Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Joshua M. Lorenz-Guertin"'
Autor:
Joshua M. Lorenz-Guertin, Nadya Povysheva, Caitlyn A. Chapman, Matthew L. MacDonald, Marco Fazzari, Aparna Nigam, Jessica L. Nuwer, Sabyasachi Das, Megan L. Brady, Katarina Vajn, Matthew J. Bambino, Susan T. Weintraub, Jon W. Johnson, Tija C. Jacob
Publikováno v:
Neurobiology of Disease, Vol 185, Iss , Pp 106248- (2023)
Benzodiazepine (BZ) drugs treat seizures, anxiety, insomnia, and alcohol withdrawal by potentiating γ2 subunit containing GABA type A receptors (GABAARs). BZ clinical use is hampered by tolerance and withdrawal symptoms including heightened seizure
Externí odkaz:
https://doaj.org/article/ad34633e407d4057b7e50eb452454154
Autor:
Wilson Leung, Christopher D. Shaffer, Elizabeth J. Chen, Thomas J. Quisenberry, Kevin Ko, John M. Braverman, Thomas C. Giarla, Nathan T. Mortimer, Laura K. Reed, Sheryl T. Smith, Srebrenka Robic, Shannon R. McCartha, Danielle R. Perry, Lindsay M. Prescod, Zenyth A. Sheppard, Ken J. Saville, Allison McClish, Emily A. Morlock, Victoria R. Sochor, Brittney Stanton, Isaac C. Veysey-White, Dennis Revie, Luis A. Jimenez, Jennifer J. Palomino, Melissa D. Patao, Shane M. Patao, Edward T. Himelblau, Jaclyn D. Campbell, Alexandra L. Hertz, Maddison F. McEvilly, Allison R. Wagner, James Youngblom, Baljit Bedi, Jeffery Bettincourt, Erin Duso, Maiye Her, William Hilton, Samantha House, Masud Karimi, Kevin Kumimoto, Rebekah Lee, Darryl Lopez, George Odisho, Ricky Prasad, Holly Lyn Robbins, Tanveer Sandhu, Tracy Selfridge, Kara Tsukashima, Hani Yosif, Nighat P. Kokan, Latia Britt, Alycia Zoellner, Eric P. Spana, Ben T. Chlebina, Insun Chong, Harrison Friedman, Danny A. Mammo, Chun L. Ng, Vinayak S. Nikam, Nicholas U. Schwartz, Thomas Q. Xu, Martin G. Burg, Spencer M. Batten, Lindsay M. Corbeill, Erica Enoch, Jesse J. Ensign, Mary E. Franks, Breanna Haiker, Judith A. Ingles, Lyndsay D. Kirkland, Joshua M. Lorenz-Guertin, Jordan Matthews, Cody M. Mittig, Nicholaus Monsma, Katherine J. Olson, Guillermo Perez-Aragon, Alen Ramic, Jordan R. Ramirez, Christopher Scheiber, Patrick A. Schneider, Devon E. Schultz, Matthew Simon, Eric Spencer, Adam C. Wernette, Maxine E. Wykle, Elizabeth Zavala-Arellano, Mitchell J. McDonald, Kristine Ostby, Peter Wendland, Justin R. DiAngelo, Alexis M. Ceasrine, Amanda H. Cox, James E.B. Docherty, Robert M. Gingras, Stephanie M. Grieb, Michael J. Pavia, Casey L. Personius, Grzegorz L. Polak, Dale L. Beach, Heaven L. Cerritos, Edward A. Horansky, Karim A. Sharif, Ryan Moran, Susan Parrish, Kirsten Bickford, Jennifer Bland, Juliana Broussard, Kerry Campbell, Katelynn E. Deibel, Richard Forka, Monika C. Lemke, Marlee B. Nelson, Catherine O'Keeffe, S. Mariel Ramey, Luke Schmidt, Paola Villegas, Christopher J. Jones, Stephanie L. Christ, Sami Mamari, Adam S. Rinaldi, Ghazal Stity, Amy T. Hark, Mark Scheuerman, S. Catherine Silver Key, Briana D. McRae, Adam S. Haberman, Sam Asinof, Harriette Carrington, Kelly Drumm, Terrance Embry, Richard McGuire, Drew Miller-Foreman, Stella Rosen, Nadia Safa, Darrin Schultz, Matt Segal, Yakov Shevin, Petros Svoronos, Tam Vuong, Gary Skuse, Don W. Paetkau, Rachael K. Bridgman, Charlotte M. Brown, Alicia R. Carroll, Francesca M. Gifford, Julie Beth Gillespie, Susan E. Herman, Krystal L. Holtcamp, Misha A. Host, Gabrielle Hussey, Danielle M. Kramer, Joan Q. Lawrence, Madeline M. Martin, Ellen N. Niemiec, Ashleigh