 diabetes (T1D) would help millions of people worldwide but remains elusive to date. Tolerogenic vaccines and β-cell replacement therapy are complementary therapies that seek to address aberrant T1D autoimmune attack and subsequent
Publikováno v:
Behavioral Sciences & the Law. 36:12-31
We assessed experimental false confession studies using a meta-analysis to evaluate the prevalence of false confessions across methodologies and several moderator variables. False confessions were more likely in typing task studies than in collaborat
Autor:
Joshua M. Stewart, Benjamin G. Keselowsky, Jonathan J. Cho, Alexander J. Kwiatkowski, Dorina Avram
Publikováno v:
Adv Healthc Mater
Autoimmune diseases affect 10% of the world’s population, and 1 in 200 people worldwide suffer from either multiple sclerosis (MS) or type 1 diabetes (T1D). While the targeted organ systems are different, MS and T1D share similarities in terms of a
Immunotherapy has been widely explored for applications to both augment and suppress intrinsic host immunity. Clinical achievements have seen a number of immunotherapeutic drugs displace established strategies like chemotherapy in treating immune-ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b77eea5f617ff74eec08ad1fb58e1ec
https://europepmc.org/articles/PMC5663321/
https://europepmc.org/articles/PMC5663321/
Autor:
Ashley N. Zuniga, Benjamin G. Keselowsky, Joshua M. Stewart, Jonathan J. Cho, Kyle J. Lorentsen, Theodore T. Drashansky, Maigan A. Brusko, Dorina Avram
Publikováno v:
Biomaterials. 143
Antigen-specific treatments are highly desirable for autoimmune diseases in contrast to treatments which induce systemic immunosuppression. A novel antigen-specific therapy has been developed which, when administered semi-therapeutically, is highly e