Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Joshua M. Gajsiewicz"'
Publikováno v:
Frontiers in Medicine, Vol 5 (2018)
Polyphosphate plays several roles in coagulation and inflammation, while extracellular DNA and RNA are implicated in thrombosis and as disease biomarkers. We sought to compare the procoagulant activities of polyphosphate versus DNA or RNA isolated fr
Externí odkaz:
https://doaj.org/article/e65b85dbfe4c4814aefba78907f1296e
Publikováno v:
Journal of Biological Chemistry. 292:1808-1814
The contact pathway of the plasma clotting cascade is dispensable for normal hemostasis, but contributes to thrombosis and serves as a bridge between inflammation and coagulation. This pathway is triggered upon exposure of plasma to certain anionic p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f9d9e0f467abe8a84f2585b11f0067d
https://doi.org/10.1074/jbc.m116.754325
https://doi.org/10.1074/jbc.m116.754325
Publikováno v:
Biochemistry. 54:4665-4671
The blood coagulation cascade is initiated when the cell-surface complex of factor VIIa (FVIIa, a trypsin-like serine protease) and tissue factor (TF, an integral membrane protein) proteolytically activates factor X (FX). Both FVIIa and FX bind to me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed8737b50a7b2cfda4f6ba4ff04e7bd5
https://doi.org/10.1021/acs.biochem.5b00608
https://doi.org/10.1021/acs.biochem.5b00608
Autor:
Ryan C. Bailey, Ellen M. Muehl, Zachary S. B. Wiersma, Sara M. Medfisch, James H. Morrissey, Joshua M. Gajsiewicz
Interactions of soluble proteins with the cell membrane are critical within the blood coagulation cascade. Of particular interest are the interactions of γ-carboxyglutamic acid-rich domain-containing clotting proteins with lipids. Variability among
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c855e097dbdd2fe54b43596d6cdac173
https://europepmc.org/articles/PMC5625054/
https://europepmc.org/articles/PMC5625054/
To the editor: Recent advances in understanding the contributions of the contact pathway to thrombosis, inflammation, and innate immunity[1][1] have renewed interest in identifying (patho)physiologic activators of this pathway. Candidates include col
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dc00a8dfe5526d501f8a21f0c5314f7
https://europepmc.org/articles/PMC5501151/
https://europepmc.org/articles/PMC5501151/
Autor:
James H. Morrissey, John M. Boettcher, Joshua M. Gajsiewicz, Chad M. Rienstra, Eric D. Watt, Kristin M. Nuzzio
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 9, p e0163206 (2016)
PLoS ONE, Vol 11, Iss 9, p e0163206 (2016)
In normal hemostasis, the blood clotting cascade is initiated when factor VIIa (fVIIa, other clotting factors are named similarly) binds to the integral membrane protein, human tissue factor (TF). The TF/fVIIa complex in turn activates fX and fIX, ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c53903b145e23ba56719403c10429464
https://pubmed.ncbi.nlm.nih.gov/27657719
https://pubmed.ncbi.nlm.nih.gov/27657719
Autor:
Kristin M Nuzzio, Eric D Watt, John M Boettcher, Joshua M Gajsiewicz, James H Morrissey, Chad M Rienstra
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163206 (2016)
In normal hemostasis, the blood clotting cascade is initiated when factor VIIa (fVIIa, other clotting factors are named similarly) binds to the integral membrane protein, human tissue factor (TF). The TF/fVIIa complex in turn activates fX and fIX, ev
Externí odkaz:
https://doaj.org/article/7698e29808764ebba12b298f030df4b4