P. O'Reilly, Olivia A. Pahl, Guadalupe Quintana, Elizabeth A.S. Rettie, Torie L. Richardson, Arianne E. Rodriguez, Mona O. Rodriguez, Laura Schiraldi, Joanna J. Smith, Kelsey F. Sugrue, Lindsey J. Suriano, Kaitlyn E. Takach, Arielle M. Vasquez, Ximena Velez, Elizabeth J. Villafuerte, Laura T. Vives, Victoria R. Zellmer, Jeanette Hauke, Charles R. Hauser, Karolyn Barker, Laurie Cannon, Perouza Parsamian, Samantha Parsons, Zachariah Wichman, Christopher W. Bazinet, Diana E. Johnson, Abubakarr Bangura, Jordan A. Black, Victoria Chevee, Sarah A. Einsteen, Sarah K. Hilton, Max Kollmer, Rahul Nadendla, Joyce Stamm, Antoinette E. Fafara-Thompson, Amber M. Gygi, Emmy E. Ogawa, Matt Van Camp, Zuzana Kocsisova, Judith L. Leatherman, Cassie M. Modahl, Michael R. Rubin, Susana S. Apiz-Saab, Suzette M. Arias-Mejias, Carlos F. Carrion-Ortiz, Patricia N. Claudio-Vazquez, Debbie M. Espada-Green, Marium Feliciano-Camacho, Karina M. Gonzalez-Bonilla, Mariela Taboas-Arroyo, Dorianmarie Vargas-Franco, Raquel Montañez-Gonzalez, Joseph Perez-Otero, Myrielis Rivera-Burgos, Francisco J. Rivera-Rosario, Heather L. Eisler, Jackie Alexander, Samatha K. Begley, Deana Gabbard, Robert J. Allen, Wint Yan Aung, William D. Barshop, Amanda Boozalis, Vanessa P. Chu, Jeremy S. Davis, Ryan N. Duggal, Robert Franklin, Katherine Gavinski, Heran Gebreyesus, Henry Z. Gong, Rachel A. Greenstein, Averill D. Guo, Casey Hanson, Kaitlin E. Homa, Simon C. Hsu, Yi Huang, Lucy Huo, Sarah Jacobs, Sasha Jia, Kyle L. Jung, Sarah Wai-Chee Kong, Matthew R. Kroll, Brandon M. Lee, Paul F. Lee, Kevin M. Levine, Amy S. Li, Chengyu Liu, Max Mian Liu, Adam P. Lousararian, Peter B. Lowery, Allyson P. Mallya, Joseph E. Marcus, Patrick C. Ng, Hien P. Nguyen, Ruchik Patel, Hashini Precht, Suchita Rastogi, Jonathan M. Sarezky, Adam Schefkind, Michael B. Schultz, Delia Shen, Tara Skorupa, Nicholas C. Spies, Gabriel Stancu, Hiu Man Vivian Tsang, Alice L. Turski, Rohit Venkat, Leah E. Waldman, Kaidi Wang, Tracy Wang, Jeffrey W. Wei, Dennis Y. Wu, David D. Xiong, Jack Yu, Karen Zhou, Gerard P. McNeil, Robert W. Fernandez, Patrick Gomez Menzies, Tingting Gu, Jeremy Buhler, Elaine R. Mardis, Sarah C.R. Elgin
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 7, Iss 8, Pp 2439-2460 (2017)
The discordance between genome size and the complexity of eukaryotes can partly be attributed to differences in repeat density. The Muller F element (∼5.2 Mb) is the smallest chromosome in Drosophila melanogaster, but it is substantially larger (>1
Externí odkaz:
https://doaj.org/article/9273871cbe9a483c8152436abfdf7116
Autor:
Joshua M. Lorenz-Guertin, Matthew J. Bambino, Sabyasachi Das, Susan T. Weintraub, Tija C. Jacob
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Despite 50+ years of clinical use as anxiolytics, anti-convulsants, and sedative/hypnotic agents, the mechanisms underlying benzodiazepine (BZD) tolerance are poorly understood. BZDs potentiate the actions of gamma-aminobutyric acid (GABA), the prima
Externí odkaz:
https://doaj.org/article/5df4277df23c4691b7d8958bdc5354c4
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
GABA type A receptors (GABAARs) mediate the majority of fast inhibitory neurotransmission in the central nervous system (CNS). Most prevalent as heteropentamers composed of two α, two β, and a γ2 subunit, these ligand-gated ionotropic chloride cha
Externí odkaz:
https://doaj.org/article/a2a237770f3242b1851f415ebd39f3a2
Autor:
