Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Joshua M. Popp"'
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Differential allele-specific expression (ASE) is a powerful tool to study context-specific cis-regulation of gene expression. Such effects can reflect the interaction between genetic or epigenetic factors and a measured context or condition.
Externí odkaz:
https://doaj.org/article/ae58108479ce46709e24ba15486e4417
Autor:
Katherine Rhodes, Kenneth A Barr, Joshua M Popp, Benjamin J Strober, Alexis Battle, Yoav Gilad
Publikováno v:
eLife, Vol 11 (2022)
Practically all studies of gene expression in humans to date have been performed in a relatively small number of adult tissues. Gene regulation is highly dynamic and context-dependent. In order to better understand the connection between gene regulat
Externí odkaz:
https://doaj.org/article/28b87cc3cb934093b19eb1451ef1e52a
Autor:
Reem Elorbany, Joshua M Popp, Katherine Rhodes, Benjamin J Strober, Kenneth Barr, Guanghao Qi, Yoav Gilad, Alexis Battle
Publikováno v:
PLoS Genetics, Vol 18, Iss 1, p e1009666 (2022)
Dynamic and temporally specific gene regulatory changes may underlie unexplained genetic associations with complex disease. During a dynamic process such as cellular differentiation, the overall cell type composition of a tissue (or an in vitro cultu
Externí odkaz:
https://doaj.org/article/b050a2d543c34d2a9d933d5ab20fe484
Allele-specific expression, which measures the expression of two alleles of a gene in a diploid individual, is a powerful signal to study cis-regulatory effects. Comparing ASE across conditions, or differential ASE, can reveal context-specific gene r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5b1e49538d99e9c82165c03e9a591ca
https://doi.org/10.1101/2022.10.06.511215
https://doi.org/10.1101/2022.10.06.511215
