Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Joshua M. Stark"'
Autor:
Tuerdi Subati, Zhenjiang Yang, Matthew B. Murphy, Joshua M. Stark, David Z. Trykall, Sean S. Davies, Joey V. Barnett, Katherine T. Murray
Publikováno v:
Cells, Vol 13, Iss 6, p 483 (2024)
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, yet the cellular and molecular mechanisms underlying the AF substrate remain unclear. Isolevuglandins (IsoLGs) are highly reactive lipid dicarbonyl products that mediate oxidat
Externí odkaz:
https://doaj.org/article/513c4d95dd3a462faa2c4beeed8678c4
Autor:
Dan M. Roden, Prince J. Kannankeril, Annet Kirabo, Joshua M. Stark, Joseph C Van Amburg, Joey V. Barnett, Ashley Pitzer, Tuerdi Subati, Zhenjiang Yang, Isis L Christopher, Charles D Smart, Matthew B Murphy, Katherine T. Murray, Meena S. Madhur
Publikováno v:
Circulation. 142
Introduction: Inflammation and oxidative stress are linked to multiple risk factors for atrial fibrillation (AF), and to AF itself in the setting of sterile injury (e.g. after catheter ablation or cardiac surgery). However, anti-inflammatory therapie
Autor:
Sean S. Davies, Prince J. Kannankeril, Joshua M. Stark, James M. Luther, Annet Kirabo, Isis L Christopher, Meena S. Madhur, James B. Atkinson, Irene Zagol-Ikapitte, Liudmila V. Yermalitskaya, Scott R. Jafarian-Kerman, Matthew B Murphy, Agnes B. Fogo, David G. Harrison, Katherine T. Murray, Mohamed A. Saleh, Joey V. Barnett, Olivier Boutaud, Roxana Loperena, Joseph K. Prinsen, Venkataraman Amarnath, Tatiana N. Sidorova, Allison E. Norlander, Tuerdi Subati
Publikováno v:
JACC: Basic to Translational Science
Visual Abstract
Highlights • IsoLGs are highly reactive lipid dicarbonyl metabolites that constitute a major component of oxidative stress-related injury, and they promote the formation of amyloid. • In a hypertensive murine model, IsoLG add
Highlights • IsoLGs are highly reactive lipid dicarbonyl metabolites that constitute a major component of oxidative stress-related injury, and they promote the formation of amyloid. • In a hypertensive murine model, IsoLG add