Wenzhong Wei, Sabyasachi Das, Qiming J. Wang, Huachen Huang, Jing Ye, Qian Xu, Adhiraj Roy, Dandan Sun, Bing Wang, Tija C. Jacob, Joshua M. Lorenz-Guertin
Publikováno v:
Molecular Neurobiology
Ca2+/calmodulin-dependent protein kinase II (CaMKII) has long been implicated in neuronal injury caused by acute ischemia/reperfusion (I/R). However, its precise role and regulatory mechanisms remain obscure. Here, we investigated the role of the CaM
Publikováno v:
Developmental Neurobiology. 78:238-270
Ubiquitous expression of GABA type A receptors (GABAA R) in the central nervous system establishes their central role in coordinating most aspects of neural function and development. Dysregulation of GABAergic neurotransmission manifests in a number
Autor:
Rachael K Bridgman, Rachel A Greenstein, Maxine E Wykle, Insun Chong, Harrison Friedman, Casey Hanson, Kelly Drumm, Tingting Gu, Marium Feliciano-Camacho, Juliana Broussard, Jackie Alexander, Patrick A Schneider, Joyce Stamm, Kevin M. Levine, Jennifer Bland, Zenyth A Sheppard, Marlee B Nelson, Adam S Rinaldi, John M. Braverman, Elizabeth Zavala-Arellano, Nicholas C. Spies, Kara Tsukashima, Monika C Lemke, Ellen N Niemiec, Dale L. Beach, Krystal L Holtcamp, Mitchell J McDonald, Nadia Safa, Karim A. Sharif, Martin G. Burg, Diana L. E. Johnson, Danielle R Perry, Amy S Li, Victoria R Zellmer, Jack Y. Yu, Joan Q Lawrence, Nighat P. Kokan, Raquel Montañez-Gonzalez, Kaitlin E Homa, Perouza Parsamian, Kaitlyn E Takach, Shane M. Patao, Matthew Simon, Adam C Wernette, Chun L Ng, S Mariel Ramey, Gabrielle L. Hussey, Charles R. Hauser, Karolyn Barker, Danielle M Kramer, Alexis M Ceasrine, Mariela Taboas-Arroyo, Rebekah Lee, Alexandra L Hertz, Charlotte M Brown, Gabriel Stancu, Dorianmarie Vargas-Franco, Lindsey J Suriano, Kyle L. Jung, Sami Mamari, Gary R. Skuse, Thomas J Quisenberry, Laura K. Reed, Don W. Paetkau, Victoria Chevee, Kerry Campbell, Adam Haberman, Ghazal Stity, Antoinette E. Fafara-Thompson, Breanna Haiker, Maddison F McEvilly, Isaac C Veysey-White, Robert J Allen, Susana S Apiz-Saab, Madeline M Martin, Edward Himelblau, Laura T Vives, Arielle M Vasquez, Nathan T. Mortimer, Catherine O'Keeffe, Elizabeth J Villafuerte, Shannon R. McCartha, Kirsten Bickford, Max Kollmer, Henry Z Gong, Grzegorz L. Polak, Joanna J Smith, Terrance Embry, Katelynn E Deibel, Matt Van Camp, Devon E Schultz, Sarah Wai-Chee Kong, Leah E Waldman, Suzette M. Arias-Mejias, Yakov Shevin, Richard McGuire, Danny Mammo, Sarah K Hilton, Max Mian Liu, Jaclyn D Campbell, Robert W. Fernandez, Baljit Bedi, Jordan A Black, Christopher Scheiber, Chengyu Liu, Lindsay M Prescod, Lindsay M Corbeill, Patricia N Claudio-Vazquez, Jeremy Buhler, Michael J Pavia, Holly Lyn Robbins, Luis A. Jimenez, Tanveer Sandhu, James J. Youngblom, Jordan E. Matthews, Katherine Gavinski, Rahul Nadendla, Olivia A Pahl, Hien P Nguyen, Sasha Jia, Stephanie M Grieb, Joseph E Marcus, Michael B. Schultz, Amber M. Gygi, Emily A Morlock, Karina M Gonzalez-Bonilla, Paola Villegas, Jeffrey W Wei, Christopher J. Jones, Guadalupe Quintana, Kaidi Wang, Hiu Man Vivian Tsang, Ruchik Patel, Heaven L Cerritos, Thomas C. Giarla, Gerard P. McNeil, Michael R. Rubin, Mary E Franks, Jordan R Ramirez, Maiye Her, Matt Segal, Mark Scheuerman, Emmy E. Ogawa, Darryl Lopez, Robert M. Gingras, Simon Hsu, Amy T. Hark, Zuzana Kocsisova, Dennis Revie, Christopher Bazinet, Kevin Ko, Jeremy S Davis, Deana Gabbard, Amanda Boozalis, Suchita Rastogi, Jeffery Bettincourt, Laura Schiraldi, Edward A Horansky, Amanda H Cox, Susan Parrish, Kristine Ostby, Sarah M. Jacobs, Jesse J Ensign, Kevin Kumimoto, Paul F Lee, Nicholas U. Schwartz, David D. Xiong, Susan E Herman, Allison E. McClish, Averill D Guo, Cody M Mittig, Heran Gebreyesus, Allison R Wagner, Katherine J Olson, Lucy Huo, William D. Barshop, Victoria R Sochor, Francisco J Rivera-Rosario, Samatha K Begley, James E. B. Docherty, Brandon Lee, Eric P. Spana, Abubakarr Bangura, Sarah A Einsteen, Luke Schmidt, Arianne E. Rodriguez, Samantha Parsons, Ryan Duggal, Karen Zhou, George Odisho, Tam Vuong, Erin Duso, Adam P Lousararian, Stephanie L Christ, Christopher D. Shaffer, Myrielis Rivera-Burgos, Sam Asinof, Dennis Y. Wu, Torie L Richardson, Heather L. Eisler, Allyson P Mallya, Brittney Stanton, Elizabeth J. Chen, Laurie Cannon, Briana D McRae, Peter B Lowery, Alicia R Carroll, Judith Leatherman, Guillermo Perez-Aragon, Joshua M Lorenz-Guertin, Delia Shen, Erica Enoch, Peter Wendland, Wilson Leung, Elaine R. Mardis, Adam Schefkind, Thomas Q. Xu, Wint Yan Aung, Darrin T. Schultz, Misha A Host, Hani Yosif, Ashleigh P O'Reilly, Eric Spencer, Melissa D. Patao, Jonathan M Sarezky, Matthew R Kroll, Casey L Personius, Alice Turski, Julie Beth Gillespie, S. Catherine Silver Key, Hashini Precht, Harriette Carrington, Stella Rosen, Yi Huang, Joseph Perez-Otero, Jeanette Hauke, Elizabeth A S Rettie, Petros Svoronos, Nicholaus Monsma, Kelsey F. Sugrue, Latia Britt, Tracy Wang, Patrick Gomez Menzies, Alycia Zoellner, Francesca M Gifford, Carlos F Carrion-Ortiz, Lyndsay D Kirkland, Ryan Moran, Vinayak S. Nikam, Spencer M Batten, Vanessa P Chu, Justin R. DiAngelo, Sheryl T. Smith, Ximena Velez, Tara Skorupa, Alen Ramic, Ricky Prasad, Richard Forka, Ken Saville, Ben Chlebina, Robert Franklin, Drew Miller-Foreman, Judith A Ingles, Rohit Venkat, Jennifer J Palomino, Debbie M Espada-Green, Cassie M Modahl, William A Hilton, Tracy Selfridge, Mona O Rodriguez, Samantha House, Srebrenka Robic, Sarah C. R. Elgin, Patrick Ng, Masud Karimi, Zachariah Wichman
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 7, Iss 8, Pp 2439-2460 (2017)
G3: Genes|Genomes|Genetics
G3: Genes|Genomes|Genetics
The discordance between genome size and the complexity of eukaryotes can partly be attributed to differences in repeat density. The Muller F element (∼5.2 Mb) is the smallest chromosome in Drosophila melanogaster, but it is substantially larger (>1
Autor:
Dana Molleur, Sabyasachi Das, Matthew J. Bambino, Joshua M. Lorenz-Guertin, Sammy Pardo, Tija C. Jacob, Susan T. Weintraub
Publikováno v:
The FASEB Journal. 33
Autor:
Sabyasachi Das, Joshua M. Lorenz-Guertin, Tija C. Jacob, Susan T. Weintraub, Matthew J. Bambino
Publikováno v:
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Despite 50+ years of clinical use as anxiolytics, anti-convulsants, and sedative/hypnotic agents, the mechanisms underlying benzodiazepine (BZD) tolerance are poorly understood. BZDs potentiate the actions of gamma-aminobutyric acid (GABA), the prima
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fce6d71d70f47c78339787a77d4fda10
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
GABA type A receptors (GABAARs) mediate the majority of fast inhibitory neurotransmission in the central nervous system (CNS). Most prevalent as heteropentamers composed of two α, two β, and a γ2 subunit, these ligand-gated ionotropic chloride cha